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Research ArticleNeurointervention

Efficacy and Safety of Flow-Diverter Therapy for Recurrent Aneurysms after Stent-Assisted Coiling

K.Y. Park, J.Y. Yeon, B.M. Kim, P. Jeon, J.-H. Kim, C.K. Jang, D.J. Kim, J.W. Lee, Y.B. Kim, J. Chung, D.H. Song, H.G. Park and J.S. Park
American Journal of Neuroradiology March 2020, DOI: https://doi.org/10.3174/ajnr.A6476
K.Y. Park
aFrom the Department of Neurosurgery (K.Y.P., C.K.J., J.W.L., Y.B.K., J.C.), Yonsei University College of Medicine, Seoul, Republic of Korea
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J.Y. Yeon
bDepartment of Neurosurgery (J.Y.Y.), Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
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B.M. Kim
cDepartment of Radiology (B.M.K., J.-H.K., D.J.K., D.H.S., H.G.P., J.S.P.), Severance Stroke Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
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P. Jeon
dDepartment of Radiology (P.J.), Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
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J.-H. Kim
cDepartment of Radiology (B.M.K., J.-H.K., D.J.K., D.H.S., H.G.P., J.S.P.), Severance Stroke Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
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C.K. Jang
aFrom the Department of Neurosurgery (K.Y.P., C.K.J., J.W.L., Y.B.K., J.C.), Yonsei University College of Medicine, Seoul, Republic of Korea
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D.J. Kim
cDepartment of Radiology (B.M.K., J.-H.K., D.J.K., D.H.S., H.G.P., J.S.P.), Severance Stroke Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
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J.W. Lee
aFrom the Department of Neurosurgery (K.Y.P., C.K.J., J.W.L., Y.B.K., J.C.), Yonsei University College of Medicine, Seoul, Republic of Korea
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Y.B. Kim
aFrom the Department of Neurosurgery (K.Y.P., C.K.J., J.W.L., Y.B.K., J.C.), Yonsei University College of Medicine, Seoul, Republic of Korea
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J. Chung
aFrom the Department of Neurosurgery (K.Y.P., C.K.J., J.W.L., Y.B.K., J.C.), Yonsei University College of Medicine, Seoul, Republic of Korea
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D.H. Song
cDepartment of Radiology (B.M.K., J.-H.K., D.J.K., D.H.S., H.G.P., J.S.P.), Severance Stroke Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
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H.G. Park
cDepartment of Radiology (B.M.K., J.-H.K., D.J.K., D.H.S., H.G.P., J.S.P.), Severance Stroke Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
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J.S. Park
cDepartment of Radiology (B.M.K., J.-H.K., D.J.K., D.H.S., H.G.P., J.S.P.), Severance Stroke Center, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea
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    FIG 1.

    A 54-year-old man with subarachnoid hemorrhage. A, A nonenhanced CT image shows a diffuse subarachnoid hemorrhage in the basal cistern. B, A 3D volume-reconstruction image shows a fusiform aneurysm of the left distal ICA. Both the anterior choroidal (solid arrow) and posterior communicating (dashed arrow) arteries arise from the fusiform aneurysm. C, Three LVIS Blue devices are deployed in a telescopic manner from the ICA cavernous segment to the middle cerebral artery M1 segment. D, Coil embolization performed using the balloon-in-stent technique. E, Immediate postembolization shows near-complete embolization. Both the anterior choroidal (solid arrow) and posterior communicating (dashed arrow) arteries are saved. F, One-year follow-up angiogram shows a major recurrence. Note that the left anterior cerebral artery is tented due to the mass effect of the fusiform aneurysm. G, One-year follow-up angiogram after Pipeline Embolization Device implantation shows complete occlusion. H, Subtracted 3D reconstruction image shows a well-remodeled ICA with both anterior choroidal (solid arrow) and posterior communicating (dashed arrow) arteries saved.

  • FIG 2.
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    FIG 2.

    A 67-year-old woman with a partially thrombosed giant aneurysm at the anterior communicating artery. A, Angiogram immediately after LVIS Jr–assisted coiling shows complete occlusion of the aneurysm sac. B, The 14-month follow-up angiogram shows a major recurrence with occlusion of the stent. The left anterior cerebral artery A2 segment is supplied through the recurrent aneurysm sac. Note blood flow from the A1 segment through the aneurysm sac to the A2 segment. The solid arrow indicates the inflow from A1 into the aneurysm sac, and the dashed arrow indicates the outflow from the aneurysm sac to A2. C, The A2 segment is navigated through the inside of the stent using a 0.0165-inch microcatheter and a 0.014-inch microwire. Next, balloon angioplasty is performed to open the occluded stented segment of the anterior cerebral artery using a Gateway balloon (Stryker, Kalamazoo, Michigan). D, The Pipeline Flex is deployed spanning the entire stented segment. E, An angiogram immediately after PED implantation shows complete occlusion of the recurrent aneurysm. F, The 10-month follow-up angiogram shows complete occlusion of the aneurysm. MR image before PED implantation (G) and at 10-month follow-up (H) show the decreased size of the thrombosed giant aneurysm (solid arrow).

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Cite this article
K.Y. Park, J.Y. Yeon, B.M. Kim, P. Jeon, J.-H. Kim, C.K. Jang, D.J. Kim, J.W. Lee, Y.B. Kim, J. Chung, D.H. Song, H.G. Park, J.S. Park
Efficacy and Safety of Flow-Diverter Therapy for Recurrent Aneurysms after Stent-Assisted Coiling
American Journal of Neuroradiology Mar 2020, DOI: 10.3174/ajnr.A6476

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Efficacy and Safety of Flow-Diverter Therapy for Recurrent Aneurysms after Stent-Assisted Coiling
K.Y. Park, J.Y. Yeon, B.M. Kim, P. Jeon, J.-H. Kim, C.K. Jang, D.J. Kim, J.W. Lee, Y.B. Kim, J. Chung, D.H. Song, H.G. Park, J.S. Park
American Journal of Neuroradiology Mar 2020, DOI: 10.3174/ajnr.A6476
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