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OtherHEAD AND NECK

Chondrosarcoma of the Hyoid Bone: Imaging, Surgical, and Histopathologic Correlation

S. Hirunpat, K. Prueganusak, Y. Sinruk and W. Tanomkiat
American Journal of Neuroradiology January 2006, 27 (1) 123-125;
S. Hirunpat
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K. Prueganusak
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Y. Sinruk
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W. Tanomkiat
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    Fig 1.

    An inhomogeneous solid echoic mass within the submental area, slightly more prominent on the left side.

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    Fig 2.

    A, Contrast-enhanced axial CT scan at the level of hyoid bone revealed a well- defined mixed attenuation mass that has expanded to the left lesser cornu and has replaced the normal body of the hyoid bone with peripheral rim calcification and internal chondroid calcification. The right lesser cornu cannot be demonstrated.

    B, Contrast-enhanced coronal CT scan revealed a round well-defined inhomogeneous attenuation mass with peripheral rim calcification and internal chondroid calcification below the floor of the mouth.

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    Fig 3.

    A, The surgical specimen revealed a well-defined, almost-round mass originated from the body, both lesser cornua of the hyoid bone, more prominent on the left side The appearance was concordant with the CT finding.

    B, The cut surface of the resected specimen revealed an encapsulated firm, gray-white tissue tumor measuring 7 cm in diameter.

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    Fig 4.

    Histopathology revealed grade 1 chondrosarcoma seen as mature chondrocytes with minimal nuclear and cytoplasmic atypia.

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  • Histological grades of chondrosarcoma28 in correlation with 5-year survival rate29

    GradeHistology5-Year Survival Rate (%)
    1Lesion exhibits a preponderance of small, densely stained nuclei90
    2Lesion contains areas with moderate-sized nuclei but with a low mitotic rate81
    3Lesion has large nuclei, with foci of dense cellularity and a high mitotic rate43
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American Journal of Neuroradiology: 27 (1)
American Journal of Neuroradiology
Vol. 27, Issue 1
January, 2006
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S. Hirunpat, K. Prueganusak, Y. Sinruk, W. Tanomkiat
Chondrosarcoma of the Hyoid Bone: Imaging, Surgical, and Histopathologic Correlation
American Journal of Neuroradiology Jan 2006, 27 (1) 123-125;

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Chondrosarcoma of the Hyoid Bone: Imaging, Surgical, and Histopathologic Correlation
S. Hirunpat, K. Prueganusak, Y. Sinruk, W. Tanomkiat
American Journal of Neuroradiology Jan 2006, 27 (1) 123-125;
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  • Chondrosarcoma of the hyoid bone: a case of mistaken identity in the submandibular region
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