- Skull Base CSF Leaks: Potential Underlying Pathophysiology and Evaluation of Brain MR Imaging Findings Associated with Spontaneous Intracranial Hypotension
The purpose of this study was to use a validated brain MRI scoring system (Bern score) to evaluate patients with confirmed skull base CSF leaks for findings associated with SIH. The authors found that patients with skull base CSF leaks did not have brain MRI findings that are associated with SIH and likely have distinct pathophysiology from spinal CSF leaks.
- Risk of Hemorrhagic Transformation after Mechanical Thrombectomy without versus with IV Thrombolysis for Acute Ischemic Stroke: A Systematic Review and Meta-analysis of Randomized Clinical Trials
This systematic review and meta-analysis evaluated the risk of intracerebral hemorrhage, and its subtypes associated with mechanical thrombectomy with or without IV thrombolysis for the treatment of acute ischemic stroke due to large-vessel occlusion. The analysis showed that the overall risk of symptomatic intracerebral hemorrhage was comparable between mechanical thrombectomy with IV thrombolysis and mechanical thrombectomy alone.
- An Optimized CT Protocol for Detecting Suspected Cauda Equina Syndrome: A Comparative Analysis with MRI
This study prospectively evaluated the diagnostic accuracy of an optimized CT lumbar spine protocol as a potential alternative to MRI in assessing suspected neural compression. CT accurately identified all cases requiring urgent decompression. CT had 97% sensitivity, specificity, and positive and negative predictive values in detecting disc pathology in patients presenting with symptoms suggestive of acute neural compression compared with MRI.