Involvement of the Spinal Cord in Primary Mitochondrial Disorders: A Neuroimaging Mimicker of Inflammation and Ischemia in Children

^aFrom the Division of Neuroradiology, Department of Radiology (C.A.P.F.A., S.R.T., J.S.M.S., L.C., F.G.G., A.V., G.Z.)
^bDivision of Human Genetics, Department of Pediatrics (A.G., E.M.M., M.J.F., Z.Z.-C.), Mitochondrial Medicine Frontier Program
^cDivision of Human Genetics (I. P. d.), Department of Pediatrics, Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania
^dDepartment of Neurology (G.F.)
^ePediatrics (A.G., M.J.F., Z.Z.-C.) University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania
^fCentre for Statistical Consultation (M.K.), University of Stellenbosch, South Africa
^gThe Program for the Study of Neurodevelopment in Rare Disorders (G.Z.), Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania.
^hNeuroradiology Unit (L.C.), Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, Milan, Italy

Please address correspondence to C.A.P.F. Alves, Division of Neuroradiology, Department of Radiology, Children’s Hospital of Philadelphia, Philadelphia, PA; e-mail: alvesc{at}email.chop.edu

Funding

This work was funded in part by The CHOP Mitochondrial Medicine Frontier Program and the National Institutes of Health (U24-HD093483 to M.J.F.) for the sources of research funding. The Institutional Development Fund (IDF) from the CHOP Center for Applied Genomics (CAG) supported I.P.B work.