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Research ArticleINTERVENTIONAL

Diffusion-Weighted MR Imaging in Carotid Angioplasty and Stenting with Protection by the Reversed Carotid Arterial Flow

F. Asakura, K. Kawaguchi, H. Sakaida, N. Toma, S. Matsushima, K. Kuraishi, H. Tanemura, Y. Miura, M. Maeda and W. Taki
American Journal of Neuroradiology April 2006, 27 (4) 753-758;
F. Asakura
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K. Kawaguchi
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H. Sakaida
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N. Toma
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S. Matsushima
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K. Kuraishi
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H. Tanemura
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Y. Miura
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M. Maeda
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W. Taki
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  • Fig 1.
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    Fig 1.

    Schema of the procedure by using the Parodi Anti-Emboli System. STA, superior thyroid artery; FA, facial artery; arrow, reversed blood flow; double arrow, normal blood flow; spot, debris

    A, Flow reversal from the intracranial ICA by blockade of both the proximal CCA and ECA.

    B, Placement of stent.

    C, Postdilation.

    D, Irrigation of debris by flow reversal.

    E, Return to normal flow.

    F, Final

  • Fig 2.
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    Fig 2.

    Carotid angioplasty with stent by Parodi Anti-Emboli System (left carotid angiogram, anteroposterior and lateral view). White arrow, blocking balloon in the external carotid artery; black arrow, proximal blocking balloon in the common carotid artery.

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    Fig 3.

    Ischemic lesions after carotid angioplasty with stent by Parodi Anti-Emboli System (diffusion-weighted MR image).

    Top, Case 8 (after left carotid stent placement).

    Bottom, Case 9 (after left carotid stent placement).

Tables

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    Table 1:

    Patients undergoing carotid angioplasty with stenting using the Parodi Anti-Emboli System in Mie University Hospital from 2003 to 2004

    Patient No./Age (y)/SexSideSymptom before TreatmentSystemic ComplicationStenosis Ratio (%)Postprocedural Stenosis (%)Occlusion Time during Procedure (s)Control ACT (s)ACT during Procedure (s)Prolonged ACT timesPredilationStentMRI-DWI Findings after Procedure (High-Signal Spot)
    1/71/MRAsymptomaticHTN90104181482221.50(−)SMARTeR(−)
    2/88/MLTIAHTN90306601503182.12(+)SMARTeR(−)
    3/69/MRAsymptomaticDM, HL90159641613041.89(+)SMARTeR(−)
    4/75/MRTIA (Amaurosis)DM90106831513892.58(+)SMARTeR(−)
    5/62/MRMinor(−)80156001382862.07(+)SMARTeR(−)
    6/69/MLMinorHL9054201332501.88(−)SMARTeR(−)
    7/61/MRAsymptomaticDM, HTN9008301675233.13(+)SMARTeR(−)
    8/63/MLMajorDVT7056241673442.06(+)SMARTeR(+)
    9/65/MLAsymptomaticHTN, HL70105171373372.46(−)SMARTeR(+)
    10/77/MLMinorCRF, OMI90513541444282.97(+)SMARTeR(−)
    11/66/MRMinorDM9559311102542.31(+)Protege(−)
    • Note:—ACT indicates activated clotting time; MRI-DWI, magnetic resonance imaging–diffusion weighted imaging; TIA, transient ischemia attack; HTN, hypertension; DM, diabetes mellitus; HL, hyperlipidemia; DVT, deep venous thrombosis; CRF, chronic renal failure; OMI, old myocardial infarction.

    • Averages are as follows: age, 69.7 ± 7.8 years; stenosis ratio, 85.4 ± 8.5%; occlusion time, 722.5 ± 255.2 seconds; ACT (control), 146.1 ± 15.2 seconds; ACT (during procedures, 329.5 ± 80.7 seconds.

    • View popup
    Table 2:

    MRI-DWI assessment after DSA in Mie University Hospital from 2002 to 2004 (control group)

    Patient No./Age (y)/SexDiagnosisDSA Study (No. of vessels)MRI-DWI Study after DSAHigh-Intensity Spot on MRI-DWI
    1/71/MBilateral IC stenosis41 day after(−)
    2/46/FUnruptured aneurysm41 day after(+) (1 spot, 2mm)
    3/29/FDural AVF6Same day(−)
    4/31/FBrain tumor36 days after(−)
    5/76/MRight IC stenosis410 days after(−)
    6/39/MBrain tumor41 day after(−)
    7/59/FBrain tumor61 day after(+) (1 spot, 2mm)
    8/56/FBrain tumor4Same day(−)
    9/77/FUnruptured aneurysm41 day after(−)
    10/37/MBrain tumor35 days after(−)
    11/64/MRight IC stenosis43 days after(−)
    12/76/FRight IC stenosis48 days after(−)
    13/77/MLeft IC occlusion4Same day(−)
    14/49/MLeft MC occlusion4Same day(−)
    15/59/FLeft IC occlusion41 day after(−)
    16/76/MRight IC stenosis41 day after(−)
    17/43/FUnruptured aneurysm44 days after(+) (2 spots, 2mm)
    18/58/MLeft IC stenosis410 days after(−)
    19/53/FRight VA dissection41 day after(−)
    20/69/MRight IC stenosis41 day after(−)
    21/48/MUnruptured aneurysm41 day after(−)
    22/71/MRight IC stenosis41 day after(−)
    23/74/MLeft IC stenosis, Right IC occlusion41 day after(−)
    24/74/FUnruptured aneurysm41 day after(−)
    25/59/MLeft VA occlusion41 day after(−)
    26/44/MUnconsciousness due to hypnotics4Same day(−)
    • Note:—MRI-DWI indicates magnetic resonance imaging–diffusion weighted imaging; DSA, digital subtraction angiography; within the DSA study column, 4 vessels, bilateral common carotid arteries and bilateral vertebral arteries, and 6 vessels, bilateral internal and external carotid arteries and bilateral vertebral arteries; IC, internal carotid artery; MC, middle cerebral artery; VA, vertebral artery; AVF, arteriovenous fistula. Average age was 58.3 ± 15.3 years.

    • View popup
    Table 3:

    Newly appearing high-intensity spots after carotid angioplasty with stent on MRI-DWI

    Patient No.SideFindings on MRI-DWI
    PositionNo. of SpotsSize of Spots
    8LeftIpsilateral frontal lobe12 mm
    9LeftIpsilateral frontal lobe32 mm
    • Note:— MRI-DWI indicates magnetic resonance imaging–diffusion weighted imaging.

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American Journal of Neuroradiology: 27 (4)
American Journal of Neuroradiology
Vol. 27, Issue 4
April 2006
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F. Asakura, K. Kawaguchi, H. Sakaida, N. Toma, S. Matsushima, K. Kuraishi, H. Tanemura, Y. Miura, M. Maeda, W. Taki
Diffusion-Weighted MR Imaging in Carotid Angioplasty and Stenting with Protection by the Reversed Carotid Arterial Flow
American Journal of Neuroradiology Apr 2006, 27 (4) 753-758;

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Diffusion-Weighted MR Imaging in Carotid Angioplasty and Stenting with Protection by the Reversed Carotid Arterial Flow
F. Asakura, K. Kawaguchi, H. Sakaida, N. Toma, S. Matsushima, K. Kuraishi, H. Tanemura, Y. Miura, M. Maeda, W. Taki
American Journal of Neuroradiology Apr 2006, 27 (4) 753-758;
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