- The Choroid Plexus as an Alternative Locus for the Identification of the Arterial Input Function for Calculating Cerebral Perfusion Metrics Using MRI
MR imaging-based cerebral perfusion metrics can be obtained by tracing a contrast bolus through the brain microvasculature. The authors compared the calculated resting relative perfusion metrics obtained from the choroid plexus (CP) with those obtained from the middle cerebral artery (MCA) in healthy participants and patients with glioma. The findings of this study suggest that an arterial input function chosen from within the CP is comparable with one chosen from the MCA and may be an alternative, particularly when there is no suitable MCA location to interrogate.
- CTA and CTP for Detecting Distal Medium Vessel Occlusions: A Systematic Review and Meta-analysis
This systematic review and meta-analysis aimed to compare the diagnostic test accuracy for CTA and CTP in the detection of distal medium vessel occlusion. The study found consistent evidence for a higher sensitivity in detecting distal medium vessel occlusion, particularly in arteries beyond the M2 segment of MCA, with multiphase CTA or CTP compared with single-phase CTA.
- Prevalence and Characteristics of Intracranial Aneurysms in Hereditary Hemorrhagic Telangiectasia
In this retrospective study, the authors evaluated the prevalence and characteristics of intracranial aneurysms in patients with hereditary hemorrhagic telangiectasia with brain vascular malformations. In their study cohort of 180 patients with HHT and brain vascular malformations, the authors demonstrated that the prevalence of intracranial aneurysm in hereditary hemorrhagic telangiectasia is comparable with that in the general population without clear association with shunting brain vascular malformations.
- DWI-Detected Ischemic Lesions after Endovascular Treatment for Cerebral Aneurysms: An Updated Systematic Review and Meta-analysis
This systematic review and meta-analysis found the incidence of new postprocedural DWI-detected ischemic lesions after endovascular treatment for intracranial aneurysms to be 47.0% (95% CI, 39.6%–55.8%), regardless of the endovascular procedure used. Studies have shown that almost half of these lesions are asymptomatic, and if small (<5 mm), these lesions have been shown to regress without negative effect on clinical outcome.
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