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Research ArticleBrain

Hemodynamic Modifications in Patients with Symptomatic Unilateral Stenosis of the Internal Carotid Artery: Evaluation with MR Imaging Perfusion Sequences

Alessandro Bozzao, Roberto Floris, Fabrizio Gaudiello, Vanina Finocchi, Luigi Maria Fantozzi and Giovanni Simonetti
American Journal of Neuroradiology September 2002, 23 (8) 1342-1345;
Alessandro Bozzao
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Roberto Floris
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Fabrizio Gaudiello
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Vanina Finocchi
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Luigi Maria Fantozzi
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Giovanni Simonetti
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    Fig 1.

    A–D, Left, Schematic representations of the MCA (blue in A) and border zone (red in B–D) territories. A–D, Right, Perfusion maps of rCBV show the ROIs (black outlines) positioned in MCA (A) and border zone (B–D) territories.

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    Fig 2.

    Comparison of perfusion data in the MCA (symbols 1–4) and border zone (symbols 5–8) territories between the control group (3, 4, 7, 8) and patients with ICA stenosis (1, 2, 5, 6).

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    TABLE 1:

    rCBV and MTT Values, Normalized to Cerebellum, in the Hemispheres Supplied by Normal and Stenotic ICAs in the MCA and Border Zone Territories

    Degree of Stenosis by NASCET (%)Age (y)/SexrCBV MCArCBV Border ZoneMTT MCAMTT Border Zone
    Normal SideStenotic SideNormal SideStenotic SideNormal SideStenotic SideNormal SideStenotic Side
    7062/M0,770,810,710,681,291,281,261,28
    7578/M1,051,110,780,741,291,361,341,35
    8056/F0,870,750,920,920,720,680,970,89
    8062/F0,660,760,750,750,930,911,451,41
    8079/F1,151,170,680,721,121,171,191,17
    7074/M0,960,910,60,770,720,680,760,76
    7571/F1,151,170,961,021,221,121,351,43
    7559/F0,770,820,560,691,161,11,121,26
    8565/M1,130,970,880,870,720,60,710,66
    9067/M0,921,010,740,741,041,471,040,96
    8073/M0,790,820,790,730,80,790,820,69
    9064/M0,860,980,650,771,281,31,131,31
    7058/F1,151,081,010,891,51,261,51,53
    8066/M1,121,020,970,881,31,211,121,05
    8573/M0,980,940,840,780,911,0210,97
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    TABLE 2:

    Mean rCBV and MTT Values, Normalized to Cerebellum, of Both Hemispheres in MCA and Border Zone Territories in Control Subjects and Patients

    SubjectsMCABorder Zone
    rCBVMTTCBVMTT
    Controls1,020,960,850,95*
    Patients
     Normal side0,941,060,771,12*
     Stenotic side0,951,050,791,13*
    • * A statistically significant difference was found between MTT in the border zone of patients and control subjects (P = .05).

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American Journal of Neuroradiology: 23 (8)
American Journal of Neuroradiology
Vol. 23, Issue 8
1 Sep 2002
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Alessandro Bozzao, Roberto Floris, Fabrizio Gaudiello, Vanina Finocchi, Luigi Maria Fantozzi, Giovanni Simonetti
Hemodynamic Modifications in Patients with Symptomatic Unilateral Stenosis of the Internal Carotid Artery: Evaluation with MR Imaging Perfusion Sequences
American Journal of Neuroradiology Sep 2002, 23 (8) 1342-1345;

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Hemodynamic Modifications in Patients with Symptomatic Unilateral Stenosis of the Internal Carotid Artery: Evaluation with MR Imaging Perfusion Sequences
Alessandro Bozzao, Roberto Floris, Fabrizio Gaudiello, Vanina Finocchi, Luigi Maria Fantozzi, Giovanni Simonetti
American Journal of Neuroradiology Sep 2002, 23 (8) 1342-1345;
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