Heterogeneity of Cerebral Blood Flow in Alzheimer Disease and Vascular Dementia

References

1. ↵
   Frackowiak RS, Pozzilli C, Legg NJ, et al. Regional cerebral oxygen supply and utilization in dementia: a clinical and physiological study with oxygen-15 and positron tomography. Brain 1981;104:753–778

   CrossRefPubMed
2. ↵
   Mielke R, Pietrzyk U, Jacobs A, et al. HMPAO SPECT and FDG PET in Alzheimer disease and vascular dementia: comparison of perfusion and metabolic pattern. Eur J Nucl Med 1994;21:1052–1060

   PubMed
3. ↵
   Foster NL, Chase TN, Fedio P, et al. Alzheimer disease: focal cortical changes shown by positron emission tomography. Neurology 1983;33:961–965

   Abstract/FREE Full Text
4. Haxby JV, Gray CL, Koss E, et al. Longitudinal study of cerebral metabolic asymmetries and associated neuropsychological patterns in early dementia of the Alzheimer type. Arch Neurol 1990;47:753–760

   CrossRefPubMedWeb of Science
5. Jagust WJ, Friedland RP, Budinger TF, et al. Longitudinal studies of regional cerebral metabolism in Alzheimer disease. Neurology 1988;38:909–912

   Abstract/FREE Full Text
6. ↵
   Holman BL, Johnson KA, Gerada B, et al. The scintigraphic appearance of Alzheimer disease: a prospective study using technetium-99m-HMPAO SPECT. J Nucl Med 1992;33:181–185

   Abstract/FREE Full Text
7. ↵
   Ishii K, Sasaki M, Kitagaki H, et al. Reduction of cerebellar glucose metabolism in advanced Alzheimer disease. J Nucl Med 1997;38:925–928

   Abstract/FREE Full Text
8. ↵
   Bonte FJ, Weiner MF, Bigio EH, et al. Brain blood flow in the dementias: SPECT with histopathologic correlation in 54 patients. Radiology 1997;202:793–797

   CrossRefPubMedWeb of Science
9. ↵
   Minoshima S, Giordani B, Berent S, Frey KA, Foster NL, Kuhl DE. Metabolic reduction in the posterior cingulate cortex in very early Alzheimer disease. Ann Neurol 1997;42:85–94

   CrossRefPubMedWeb of Science
10. ↵
    Yao H, Sadoshima S, Kuwabara Y, Ichiya Y, Fujishima M. Cerebral blood flow and oxygen metabolism in patients with vascular dementia of the Binswanger type. Stroke 1990;21:1694–1699

    Abstract/FREE Full Text
11. ↵
    Deutsch G, Tweedy JR. Cerebral blood flow in severity-matched Alzheimer and multi-infarct patients. Neurology 1987;37:431–438

    Abstract/FREE Full Text
12. ↵
    Jagust WJ, Bundinger TF, Reed BR. The diagnosis of dementia with single photon emission computed tomography. Arch Neurol 1987;44:258–262

    CrossRefPubMedWeb of Science
13. ↵
    Starkstein SE, Sabe L, Vazquez S, et al. Neuropsychological, psychiatric, and cerebral blood flow findings in vascular dementia and Alzheimer disease. Stroke 1996;27:408–414

    Abstract/FREE Full Text
14. ↵
    Wolfe N, Linn R, Babikian VL, Knoefel JE, Albert ML. Frontal systems impairment following multiple lacunar infarcts. Arch Neurol 1990;47:129–132

    CrossRefPubMedWeb of Science
15. ↵
    Minoshima S, Frey KA, Koeppe RA, Foster NL, Kuhl DE. A diagnostic approach in Alzheimer disease using three-dimensional stereotactic surface projections of fluorine-18-FDG PET. J Nucl Med 1995;36:1238–1248

    Abstract/FREE Full Text
16. ↵
    Kuikka JT, Tiihonen J, Karhu J, et al. Fractal analysis of striatal dopamine re-uptake sites. Eur J Nucl Med 1997;24:1085–1090

    PubMedWeb of Science
17. ↵
    Mandebrot BB. Fractal geometry of nature. San Francisco: W. H. Freeman and Company;1982 :131–137
18. ↵
    Weibel ER. Fractal geometry: a design principle for living organisms. Am J Physiol 1991;261:361–369
19. ↵
    Kuikka JT, Bassingthwaighte JB, Henrich MM, Feinendegen LE. Mathematical modeling in nuclear medicine. Eur J Nucl Med 1991;18:351–362

    CrossRefPubMed
20. ↵
    Kuikka JT, Yang J, Karhu J, et al. Imaging the structure of the striatum: a fractal approach to SPECT image interpretation. Physiol Meas 1998;19:367–374

    CrossRefPubMed
21. ↵
    Bassingthwaighte JB, King RB, Roger SA. Fractal nature of regional myocardial blood flow heterogeneity. Circ Res 1989;65:578–590

    Abstract/FREE Full Text
22. Barman SA, McCloud LL, Catravas JD, Ehrhart IC. Measurement of pulmonary blood flow by fractal analysis of flow heterogeneity in isolated canine lungs. J Appl Physiol 1996;81:2039–2045

    PubMedWeb of Science
23. ↵
    Nagao M, Murase K, Kikuchi T, et al. Fractal analysis of cerebral blood flow distribution in Alzheimer disease. J Nucl Med 2001;42:1446–1450

    Abstract/FREE Full Text
24. ↵
    Tatemichi TK, Desmond DW, Paik M, et al. Clinical determinants of dementia related to stroke. Ann Neurol 1993;33:568–575

    CrossRefPubMedWeb of Science
25. ↵
    Meyer JS, Xu G, Thornby J, Chowdhury MH, Quach M. Is mild cognitive impairment prodromal for vascular dementia like Alzheimer disease? Stroke 2002;33:1981–1985

    Abstract/FREE Full Text
26. ↵
    McKhann G, Drachman D, Folstein M, et al. Clinical diagnosis of Alzheimer disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer disease. Neurology 1984;34:939–944

    Abstract/FREE Full Text
27. ↵
    Roman GC, Tatemichi TK, Erkinjuntti T, et al. Vascular dementia: diagnostic criteria for research studies: report of the NINDS-AIREN International Workshop. Neurology 1993;43:250–260

    Abstract/FREE Full Text
28. ↵
    Erkinjuntti T, Inzitari D, Pantoni L, et al. Research criteria for subcortical vascular dementia in clinical trials. J Neural Transm Suppl 2000;59:23–30

    PubMed
29. ↵
    Folstein MF, Folstein SE, McHugh PR. “Mini-mental state”: a practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 1975;12:189–198

    CrossRefPubMedWeb of Science
30. ↵
    Kimura K, Hashikawa K, Etani H, et al. A new apparatus for brain imaging: four-head rotating gamma camera single photon emission computed tomograph. J Nucl Med 1990;31:603–609

    Abstract/FREE Full Text
31. ↵
    Talairach J, Tournoux P: Co-planar stereotaxic atlas of the human brain, three-dimensional proportional system: an approach to cerebral imaging. New York: translated by Rayport M. Thieme Medical Publishers, Inc.;1988
32. ↵
    Minoshima S, Koeppe RA, Frey KA, et al. Anatomic standardization: linear scaling and nonlinear warping of functional brain images. J Nucl Med 1994;35:1528–1537

    Abstract/FREE Full Text
33. ↵
    Nelson T. Fractal physiologic complexity, scaling, and opportunities for imaging. Invest Radiol 1990;25:1140–1148

    PubMed
34. ↵
    Loeb C, Gandolfo C, Croce R, Conti M. Dementia associated with lacunar infarction. Stroke 1992;23:1225–1229

    Abstract/FREE Full Text
35. ↵
    Hatazawa J, Shimosegawa E, Satoh T, Toyoshima H, Okudera T. Subcortical hypoperfusion associated with asymptomatic white matter lesions on magnetic resonance imaging. Stroke 1997;28:1944–1947

    Abstract/FREE Full Text
36. ↵
    The Lund and Manchester Groups. Clinical and neuropathological criteria for frontotemporal dementia. J Neurol Neurosurg Psychiatry 1994;57:416–418

    FREE Full Text
37. ↵
    Snowdon DA, Greiner LH, Mortimer JA, et al. Brain infarction and the clinical expression of Alzheimer disease: the nun study. JAMA 1997;277:813–817

    CrossRefPubMedWeb of Science
38. ↵
    Ritchie K, Touchon J. Mild cognitive impairment:conceptual basis and current nosological status. Lancet 2000;355:225–228

    CrossRefPubMedWeb of Science
39. ↵
    Kogure D, Matsuda H, Ohnishi T, et al. Longitudinal evaluation of early Alzheimer disease using brain perfusion SPECT. J Nucl Med 2000;41:1155–1162

    Abstract/FREE Full Text
40. ↵
    Herhoz K, Schopphoff H, Schmidt M, et al. Direct comparison of spatially normalized PET and SPECT scans in Alzheimer disease. J Nucl Med 2002;43:21–26

    Abstract/FREE Full Text
41. ↵
    Yoshikawa T, Murase K, Oku N, et al. Statistical image analysis of cerebral blood flow in vascular dementia with small vessel disease. J Nucl Med 2003;44:505–511

    Abstract/FREE Full Text
42. ↵
    Kuikka JT, Hartikainen P. Heterogeneity of cerebral blood flow: a fractal approach. Nuklearmedizin 2000;39:37–42

    PubMed