Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleBrain

Diffusion Tensor Imaging as Potential Biomarker of White Matter Injury in Diffuse Axonal Injury

Thierry A.G.M. Huisman, Lee H. Schwamm, Pamela W. Schaefer, Walter J. Koroshetz, Neetha Shetty-Alva, Yelda Ozsunar, Ona Wu and A. Gregory Sorensen
American Journal of Neuroradiology March 2004, 25 (3) 370-376;
Thierry A.G.M. Huisman
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lee H. Schwamm
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Pamela W. Schaefer
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Walter J. Koroshetz
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Neetha Shetty-Alva
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Yelda Ozsunar
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ona Wu
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Gregory Sorensen
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Gean AD. White matter shearing injury and brainstem. injury In: Imaging of Head Trauma. New York: Raven,1994 :207–248
  2. Murray JG, Gean AD, Evans SJ. Imaging of acute head injury. Semin Ultrasound CT MR. 1996;17:185–205
    CrossRefPubMed
  3. ↵
    Gentry LR. Head trauma. In: Atlas SW, ed. Magnetic Resonance Imaging of the Brain and Spine. New York: Raven,1996;611–647
  4. ↵
    Strich SJ. Shearing of nerve fibres as a cause of brain damage due to head injury: a pathological study of twenty cases. Lancet 1961;2:443–448
  5. ↵
    Adams JH, Graham DI, Murray LS, Scott G. Diffuse axonal injury due to nonmissile head injury in humans: an analysis of 45 cases. Ann Neurol 1982;12:557–563
    CrossRefPubMedWeb of Science
  6. ↵
    Gentry LR, Godersky JC, Thompson B, Dunn VD. Prospective comparative study of intermediate-field MR and CT in the evaluation of closed head trauma. AJR Am J Roentgenol 1988;150:673–682
    PubMedWeb of Science
  7. ↵
    Kelly AB, Zimmerman RD, Snow RB, et al. Head trauma: comparison of MR and CT-experience in 100 patients. AJNR Am J Neuroradiol 1988;9:699–708
    Abstract/FREE Full Text
  8. ↵
    Gale SD, Johnson SC, Bigler ED, Blatter DD. Trauma-induced degenerative changes in brain injury: a morphometric analysis of three patients with preinjury and postinjury MR scans. J Neurotrauma 1995;12:151–158
    PubMedWeb of Science
  9. ↵
    Anderson CV, Wood DM, Bigler ED, Blatter DD. Lesion volume, injury severity, and thalamic integrity following head injury. J Neurotrauma 1996;13:59–65
    PubMed
  10. ↵
    Liu AY, Maldjian JA, Bagley LJ, Sinson GP, Grossman RI. Traumatic brain injury: diffusion-weighted MR imaging findings. AJNR Am J Neuroradiol 1999;20:1636–1641
    Abstract/FREE Full Text
  11. ↵
    Arfanakis K, Haughton VM, Carew JD, Rogers BP, Dempsey RJ, Meyerand ME. Diffusion tensor MR imaging in diffuse axonal injury. AJNR Am J Neuroradiol 2002;23:794–802
    Abstract/FREE Full Text
  12. ↵
    Huisman TAGM, Sorensen AG, Hergan K, Gonzalez RG, Schaefer PW. Diffusion-weighted imaging for the evaluation of diffuse axonal injury in closed head injury. J Comput Assist Tomogr 2003;27:5–11
    CrossRefPubMedWeb of Science
  13. ↵
    Pierpaoli C, Jezzard P, Basser PJ, et al. Diffusion tensor MR imaging of the human brain. Radiology 1996;201:637–648
    PubMedWeb of Science
  14. ↵
    Melhem ER, Itoh R, Jones L, Barker PB. Diffusion tensor MR imaging of the brain: Effect of diffusion weighting on trace and anisotropy measurements. AJNR Am J Neuroradiol 2000;21:1813–1820
    Abstract/FREE Full Text
  15. ↵
    Pfefferbaum A, Sullivan EV, Hedehus M, Lim KO, Adalsteinsson E, Moseley M. Age-related decline in brain white matter anisotropy measured with spatially corrected echo-planar diffusion tensor imaging. Magn Reson Med 2000;44:259–268
    CrossRefPubMedWeb of Science
  16. ↵
    Papadakis NG, Martin KM, Mustafa MH, et al. Study of the effect of CSF suppression on white matter diffusion anisotropy mapping of healthy human brain. Magn Reson Med 2002;38:394–398
  17. ↵
    Sorensen AG, Wu O, Copen WA, et al. Human acute cerebral ischemia: detection of changes in water diffusion anisotropy by using MR imaging. Radiology 1999;212:785–792
    CrossRefPubMedWeb of Science
  18. ↵
    Basser PJ, Pierpaoli C. Microstructural and physiological features of tissues elucidated by quantitative-diffusion-tensor MRI. J Magn Reson B 1996;111:209–219
    CrossRefPubMedWeb of Science
  19. ↵
    Pierpaoli C, Basser PJ. Toward a quantitative assessment of diffusion anisotropy. Magn Reson Med 1996;36:893–906
    CrossRefPubMedWeb of Science
  20. ↵
    Lai SM, Duncan PW. Evaluation of the American Heart Association Stroke Outcome Classification. Stroke 1999;30:1840–1843
    Abstract/FREE Full Text
  21. ↵
    Sinson G, Bagley LJ, Cecil KM, et al. Magnetization transfer imaging and proton MR spectroscopy in the evaluation of axonal injury: Correlation with clinical outcome after traumatic brain injury. AJNR Am J Neuroradiol 2001;22:143–151
    Abstract/FREE Full Text
  22. ↵
    Wieshmann UC, Symms MR, Clark CA, et al. Blunt-head trauma associated with widespread water-diffusion changes. Lancet 1999;10:353:1242–1243
  23. Ulug AM, Moore DF, Bojko AS, Zimmerman RD. Clinical use of diffusion-tensor imaging for diseases causing neuronal and axonal damage. AJNR Am J Neuroradiol 1999;20:1044–1048
    Abstract/FREE Full Text
  24. ↵
    Wieshmann UC, Clark CA, Symms MR, et al. Reduced anisotropy of water diffusion in structural cerebral abnormalities demonstrated with diffusion tensor imaging. Magn Reson Imaging 1999;17:1269–1274
    CrossRefPubMedWeb of Science
  25. ↵
    Brain Trauma Foundation. The American Association of Neurological Surgeons: The joint section on neurotrauma and critical care—Glasgow coma scale score. J Neurotrauma 2000;17:563–571
    PubMed
  26. ↵
    Yang Q, Tress BM, Barber PA, et al. Serial study of apparent diffusion coefficient and anisotropy in patients with acute stroke. Stroke 1999;30:2382–2390
    Abstract/FREE Full Text
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 25 (3)
American Journal of Neuroradiology
Vol. 25, Issue 3
1 Mar 2004
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Diffusion Tensor Imaging as Potential Biomarker of White Matter Injury in Diffuse Axonal Injury
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Thierry A.G.M. Huisman, Lee H. Schwamm, Pamela W. Schaefer, Walter J. Koroshetz, Neetha Shetty-Alva, Yelda Ozsunar, Ona Wu, A. Gregory Sorensen
Diffusion Tensor Imaging as Potential Biomarker of White Matter Injury in Diffuse Axonal Injury
American Journal of Neuroradiology Mar 2004, 25 (3) 370-376;

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Diffusion Tensor Imaging as Potential Biomarker of White Matter Injury in Diffuse Axonal Injury
Thierry A.G.M. Huisman, Lee H. Schwamm, Pamela W. Schaefer, Walter J. Koroshetz, Neetha Shetty-Alva, Yelda Ozsunar, Ona Wu, A. Gregory Sorensen
American Journal of Neuroradiology Mar 2004, 25 (3) 370-376;
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Methods
    • Results
    • Discussion
    • Conclusion
    • Acknowledgments
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Multimodal magnetic resonance imaging characterizes clinical outcome in chronic traumatic brain injury
  • Neuroprotective Effects of Naltrexone in a Mouse Model of Post-Traumatic Epilepsy
  • Visual Cortical Area MT Is Required for Development of the Dorsal Stream and Associated Visuomotor Behaviors
  • Visual Cortical Area MT is Required for Development of the Dorsal Stream and Associated Visuomotor Behaviours
  • Mild Traumatic Brain Injury Disrupts Functional Dynamic Attractors of Healthy Mental States
  • Differential Tractography as a Track-Based Biomarker for Neuronal Injury
  • Long-Term White Matter Changes after Severe Traumatic Brain Injury: A 5-Year Prospective Cohort
  • A Decade of DTI in Traumatic Brain Injury: 10 Years and 100 Articles Later
  • Diffusion Tensor Imaging Detected Optic Nerve Injury Correlates with Decreased Compound Action Potentials after Murine Retinal Ischemia
  • Forensic Application of Postmortem Diffusion-Weighted and Diffusion Tensor MR Imaging of the Human Brain in Situ
  • Longitudinal changes of structural connectivity in traumatic axonal injury
  • Diffusion tensor imaging of acute mild traumatic brain injury in adolescents
  • Diffusion Tensor Imaging Reliably Detects Experimental Traumatic Axonal Injury and Indicates Approximate Time of Injury
  • Answering the Call: The Influence of Neuroimaging and Electrophysiological Evidence on Rehabilitation
  • Whole-Brain N-Acetylaspartate: A Marker of the Severity of Mild Head Trauma
  • Proton MR Spectroscopy and MRI-Volumetry in Mild Traumatic Brain Injury
  • Diffusion tensor imaging: Scientific advance, clinical tool, or just a pretty picture?
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Evaluating the Effects of White Matter Multiple Sclerosis Lesions on the Volume Estimation of 6 Brain Tissue Segmentation Methods
  • Quiet PROPELLER MRI Techniques Match the Quality of Conventional PROPELLER Brain Imaging Techniques
  • Predictors of Reperfusion in Patients with Acute Ischemic Stroke
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire