Research ArticleBRAIN
Standardized, Reproducible, High Resolution Global Measurements of T1 Relaxation Metrics in Cases of Multiple Sclerosis
Radhika Srinivasan, Roland Henry, Daniel Pelletier and Sarah Nelson
American Journal of Neuroradiology January 2003, 24 (1) 58-67;
Radhika Srinivasan
Roland Henry
Daniel Pelletier

References
- ↵Filippi M, Horsfield MA, Tofts PS, Barkhof F, Thompson AJ, Miller DH. Quantitative assessment of MRI lesion load in monitoring the evolution of multiple sclerosis. Brain 1995;118:1601–1612
- ↵van Walderween MA, Barkhof F, Hommes OR, et al. Correlating MRI and clinical disease activity in multiple sclerosis: relevance of hypointense lesions on short-TR/short-TE (T1-weighted) spin-echo images. Neurology 1995;45:1684–1690
- ↵Fu L, Matthews PM, De Stefano N, et al. Imaging axonal damage of normal-appearing white matter in multiple sclerosis. Brain 1998;121:103–113
- Tortorella C, Viti B, Bozzali M, et al. A magnetization transfer histogram study of normal-appearing brain tissue in MS. Neurology 2000;54:186–193
- ↵Sharma R, Narayana PA, Wolinsky JS. Grey matter abnormalities in multiple sclerosis: proton magnetic resonance imaging. Mult Scler 2001;7:221–226
- ↵Alfano B, Brunetti A, Covelli EM. Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric MR approach. Magn Reson Med 1997;37:84–93
- ↵Alfano B, Brunetti A, Larobina M, et al. Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis. J Magn Reson Imaging 2000;12:799–807
- ↵Vinitski S, Gonzalez C, Mohamed F. Improved intracranial lesion characterization by tissue segmentation based on a 3D feature map. Magn Reson Med 1997;37:457–469
- ↵Hanicke W, Merboldt K-D, Frahm J. Slice selection and T1 contrast in FLASH NMR imaging. J Magn Reson 1988;77:64–74
- ↵Parker GJ, Barker GJ, Tofts PS. Accurate multislice gradient echo T1 measurement in the presence of non-ideal RF pulse shape and RF field homogeneity. Magn Reson Med 2001;45:838–845
- ↵
- ↵Brookes JA, Redpath TW, Gilbert FJ, Needham G, Murray AD. Measurement of spin-lattice relaxation times with FLASH for dynamic MRI of the breast. Br J Radiol 1996;69:206–214
- ↵Poser CM, Paty DW, Scheinberg L, McDonald WI, Davis FA, Ebers GC. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann Neurol 1983;13:227–231
- ↵Filippi M, Rocca MA, Horsfield MA, et al. Increased spatial resolution using a three-dimensional T1-weighted gradient-echo MR sequence results in greater hypointense lesion volumes in multiple sclerosis. AJNR Am J Neuroradiol 1998;19:235–238
- ↵
- ↵Fram EV, Herfkens RJ, Johnson, GA, et al. Rapid calculation of T1 using variable flip angle gradient refocused imaging. Magn Reson Imaging 1987;5:201–208
- ↵Rovaris M, Inglese M, Schijndel RA, et al. Sensitivity and reproducibility of volume change measurements of different brain portions on magnetic resonance imaging in patients with multiple sclerosis. J Neurol 2000;247:960–965
- ↵Jackson EF, Narayana PA, Falconer JC. Reproducibility of non-parametric feature map segmentation for determination of normal human intra-cranial volumes using MR imaging data. J Magn Reson Imaging 1994;4:692–700
- ↵Harris GJ, Barta PE, Peng LW. MR volume segmentation of gray matter and white matter using manual thresholding: dependence on image brightness. AJNR Am J Neuroradiol 1994;15:225–230
- ↵Narayana PA, Borthakur A. Effect of radio frequency inhomogeneity correction on the reproducibility of intra-cranial volumes using MR image data. Magn Reson Med 1995;33:396–400
- ↵Chard DT, Parker GJ, Griffin CM, Thompson AJ, Miller DH. The reproducibility and sensitivity of brain tissue volume measurements derived from an SPM-based segmentation methodology. J Magn Reson Imaging 2002;15:259–267
- ↵Ashburner J, Friston KJ. Voxel-based morphometry: the methods. Neuroimage 2000;11:805–821
In this issue
Advertisement
Radhika Srinivasan, Roland Henry, Daniel Pelletier, Sarah Nelson
Standardized, Reproducible, High Resolution Global Measurements of T1 Relaxation Metrics in Cases of Multiple Sclerosis
American Journal of Neuroradiology Jan 2003, 24 (1) 58-67;
0 Responses
Jump to section
Related Articles
- No related articles found.
Cited By...
This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.
More in this TOC Section
Similar Articles
Advertisement