Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticleBRAIN

Proton MR Spectroscopic Evaluation of Suspicious Brain Lesions After Stereotactic Radiotherapy

Heinz–Peter Schlemmer, Peter Bachert, Klaus K. Herfarth, Ivan Zuna, Jürgen Debus and Gerhard van Kaick
American Journal of Neuroradiology August 2001, 22 (7) 1316-1324;
Heinz–Peter Schlemmer
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peter Bachert
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Klaus K. Herfarth
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ivan Zuna
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jürgen Debus
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Gerhard van Kaick
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    van Kampen M, Engenhart-Cabillic R, Debus J, Hess T, Schad LR, Wannenmacher MF. Low-grade astrocytoma: treatment with conventionally fractionated stereotactic radiation therapy. Radiology 1996;201:275-278
    PubMed
  2. ↵
    Schultheiss TE, Kun LE, Ang KK, Stephens LC. Radiation response of the central nervous system. Int J Radiat Oncol Biol Phys 1995;31:1093-1112
    CrossRefPubMedWeb of Science
  3. ↵
    Sheline GE, Wara WM, Smith V. Therapeutic irradiation and brain injury. Int J Radiat Oncol Biol Phys 1980;6:1215-1228
    CrossRefPubMedWeb of Science
  4. ↵
    Frahm J, Bruhn H, Gyngell ML, Merboldt KD, Hänicke W, Sauter R. Localized high–resolution proton NMR spectroscopy using stimulated echoes: initial applications to human brain in vivo. Magn Reson Med 1989;9:79-93
    CrossRefPubMedWeb of Science
  5. Ross B, Michaelis T. Clinical applications of magnetic resonance spectroscopy. Magn Reson Q 1994;10:191-247
    PubMedWeb of Science
  6. ↵
    Alger JR, Frank JA, Bizzi A, Fuhlham MJ, et al. Metabolism of human gliomas: Assessment with H–1 MR spectroscopy and F–18 fluorodeoxyglucose PET. Radiology 1990;177:633-641
    PubMedWeb of Science
  7. Ott D, Hennig J, Ernst T. Human brain tumors: assessment with in vivo proton MR spectroscopy. Radiology 1993;186:745-752
    PubMedWeb of Science
  8. Tien RD, Lai PH, Smith JS, Lazeyras F. Single-voxel proton brain spectroscopy exam (PROBE/SV) in patients with primary brain tumors. AJR Am J Roentgenol 1996;167:201-219
    PubMedWeb of Science
  9. ↵
    Preul MC, Caramanos Z, Leblanc R, Villemure JG, Arnold DL. Using pattern analysis of in vivo proton MRSI data to improve the diagnosis and surgical management of patients with brain tumors. NMR Biomed 1998;11:192-200
    CrossRefPubMedWeb of Science
  10. ↵
    Adamson AJ, Rand SD, Prost RW, Kim TA, Schultz C, Haughton VM. Focal brain lesions: effect of single-voxel proton MR spectroscopic findings on treatment decisions. Radiology 1998;209:73-78
    PubMed
  11. ↵
    Fulham MJ, Bizzi A, Dietz MJ, et al. Mapping of brain tumor metabolites with proton MR spectroscopic imaging: clinical relevance. Radiology 1992;185:675-686
    PubMed
  12. Lin A, Bluml S, Mamelak N. Efficacy of proton magnetic resonance spectroscopy in clinical decision making for patients with suspicious malignant brain tumors. J Neurooncol 1999;45:69-81
    CrossRefPubMed
  13. Rand SD, Prost R, Haughton V, et al. Accuracy of single-voxel proton MR spectroscopy in distinguishing neoplastic from non-neoplastic brain lesions. AJNR Am J Neuroradiol 1997;18:1695-1704
    Abstract
  14. ↵
    Debus J, Engenhart-Cabillic R, Knopp MV, Schad LR, Schlegel W, Wannenmacher M. Image-oriented planning of minimally invasive conformal irradiation of the head-neck area. Radiologie 1996;36:732-736
  15. ↵
    Pirzkall A, Debus J, Lohr F, et al. Radiosurgery alone or in combination with whole-brain radiotherapy for brain metastases. J Clin Oncol 1998;16:3563-3569
    Abstract
  16. ↵
    Duda RO, Hart PE. Pattern Classification and Scene Analysis. John Wiley & Sons, Inc.;1973:130–159
  17. ↵
    Di Chiro G, Oldfield E, Wright DC, et al. Cerebral necrosis after irradiation and/or intraarterial chemotherapy for brain tumors: PET and neuropathologic studies. AJR Am J Roentgenol 1988;150:189-197
    PubMedWeb of Science
  18. Patronas NJ, Di Chiro G, Brooks RA, et al. Work in progress: [18F] fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain. Radiology 1982;144:885-889
    PubMedWeb of Science
  19. ↵
    Heesters MA, Kamman RL, Mooyaart EL, Go KG. Localized proton spectroscopy of inoperable brain gliomas. Response to radiation therapy. J Neurooncol 1993;17:27-35
    CrossRefPubMed
  20. ↵
    Wald LL, Nelson SJ, Day MR, et al. Serial proton magnetic resonance spectroscopy imaging of glioblastoma multiforme after brachytherapy. J Neurosurg 1997;87:525-534
    PubMedWeb of Science
  21. Kamada K, Houkin K, Abe H, Sawamura Y, Kashiwaba T. Differentiation of cerebral radiation necrosis from tumor recurrence by proton magnetic resonance spectroscopy. Neurol Med Chir (Tokyo) 1997;37:250-256
    CrossRefPubMed
  22. ↵
    Kizu O, Naruse S, Furuya S, et al. Application of proton chemical shift imaging in monitoring of gamma knife radiosurgery on brain tumors. Magn Reson Imaging 1998;16:197-204
    CrossRefPubMed
  23. ↵
    Lee PL, Rabinov J, Cheng LL, Henson JW, Louis DN, Gonzalez RG. Differentiation between brain tumor recurrence and radiation effects: correlation of in vivo MRS at 3T and ex vivo high-resolution magic-angle spinning MRS and histopathology. Proc Intl Soc Magn Reson Med 1999;7:432
  24. Nelson SJ, Huhn S, Vigneron DB, et al. Volume MRI and MRSI techniques for the quantification of treatment response in brain tumors: presentation of a detailed case study. J Magn Reson Imaging 1997;7:1146-1152
    PubMed
  25. Preul MC, Leblanc R, Caramanos Z, Kasrai R, Narayanan S, Arnold DL. Magnetic resonance spectroscopy guided brain tumor resection: differentiation between recurrent glioma and radiation change in two diagnostically difficult cases. Can J Neurol Sci 1998;25:13-22
    PubMed
  26. Taylor JS, Langston JW, Reddick WE, et al. Clinical value of proton magnetic resonance spectroscopy for differentiating recurrent or residual brain tumor from delayed cerebral necrosis. Int J Radiat Oncol Biol Phys 1996;36:1251-1261
    CrossRefPubMed
  27. ↵
    Krouwer HG, Kim TA, Rand SD, et al. Single-voxel proton MR spectroscopy of non-neoplastic brain lesions suggestive of a neoplasm. AJNR Am J Neuroradiol 1998;19:1695-1703
    Abstract
  28. ↵
    Chan YL, Yeung D, Leung SF, Cao G. Proton magnetic resonance spectroscopy of late delayed radiation-induced injury of the brain. J Magn Reson Imaging 1999;10:130-137
    CrossRefPubMedWeb of Science
  29. ↵
    Estève F, Rubin C, Grand S, Kolodié H, Le Bas JF. Transient metabolic changes observed with proton MR spectroscopy in normal human brain after radiation therapy. Int J Radiat Oncol Biol Phys 1998;40:279-286
    CrossRefPubMedWeb of Science
  30. ↵
    Szigety SK, Allen PS, Huyser-Wierenga D, Urtasun RC. The effect of radiation on normal human CNS as detected by NMR spectroscopy. Int J Radiat Oncol Biol Phys 1993;25:695-701
    PubMedWeb of Science
  31. Bruhn H, Frahm J, Gyngell ML, et al. Noninvasive differentiation of tumors using localized H–1 spectroscopy in vivo: initial experience in patients with cerebral tumors. Radiology 1989;172:541-548
    PubMedWeb of Science
  32. ↵
    Yousem DM, Lenkinski RE, Evans S, et al. Proton MR spectroscopy of experimental radiation-induced white matter injury. J Comput Assist Tomogr 1992;16:543-548
    PubMed
  33. ↵
    Saunders DE, Howe FA, van den Boogaart A, Griffiths JR, Brown MM. Aging of the adult human brain: in vivo quantitation of metabolite content with proton magnetic resonance spectroscopy. J Magn Reson Imaging 1999;9:711-716
    CrossRefPubMedWeb of Science
  34. ↵
    Sijens PE, van den Bent MJ, Nowak PJ, van Dijk P, Oudkerk M. 1H chemical shift imaging reveals loss of brain tumor choline signal after administration of Gd-contrast. Magn Reson Med 1997;37:222-225
    PubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 22 (7)
American Journal of Neuroradiology
Vol. 22, Issue 7
1 Aug 2001
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Proton MR Spectroscopic Evaluation of Suspicious Brain Lesions After Stereotactic Radiotherapy
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Heinz–Peter Schlemmer, Peter Bachert, Klaus K. Herfarth, Ivan Zuna, Jürgen Debus, Gerhard van Kaick
Proton MR Spectroscopic Evaluation of Suspicious Brain Lesions After Stereotactic Radiotherapy
American Journal of Neuroradiology Aug 2001, 22 (7) 1316-1324;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Proton MR Spectroscopic Evaluation of Suspicious Brain Lesions After Stereotactic Radiotherapy
Heinz–Peter Schlemmer, Peter Bachert, Klaus K. Herfarth, Ivan Zuna, Jürgen Debus, Gerhard van Kaick
American Journal of Neuroradiology Aug 2001, 22 (7) 1316-1324;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusion
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • MR Spectroscopy in Radiation Injury
  • Distinguishing Recurrent Intra-Axial Metastatic Tumor from Radiation Necrosis Following Gamma Knife Radiosurgery Using Dynamic Susceptibility-Weighted Contrast-Enhanced Perfusion MR Imaging
  • MGMT Promoter Methylation Status Can Predict the Incidence and Outcome of Pseudoprogression After Concomitant Radiochemotherapy in Newly Diagnosed Glioblastoma Patients
  • Diagnostic performance of spectroscopic and perfusion MRI for distinction of brain tumors
  • Physiologic and Metabolic Magnetic Resonance Imaging in Gliomas
  • PET and SPECT for Detection of Tumor Progression in Irradiated Low-Grade Astrocytoma: A Receiver-Operating-Characteristic Analysis
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Statin Therapy Does Not Affect the Radiographic and Clinical Profile of Patients with TIA and Minor Stroke
  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
  • SWI or T2*: Which MRI Sequence to Use in the Detection of Cerebral Microbleeds? The Karolinska Imaging Dementia Study
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire