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Research ArticleHEAD AND NECK IMAGING

Comparing the Double-Echo Steady State with Water Excitation and Constructive Interference in Steady State Sequence Techniques for Identifying Extracranial Facial Nerve and Tumor Positions in Patients with Parotid Tumors

Xiaoxue Fan, Changwei Ding, Guyue Zhao and Yang Hou
American Journal of Neuroradiology August 2024, DOI: https://doi.org/10.3174/ajnr.A8309
Xiaoxue Fan
aFrom the Department of Radiology (X.F., C.D., G.Z., Y.H.), Shengjing Hospital of China Medical University, Shenyang, China
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  • ORCID record for Xiaoxue Fan
Changwei Ding
aFrom the Department of Radiology (X.F., C.D., G.Z., Y.H.), Shengjing Hospital of China Medical University, Shenyang, China
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  • ORCID record for Changwei Ding
Guyue Zhao
aFrom the Department of Radiology (X.F., C.D., G.Z., Y.H.), Shengjing Hospital of China Medical University, Shenyang, China
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Yang Hou
aFrom the Department of Radiology (X.F., C.D., G.Z., Y.H.), Shengjing Hospital of China Medical University, Shenyang, China
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  • FIG 1.
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    FIG 1.

    Standard observation slices for the image-based evaluation of the main, temporofacial, and cervicofacial trunks of the extracranial facial nerve of healthy volunteers in the oblique sagittal plane. The facial nerve shows a high signal on the DESS-WE image (A) and a low signal on the CISS image (B), with yellow arrowheads identifying the main trunk of the facial nerve, blue ones identifying the temporofacial trunk, and green ones pointing out the cervicofacial trunk.

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    FIG 2.

    Image quality assessment of parotid tumors. Representative images of the clarity of tumor lesions in DESS-WE sequence (A–C) and CISS sequence (D–F); the continuity of the facial nerve to the level of the tumor in the oblique sagittal plane (A, D); and the relative position of the facial nerve to the tumor and the diagnostic confidence of the tumor localization in the oblique sagittal (A, D), transverse (B, E), and oblique coronal planes (C, F). Yellow arrowheads identify the main trunk of the facial nerve, and red asterisks (*) denote the tumor.

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    FIG 3.

    Subjective evaluation of the quality of DESS-WE and CISS images. All subgroups, including 16 healthy volunteers (32 facial nerves) and 25 patients (30 parotid tumors), were scored on a 5-point scale for multiple parameters, with scores of ≥3 indicating satisfactory quality and scores of 1–2 indicating unsatisfactory quality.

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    Table 1:

    Parameters for DESS-WE and CISS sequences

    ParameterDESS-WECISS
    TR (ms)13.645.83
    TE (ms)4.682.57
    Section thickness0.50.5
    Field of view (mm)160 × 160160 × 160
    Matrix size320 × 320320 × 320
    Voxel size (mm)0.5 × 0.5 × 0.50.5 × 0.5 × 0.5
    Band width (Hx/pixel)315504
    Flip angle (°)2845
    Acceleration methodPAT (GRAPPA)–
    Number of acceleration factor2–
    Gradient times80 mT/m, 200 T/m/s80 mT/m, 200 T/m/s
    Number of averages11
    Fat suppressionWater excitation–
    Number of sections160160
    Acquisition time7 minutes, 39 seconds10 minutes, 18 seconds
    • Note:—GRAPPA indicates generalized autocalibrating partially parallel acquisitions; PAT, parallel acquisition technique.

    • View popup
    Table 2:

    SNR and CNR of DESS-WE and CISS

    ParticipantsDESS-WE Mean ± SD (Range)CISS Mean ± SD (Range)P
    SNR
    Healthy volunteers17.14 ± 3.19 (9.42–21.99)49.81 ± 11.27 (29.65–73.27)<.001
    Patients17.13 ± 5.00 (8.27–26.34)46.85 ± 14.11 (30.26–102.45)<.001
    Overall17.14 ± 4.13 (8.27–26.34)48.38 ± 12.70 (29.65–102.45)<.001
    CNR
    Healthy volunteers7.07 ± 2.39 (2.88–11.73)54.10 ± 17.07 (25.18–91.20)<.001
    Patients7.26 ± 3.65 (1.49–14.83)50.45 ± 13.39 (29.39–80.24)<.001
    Overall7.21 ± 2.94 (1.49–14.83)52.33 ± 15.38 (24.18–91.20)<.001
    • View popup
    Table 3:

    Intra- and interrater agreements for the image quality of DESS-WE and CISS

    ParticipantsSegmentationDESS-WECISS
    Interrater κ (95% CI)Healthy volunteersFacial nerve trunk visibility0.724 (0.477–0.971)0.796 (0.660–0.994)
    Temporofacial trunk visibility0.753 (0.533–0.972)0.816 (0.644–0.988)
    Cervicofacial trunk visibility0.738 (0.522–0.954)0.809 (0.635–0.983)
    Intrarater κ (95% CI)Healthy volunteersFacial nerve trunk visibility0.740 (0.503–0.977)0.783 (0.580–0.995)
    Temporofacial trunk visibility0.759 (0.553–0.966)0.805 (0.623–0.986)
    Cervicofacial trunk visibility0.728 (0.487–0.968)0.755 (0.557–0.952)
    Interrater κ (95% CI)PatientsClarity of tumor margin0.841 (0.692–0.989)0.797 (0.625–0.968)
    Continuity0.810 (0.646–0.974)0.774 (0.551–0.997)
    Spatial relationship0.793 (0.624–0.963)0.784 (0.575–0.993)
    Diagnostic confidence0.784 (0.638–0.931)0.780 (0.566–0.994)
    Intrarater κ (95% CI)PatientsClarity of tumor margin0.817 (0.651–0.982)0.763 (0.584–0.943)
    Continuity0.794 (0.604–0.982)0.757 (0.568–0.946)
    Spatial relationship0.854 (0.726–0.983)0.779 (0.563–0.996)
    Diagnostic confidence0.870 (0.750–0.989)0.786 (0.584–0.989)
    • Note:—Continuity indicates continuity of the facial nerve trunk from the foramen to the level of the parotid tumor; spatial relationship, the relative position of the facial nerve in relation to the tumor.

    • View popup
    Table 4:

    Visibility of the DESS-WE and CISS images for the localization of parotid tumors (n = 30)

    Imaging FindingsSurgical FindingsDiagnostic Performance
    Deep Lobe +Deep Lobe −AUC (95% CI)AccuracySensitivitySpecificity
    DESS-WE
     Deep lobe +430.942 (0.792–0.994)90%100%88.5%
     Deep lobe −023
    CISS
     Deep lobe +410.981 (0.850–1.000)96.7%100%96.2%
     Deep lobe −025
    P0.1489
    • Note:—AUC indicates area under the curve.

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Xiaoxue Fan, Changwei Ding, Guyue Zhao, Yang Hou
Comparing the Double-Echo Steady State with Water Excitation and Constructive Interference in Steady State Sequence Techniques for Identifying Extracranial Facial Nerve and Tumor Positions in Patients with Parotid Tumors
American Journal of Neuroradiology Aug 2024, DOI: 10.3174/ajnr.A8309

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Comparing the Double-Echo Steady State with Water Excitation and Constructive Interference in Steady State Sequence Techniques for Identifying Extracranial Facial Nerve and Tumor Positions in Patients with Parotid Tumors
Xiaoxue Fan, Changwei Ding, Guyue Zhao, Yang Hou
American Journal of Neuroradiology Aug 2024, DOI: 10.3174/ajnr.A8309
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