Article Figures & Data
Figures
- FIG 1.
A 55-year-old man with a SSTR-avid mass centered in the right jugular fossa, which extends into the right middle ear cavity, measuring 3.7 × 3.6 × 3.5 cm, consistent with glomus jugulotympanicum paraganglioma. In this example, SSTR-PET/MRI findings are comparable with the extent of disease identified by contrast-enhanced MR imaging.
- FIG 2.
A 46-year-old man with a SSTR-avid homogeneously enhancing soft-tissue mass arising from the left nasal cavity, measuring 4.0 × 1.9 × 4.1 cm in anterior-posterior by transverse by craniocaudal dimensions, consistent with biopsy-proved olfactory neuroblastoma (esthesioneuroblastoma). There was no evidence of intracranial tumor extension. In this example, SSTR-PET/MRI findings are comparable with the extent of disease identified by contrast-enhanced MR imaging.
- FIG 3.
A 63-year-old woman post–right pterional craniotomy for meningioma resection with SSTR-avid recurrent meningioma arising from the right sphenoid wing and infiltrating the right orbital apex, right cavernous sinus, right sphenoid sinus, and right posterior ethmoid air cells and extending inferiorly along the right anterior temporal convexity and into the right masticator space. SSTR-positive recurrence is also noted at the right frontal craniotomy site. In this example, SSTR-PET/MRI findings were more extensive than on the basis of structural imaging because the extracranial tumor component was not identified on contrast-enhanced MR imaging.
- FIG 4.
A 31-year-old woman with a vividly enhancing submandibular mass positive for neuroendocrine markers. The patient had SSTR-avid carotid body tumors, a glomus vagale tumor, and glomus jugulare tumors bilaterally. In this example, SSTR-PET/MRI findings were more extensive than on the basis of structural imaging because the right glomus jugulare tumor was not identified on contrast-enhanced MR imaging.
- FIG 5.
A 69-year-old woman with a SSTR-avid recurrent meningioma in the right frontal parasagittal region and associated invasion of the calvaria and superior sagittal sinus. Incidentally noted is SSTR-positivity in the left temporomandibular joint with prominent articular/periarticular enhancement, suggestive of inflammatory/infectious arthritis. In this example, SSTR-PET/MRI findings are more extensive than on the basis of structural imaging because calvarial invasion was not identified by contrast-enhanced MR imaging of the brain.
- FIG 6.
A 52-year-old woman presenting with a visual field disturbance and contrast-enhanced MR imaging demonstrating a left orbital mass concerning for orbital nerve sheath meningioma versus orbital cavernous venous malformation (cavernous hemangioma). Findings of SSTR-PET were negative and represent an orbital cavernous venous malformation. The patient was subsequently referred for surgical management.
Tables
DOTATATE-PET/CT protocol parameters
Protocol PETa CTb Bed Positions Acquisition Time (Min/Bed) mA Pitch (mm/Rot) Brain 1 10 95 1.375 Fixed mA Head/neck 3 5 50–440 0.984 Auto mA Noise index 18.0 Vertex-to-thigh 7–8 5 30–440 0.984 Auto mA Noise index 28.5 Note:—Min indicates minute; Rot, rotation time.
↵a All 3D PET data were reconstructed using VUE Point FX (GE Healthcare) TOF and Sharp IR; 64Cu-DOTATATE: 256 matrix, 3 iterations, 8 subsets, “standard” z-axis filter, and a Gaussian postfilter of 7.0-mm FWHM; 68Ga DOTATATE: 192 matrix, 2 iterations, 24 subsets, standard z-axis filter, and a Gaussian postfilter of 6.4-mm FWHM.
↵b All helical CT configurations used 120 kV(peak), 3.75-mm section thickness, and a 0.8-second rotation.
