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Research ArticleBRAIN

Technetium Tc-99m Ethyl Cysteinate Dimer Brain Single-Photon Emission CT in Mild Traumatic Brain Injury: A Prospective Study

N.K. Gowda, D. Agrawal, C. Bal, N. Chandrashekar, M. Tripati, G.P. Bandopadhyaya, A. Malhotra and A.K. Mahapatra
American Journal of Neuroradiology February 2006, 27 (2) 447-451;
N.K. Gowda
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D. Agrawal
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C. Bal
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N. Chandrashekar
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M. Tripati
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G.P. Bandopadhyaya
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A. Malhotra
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A.K. Mahapatra
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    Fig 1.

    Comparison of SPECT and CT in patients with mild traumatic brain injury.

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    Fig 2.

    SPECT (A) showing hypoperfusion in left frontal lobe in an 8-year-old male patient with normal plain head CT (B).

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    Table 1:

    Distributions of brain lesions seen in SPECT following MTBI

    Total
    SPECT+CT+
    Frontal lobe27 (42.2%)10 (35.7%)37 (40.2%)14 (15.3%)
    Temporal lobes22 (34.4%)12 (43%)34 (37%)11 (12%)
    Basal ganglia and thalamus21 (33%)10 (28.6%)31 (33.7%)4 (4.4%)
    Parietal lobes6 (9.4%)2 (7.1%)8 (8.7%)5 (5.4%)
    Cerebellum4 (6.3%)1 (3.6%)5 (5.4%)2 (2.2%)
    Occipital lobes3 (4.7%)1 (3.6%)4 (4.4%)2 (2.2%)
    • Note.— SPECT indicates single-photon emission computed tomography; MTBI, mild traumatic brain injury.

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    Table 2:

    Comparison of SPECT and CT findings in patients with PTA, LOC, and PCS

    PTA+PTA−LOC+LOC−PCS+PCS−
    No. of patients306251412666
    SPECT+24 (80%)34 (54.8%)38 (74.5%)20 (48.8%)22 (84.6%)36 (54.6%)
    CT+13 (43.3%)18 (29%)24 (47.1%)7 (17.1%)14 (53.9%)17 (25.8%)
    SPECT lesions
        Temporal lobe19 (63.3%)15 (24.2%)22 (43.1%)12 (29.3%)18 (69.2%)16 (24.2%)
        Frontal lobe14 (46.7%)23 (37.1%)26 (51%)11 (26.8%)12 (46.2%)25 (37.9%)
        Basal ganglia and thalamus11 (36.7%)20 (32.3%)21 (41.2%)11 (26.8%)12 (46.2%)19 (28.9%)
    • Note.— SPECT indicates single-photon emission computed tomography; PTA, posttraumatic amnesia; LOC, Loss of consciousness; PCS, postconcussional syndrome.

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    Table 3:

    Number of patients showing SPECT- and CT-positive findings compared to duration of injury

    Duration between Head Injury and SPECT Imaging
    <24 h24–48 h48–72 h
    No. of patients302636
    SPECT+171625
    CT+ (all patients were imaged within 12 h of injury)10714
    • Note.— SPECT indicates single-photon emission computed tomography.

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    Table 4:

    Number of patients showing SPECT- and CT-positive findings compared to GCS

    Glasgow Coma Score
    131415
    No. of patients122555
    SPECT+111830
    CT+81211
    • Note.— SPECT indicates single-photon emission computed tomography.

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American Journal of Neuroradiology: 27 (2)
American Journal of Neuroradiology
Vol. 27, Issue 2
February, 2006
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Cite this article
N.K. Gowda, D. Agrawal, C. Bal, N. Chandrashekar, M. Tripati, G.P. Bandopadhyaya, A. Malhotra, A.K. Mahapatra
Technetium Tc-99m Ethyl Cysteinate Dimer Brain Single-Photon Emission CT in Mild Traumatic Brain Injury: A Prospective Study
American Journal of Neuroradiology Feb 2006, 27 (2) 447-451;

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Technetium Tc-99m Ethyl Cysteinate Dimer Brain Single-Photon Emission CT in Mild Traumatic Brain Injury: A Prospective Study
N.K. Gowda, D. Agrawal, C. Bal, N. Chandrashekar, M. Tripati, G.P. Bandopadhyaya, A. Malhotra, A.K. Mahapatra
American Journal of Neuroradiology Feb 2006, 27 (2) 447-451;
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