- Hemodynamic Analysis of Postoperative Rupture of Unruptured Intracranial Aneurysms after Placement of Flow-Diverting Stents: A Matched Case-Control Study
The authors enrolled 10 patients with intracranial aneurysms, treated with flow diverters between September 2014 and December 2018, who experienced postoperative aneurysm rupture. They matched these subjects 1:2 with 20 with postoperative unruptured intracranial aneurysms based on clinical and morphologic factors. Using computational fluid dynamics, they assessed hemodynamic changes pre- and posttreatment between the 2 groups on a number of qualitative and quantitative parameters. Compared with pretreatment, unstable flow pattern and higher energy loss after Pipeline Embolization Device placement for intracranial aneurysm may be the important hemodynamic risk factors related to delayed aneurysm rupture.
- Incidental Brain MRI Findings in Children: A Systematic Review and Meta-Analysis
Seven studies were included, reporting 5938 children (mean age, 11.3 ± 2.8 years). Incidental findings were present in 16.4% of healthy children, intracranial cysts being the most frequent (10.2%). Nonspecific white matter hyperintensities were reported in 1.9%, Chiari I malformation was found in 0.8%, and intracranial neoplasms were reported in 0.2%. In total, the prevalence of incidental findings needing follow-up was 2.6%. The prevalence of incidental findings is much more frequent in children than previously reported in adults, but clinically significant incidental findings were present in <1 in 38 children.
- Cerebral Venous Thrombosis: MR Black-Blood Thrombus Imaging with Enhanced Blood Signal Suppression
Twenty-six participants underwent conventional imaging methods followed by 2 randomized black-blood thrombus imaging scans, with a preoptimized DANTE preparation switched on and off, respectively. The signal intensity of residual blood, thrombus, brain parenchyma, normal lumen, and noise on black-blood thrombus images were measured. The thrombus volume, SNR of residual blood, and contrast-to-noise ratio for residual blood versus normal lumen, thrombus versus residual blood, and brain parenchyma versus normal lumen were compared between the 2 black-blood thrombus imaging techniques. The new black-blood thrombus imaging technique provided higher thrombus-to-residual blood contrast-to-noise ratio, significantly lower thrombus volume, and substantially improved diagnostic specificity and agreement with conventional imaging methods.