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OtherINTERVENTIONAL

Creation of Four Experimental Aneurysms with Different Hemodynamics in One Dog

Yong Sam Shin, Yasunari Niimi, Yoshikazu Yoshino, Joon K. Song, Michael Silane and Alejandro Berenstein
American Journal of Neuroradiology August 2005, 26 (7) 1764-1767;
Yong Sam Shin
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Yasunari Niimi
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Yoshikazu Yoshino
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Joon K. Song
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Michael Silane
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Alejandro Berenstein
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    Fig 1.

    Schematic of the four aneurysms surgically created in one dog. A indicates arterial-stump aneurysm; B, bifurcation aneurysm; C, side-wall aneurysm; and D, small branch-artery aneurysm. CTA indicates cranial thyroid artery; SCA, subclavian artery; and VA, vertebral artery.

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    Fig 2.

    Digital subtraction angiogram shows the innominate artery. Left CCA is ligated proximally and divided just above the proximal ligature. Stump of the left CCA is shown as an aneurysmal pouch (asterisk).

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    Fig 3.

    Bifurcation aneurysm is created by using a venous pouch of external jugular vein after a partial end-to-side anastomosis of the left CCA to the proximal part of the arteriotomy of the right CCA. Side-wall aneurysm is created by using a venous pouch of the external jugular vein with slight oblique orientation, and a small branch-artery aneurysm is created by using a venous pouch of the anterior facial vein at the junction of the CCA and cranial thyroid artery (asterisk).

    A, Intraoperative view.

    B, Digital subtraction image.

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    TABLE 1:

    Characteristics of the four aneurysms created in one dog

    AneurysmOperation MethodPouchDiameter (mm)Aneurysm Simulateda
    Arterial-stumpDivision of L CCA, far proximalCCA stump (artery)≤10 to 10–25Any sidewall or terminal-artery aneurysm
    BifurcationSide-to-end anastomosis CCA to ipsilateral CCA, plus aneurysmal pouchVein/artery≤10 to 10–25Basilar apex, MCA bifurcation, terminal ICA, other
    Side-wallCCA plus aneurysmal pouchVein/artery≤10 to 10–25ICA aneurysm (eg, paraopthalmic), supraclinoid segment
    Side branch-arteryCCA, cranial thyroidal branch; junction plus aneurysm pouchFacial vein or artery≤10SCA, AICA, PICA aneurysm, other small aneurysm
    • a AICA indicates anterior inferior cerebellar artery; ICA, internal carotid artery; MCA, middle cerebral artery; PICA, posterior inferior cerebellar artery; and SCA, superior cerebellar artery.

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    TABLE 2:

    Estimated comparative 90-day costs ($) for four aneurysms in two models

    Quadruple ModelIndividual Modela
    Per animal971.803387.20
    90-day maintaintenanceb1080.004320.00
    Surgery2161.502161.50
    Angiography970.503882.00
    Total5183.8014250.70
    • a Four animals, one aneurysm per animal.

    • b At $12/day.

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American Journal of Neuroradiology: 26 (7)
American Journal of Neuroradiology
Vol. 26, Issue 7
1 Aug 2005
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Cite this article
Yong Sam Shin, Yasunari Niimi, Yoshikazu Yoshino, Joon K. Song, Michael Silane, Alejandro Berenstein
Creation of Four Experimental Aneurysms with Different Hemodynamics in One Dog
American Journal of Neuroradiology Aug 2005, 26 (7) 1764-1767;

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Creation of Four Experimental Aneurysms with Different Hemodynamics in One Dog
Yong Sam Shin, Yasunari Niimi, Yoshikazu Yoshino, Joon K. Song, Michael Silane, Alejandro Berenstein
American Journal of Neuroradiology Aug 2005, 26 (7) 1764-1767;
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  • Article
    • Abstract
    • Technique
    • Arterial-Stump Aneurysm
    • Bifurcation Aneurysm
    • Side-Wall Aneurysm
    • Small Branch-Artery Aneurysm
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  • Creation of Large Elastase-Induced Aneurysms: Presurgical Arterial Remodeling Using Arteriovenous Fistulas
  • In Vivo Experimental Intracranial Aneurysm Models: A Systematic Review
  • Asymmetric Vascular Stent: Feasibility Study of a New Low-Porosity Patch-Containing Stent
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