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Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

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MY CONTENT

  • Adult Brain
    Open Access
    Dynamic Contrast-Enhanced MR Imaging of Nonenhancing T2 High-Signal-Intensity Lesions in Baseline and Posttreatment Glioblastoma: Temporal Change and Prognostic Value
    I. Hwang, S.H. Choi, C.-K. Park, T.M. Kim, S.-H. Park, J.K. Won, I.H. Kim, S.-T. Lee, R.-E. Yoo, K.M. Kang, T.J. Yun, J.-H. Kim and C.-H. Sohn
    American Journal of Neuroradiology January 2020, 41 (1) 49-56; DOI: https://doi.org/10.3174/ajnr.A6323
  • EDITOR'S CHOICESpine
    You have access
    Number Needed to Treat with Vertebral Augmentation to Save a Life
    J.A. Hirsch, R.V. Chandra, N.S. Carter, D. Beall, M. Frohbergh and K. Ong
    American Journal of Neuroradiology January 2020, 41 (1) 178-182; DOI: https://doi.org/10.3174/ajnr.A6367

    The purpose of this study was to calculate the number needed to treat to save 1 life at 1 year and up to 5 years after vertebral augmentation. A 10-year sample of the 100% US Medicare data base was used to identify patients with vertebral compression fractures treated with nonsurgical management, balloon kyphoplasty, and vertebroplasty. The number needed to treat was calculated between augmentation and nonsurgical management groups from years 1–5 following a vertebral compression fracture diagnosis, using survival probabilities for each management approach. The adjusted number needed to treat to save 1 life for nonsurgical management versus kyphoplasty ranged from 14.8 at year 1 to 11.9 at year 5. The adjusted number needed to treat for nonsurgical management versus vertebroplasty ranged from 22.8 at year 1 to 23.8 at year 5. The authors conclude that the NNT analysis of more than 2 million patients with VCF reveals that only 15 patients need to be treated to save 1 life at 1 year. This has an obvious clinically significant impact and given that all augmentation clinical trials are underpowered to detect a mortality benefit, this large dataset analysis reveals that vertebral augmentation provides a significant mortality benefit over nonsurgical management with a low NNT.

  • Adult Brain
    You have access
    High-Resolution MRI for Evaluation of Ventriculostomy Tubes: Assessment of Positioning and Proximal Patency
    A.M. Blitz, P.P. Huynh, L.W Bonham, S.K. Gujar, D.E. Sorte, A. Moghekar, M.G. Luciano and D. Rigamonti
    American Journal of Neuroradiology January 2020, 41 (1) 57-63; DOI: https://doi.org/10.3174/ajnr.A6320
  • Spine
    You have access
    Simple Fluoroscopy-Guided Transforaminal Lumbar Puncture: Safety and Effectiveness of a Coaxial Curved-Needle Technique in Patients with Spinal Muscular Atrophy and Complex Spines
    J.P. Jacobson, B.C. Cristiano and D.R. Hoss
    American Journal of Neuroradiology January 2020, 41 (1) 183-188; DOI: https://doi.org/10.3174/ajnr.A6351
  • EDITOR'S CHOICEAdult Brain
    You have access
    Prediction of Hemorrhage after Successful Recanalization in Patients with Acute Ischemic Stroke: Improved Risk Stratification Using Dual-Energy CT Parenchymal Iodine Concentration Ratio Relative to the Superior Sagittal Sinus
    D. Byrne, J.P. Walsh, H. Schmiedeskamp, F. Settecase, M.K.S. Heran, B. Niu, A.K. Salmeen, B. Rohr, T.S. Field, N. Murray and A. Rohr
    American Journal of Neuroradiology January 2020, 41 (1) 64-70; DOI: https://doi.org/10.3174/ajnr.A6345

    The authors evaluated whether, in acute ischemic stroke, iodine concentration within contrast-stained parenchyma compared with an internal reference in the superior sagittal sinus on dual-energy CT could predict subsequent intracerebral hemorrhage in 71 patients. Forty-three of 71 patients had parenchymal hyperdensity on initial dual-energy CT. The median relative iodine concentration compared with the superior sagittal sinus was significantly higher in those with subsequent intracerebral hemorrhage (137.9% versus 109.2%). They conclude that in dual-energy CT performed within 1 hour following thrombectomy that the relative iodine concentration within contrast-stained brain parenchyma compared with that in the superior sagittal sinus was a more reliable predictor of ICH compared with the absolute maximum iodine concentration.

  • Adult Brain
    You have access
    Diffusion Properties of Normal-Appearing White Matter Microstructure and Severity of Motor Impairment in Acute Ischemic Stroke
    C. Ingo, C. Lin, J. Higgins, Y.A. Arevalo and S. Prabhakaran
    American Journal of Neuroradiology January 2020, 41 (1) 71-78; DOI: https://doi.org/10.3174/ajnr.A6357
  • Adult Brain
    Open Access
    Structural and Volumetric Brain MRI Findings in Mild Traumatic Brain Injury
    J.B. Patel, S.H. Wilson, T.R. Oakes, P. Santhanam and L.K. Weaver
    American Journal of Neuroradiology January 2020, 41 (1) 92-99; DOI: https://doi.org/10.3174/ajnr.A6346
  • Adult Brain
    You have access
    Microstructural Integrity of Salvaged Penumbra after Mechanical Thrombectomy
    M.T. Berndt, C. Maegerlein, T. Boeckh-Behrens, S. Wunderlich, C. Zimmer, S. Wirth, F.G. Mück, S. Mönch, B. Friedrich and J. Kaesmacher
    American Journal of Neuroradiology January 2020, 41 (1) 79-85; DOI: https://doi.org/10.3174/ajnr.A6364
  • FELLOWS' JOURNAL CLUBAdult Brain
    Open Access
    Vessel Wall Thickening and Enhancement in High-Resolution Intracranial Vessel Wall Imaging: A Predictor of Future Ischemic Events in Moyamoya Disease
    A. Kathuveetil, P.N. Sylaja, S. Senthilvelan, K. Chandrasekharan, M. Banerjee and B. Jayanand Sudhir
    American Journal of Neuroradiology January 2020, 41 (1) 100-105; DOI: https://doi.org/10.3174/ajnr.A6360

    Twenty-nine patients with Moyamoya disease were enrolled in this study. The median age at symptom onset was 12 years. A total of 166 steno-occlusive lesions were detected by high-resolution intracranial vessel wall imaging. Eleven lesions with concentric wall thickening (6.6%) were noted in 9 patients. Ten concentric contrast-enhancing lesions were observed in 8 patients, of which 4 lesions in 3 patients showed grade II enhancement. The presence of contrast enhancement and wall thickening showed a statistically significant association with ischemic events within 3 months before and after the vessel wall imaging. The presence of wall thickening and enhancement may predict future ischemic events in patients with MMD.

  • Adult Brain
    You have access
    Usefulness of Contrast-Enhanced 3D-FLAIR MR Imaging for Differentiating Rathke Cleft Cyst from Cystic Craniopharyngioma
    M. Azuma, Z.A. Khant, M. Kitajima, H. Uetani, T. Watanabe, K. Yokogami, H. Takeshima and T. Hirai
    American Journal of Neuroradiology January 2020, 41 (1) 106-110; DOI: https://doi.org/10.3174/ajnr.A6359

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