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Research ArticleBRAIN

Cavernous Carotid Artery Calcification and White Matter Ischemia

Lukasz S. Babiarz, David M. Yousem, Bruce A. Wasserman, Colin Wu, Warren Bilker and Norman J. Beauchamp
American Journal of Neuroradiology May 2003, 24 (5) 872-877;
Lukasz S. Babiarz
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David M. Yousem
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Bruce A. Wasserman
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Colin Wu
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Warren Bilker
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Norman J. Beauchamp Jr.
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Article Figures & Data

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  • Fig 1.
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    Fig 1.

    CT calcification scores.

    A, Circumferential nature of cavernous carotid artery calcification on this CT scan, filmed in a bone window, warrants a grade of 4 (360 degrees of involvement).

    B, If the calcification is between 90 and 270 degrees of involvement, it is graded as a 3. The thickness of the calcification, judged by the centimeter scale, was 2 mm in this case.

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    Fig 2.

    MR imaging white matter disease (arrows) scores. All images obtained through white matter were reviewed by using fluid-attenuated inversion recovery imaging before grades were assigned.

    A, This patient was judged to have minimal disease (CHS grade 1).

    B, This patients was assigned a CHS score of 4.

    C, This patient was assigned a CHS score of 7.

Tables

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    TABLE 1:

    Grading scales used

    Extent of calcification of cavernous carotid artery
     Grade 0No calcification
        1Dot of calcification
        2Crescentic area of calcification <90 degrees of carotid wall circumference
        3Calcification from 90–270 degrees circumference
        4Calcification 270–360 degrees around carotid circumference
    Thickness of calcification of cavernous carotid artery
     Grade 0No calcification
        1Calcification 1 mm thick
        2Calcification 2 mm thick
        3Calcification 3 mm thick
        4Calcification >3 mm thick
    White matter disease on fluid-attenuated inversion recovery MR images
     Grade 0No white matter signal abnormalities
        1Discontinuous PV rim or minimal “dot” of SC disease
        2Thin continuous PV rim or few patches of SC disease
        3Thicker continuous PV rim with scattered patches of SC disease
        4Thicker shaggier periventricular rim and mild SC disease
        5Mild PV confluence surrounding the frontal and occipital horns
        6Moderate PV confluence surrounding the frontal and occipital horns
        7PV confluence with moderate involvement of the centrum semiovale
        8PV confluence involving most of the centrum semiovale
        9All supratentorial white matter involved (excluding the corpus callosum)
    • Note.—PV indicates periventricular; SC, subcortical.

    • View popup
    TABLE 2:

    Summary of CT scores

    CT ScoreCT ThicknessNumber of ParticipantsMedian Age (yr) of Participants25th Percentile of Age, 75th Percentile of Age
    0N/A6851.545.0, 60.0
    113862.052.0, 73.0
    12573.052.0, 75.0
    13270.567.0, 74.0
    1All4564.052.0, 73.0
    211467.056.0, 74.0
    221062.553.0, 72.0
    23365.565.0, 66.0
    2All2766.053.0, 72.0
    311668.054.5, 75.0
    32769.065.0, 75.0
    33674.570.0, 79.0
    3All2970.064.0, 75.0
    41870.565.5, 76.0
    42779.072.0, 88.0
    43183.0N/A
    44285.079.0, 91.0
    4All1877.569.0, 82.0
    AllN/A18762.049.0, 73.0
    • View popup
    TABLE 3:

    Summary of MR imaging scores

    MR Imaging ScoreNumber of ParticipantsMedian Age (yr) of Participants25th Percentile of Age, 75th Percentile of Age
    04046.543.0, 55.0
    12659.553.0, 67.5
    23259.050.0, 75.0
    32263.049.0, 72.0
    41064.562.0, 73.0
    51965.059.0, 74.0
    62073.066.5, 79.0
    71773.067.0, 79.0
    8176.0N/A
    All18762.049.0, 73.0
    • View popup
    TABLE 4:

    Spearman correlation scores

    TestSpearman Correlation, No Age AdjustmentSpearman Correlation, with Age Adjustment
    CT grade and MR imaging score0.33 (P < .001)0.016 (P = .83)
    CT thickness and MR imaging score0.27 (P < .001)0.045 (0 = .53)
    Composite grade and thickness and MR imaging score0.31 (P < .0001)0.013 (P = .86)
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American Journal of Neuroradiology: 24 (5)
American Journal of Neuroradiology
Vol. 24, Issue 5
1 May 2003
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Cite this article
Lukasz S. Babiarz, David M. Yousem, Bruce A. Wasserman, Colin Wu, Warren Bilker, Norman J. Beauchamp
Cavernous Carotid Artery Calcification and White Matter Ischemia
American Journal of Neuroradiology May 2003, 24 (5) 872-877;

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Cavernous Carotid Artery Calcification and White Matter Ischemia
Lukasz S. Babiarz, David M. Yousem, Bruce A. Wasserman, Colin Wu, Warren Bilker, Norman J. Beauchamp
American Journal of Neuroradiology May 2003, 24 (5) 872-877;
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