Research ArticleBRAIN
Whole Brain and Localized Magnetization Transfer Measurements Are Associated with Cognitive Impairment in Patients Infected with Human Immunodeficiency Virus
Y. Wu, P. Storey, A. Carrillo, C. Saglamer, B.A. Cohen, L.G. Epstein, R.R. Edelman and A.B. Ragin
American Journal of Neuroradiology January 2008, 29 (1) 140-145; DOI: https://doi.org/10.3174/ajnr.A0740
Y. Wu
P. Storey
A. Carrillo
C. Saglamer
B.A. Cohen
L.G. Epstein
R.R. Edelman

References
- ↵McArthur JC, Brew BJ, Nath A. Neurological complications of HIV infection. Lancet Neurol 2005;4:543–55
- ↵Kaul M, Garden GA, Lipton SA. Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 2001;410:988–94
- ↵Power C, Gill MJ, Johnson RT. Progress in clinical neurosciences: the neuropathogenesis of HIV infection–host-virus interaction and the impact of therapy. Can J Neurol Sci 2002;29:19–32
- ↵Navia BA, Cho ES, Petito CK, et al. The AIDS dementia complex: II. Neuropathology. Ann Neurol 1986;19:525–35
- ↵
- ↵Navia BA, Jordan BD, Price RW. The AIDS dementia complex: I. Clinical features. Ann Neurol 1986;19:517–24
- ↵Post MJ, Berger JR, Quencer RM. Asymptomatic and neurologically symptomatic HIV-seropositive individuals: prospective evaluation with cranial MR imaging. Radiology 1991;178:131–39
- ↵Koenig SH. Cholesterol of myelin is the determinant of gray-white contrast in MRI of brain. Magn Reson Med 1991;20:285–91
- ↵Dousset V, Brochet B, Vital A, et al. Lysolecithin-induced demyelination in primates: preliminary in vivo study with MR and magnetization transfer. AJNR Am J Neuroradiol 1995;16:225–31
- ↵Wolff SD, Balaban RS. Magnetization transfer contrast (MTC) and tissue water proton relaxation in vivo. Magn Reson Med 1989;10:135–44
- ↵Dousset V, Grossman RI, Ramer KN, et al. Experimental allergic encephalomyelitis and multiple sclerosis: lesion characterization with magnetization transfer imaging. Radiology 1992;182:483–91
- Grossman RI, Gomori JM, Ramer KN, et al. Magnetization transfer: theory and clinical applications in neuroradiology. Radiographics 1994;14:279–90
- ↵Filippi M, Campi A, Dousset V, et al. A magnetization transfer imaging study of normal-appearing white matter in multiple sclerosis. Neurology 1995;45:478–82
- ↵van Buchem MA, Grossman RI, Armstrong C, et al. Correlation of volumetric magnetization transfer imaging with clinical data in MS. Neurology 1998;50:1609–17
- ↵Dousset V, Armand JP, Lacoste D, et al. Magnetization transfer study of HIV encephalitis and progressive multifocal leukoencephalopathy: Groupe d'Epidemiologie Clinique du SIDA en Aquitaine. AJNR Am J Neuroradiol 1997;18:895–901
- ↵van der Flier WM, van den Heuvel DM, Weverling-Rijnsburger AW, et al. Magnetization transfer imaging in normal aging, mild cognitive impairment, and Alzheimer's disease. Ann Neurol 2002;52:62–67
- ↵Ge Y, Kolson DL, Babb JS, et al. Whole brain imaging of HIV-infected patients: quantitative analysis of magnetization transfer ratio histogram and fractional brain volume. AJNR Am J Neuroradiol 2003;24:82–87
- ↵Ragin AB, Storey P, Cohen BA, et al. Disease burden in HIV-associated cognitive impairment: a study of whole-brain imaging measures. Neurology 2004;63:2293–97
- ↵McArthur JC, McDermott MP, McClernon D, et al. Attenuated central nervous system infection in advanced HIV/AIDS with combination antiretroviral therapy. Arch Neurol 2004;61:1687–96
- ↵Price RW, Brew BJ. The AIDS dementia complex. J Infect Dis 1988;158:1079–83
- ↵Marder K, Tang MX, Mejia H, et al. Risk of Parkinson's disease among first-degree relatives: a community-based study. Neurology 1996;47:155–60
- ↵Marder K, Albert SM, McDermott MP, et al. Inter-rater reliability of a clinical staging of HIV-associated cognitive impairment. Neurology 2003;60:1467–73
- ↵Benjamini Y, Drai D, Elmer G, et al. Controlling the false discovery rate in behavior genetics research. Behav Brain Res 2001;125:279–84
- ↵Grossman RI. Application of magnetization transfer imaging to multiple sclerosis. Neurology 1999;53:S8–11
- ↵Hentschel F, Kreis M, Damian M, et al. Quantification of microangiopathic lesions in brain parenchyma and age-adjusted mean scores for the diagnostic separation of normal from pathological values in senile dementia [in German]. Rofo 2005;177:864–71
- ↵van Buchem MA, McGowan JC, Grossman RI. Magnetization transfer histogram methodology: its clinical and neuropsychological correlates. Neurology 1999;53:S23–28
- ↵Rovaris M, Filippi M, Falautano M, et al. Relation between MR abnormalities and patterns of cognitive impairment in multiple sclerosis. Neurology 1998;50:1601–08
- ↵Filley CM. White matter and behavioral neurology. Ann N Y Acad Sci 2005;1064:162–83
- ↵Filippi M, Rocca MA, Martino G, et al. Magnetization transfer changes in the normal-appearing white matter precede the appearance of enhancing lesions in patients with multiple sclerosis. Ann Neurol 1998;43:809–14
- ↵Loevner LA, Grossman RI, Cohen JA, et al. Microscopic disease in normal-appearing white matter on conventional MR images in patients with multiple sclerosis: assessment with magnetization-transfer measurements. Radiology 1995;196:511–15
- ↵Ernst T, Chang L, Witt M, et al. Progressive multifocal leukoencephalopathy and human immunodeficiency virus-associated white matter lesions in AIDS: magnetization transfer MR imaging. Radiology 1999;210:539–43
- ↵Everall I, Barnes H, Spargo E, et al. Assessment of neuronal density in the putamen in human immunodeficiency virus (HIV) infection: application of stereology and spatial analysis of quadrats. J Neurovirol 1995;1:126–29
- ↵Filippi CG, Ulug AM, Ryan E, et al. Diffusion tensor imaging of patients with HIV and normal-appearing white matter on MR images of the brain. AJNR Am J Neuroradiol 2001;22:277–83
- ↵Wu Y, Storey P, Cohen BA, et al. Diffusion alterations in corpus callosum of patients with HIV. AJNR Am J Neuroradiol 2006;27:656–60
- ↵Pfefferbaum A, Rosenbloom MJ, Adalsteinsson E, et al. Diffusion tensor imaging with quantitative fibre tracking in HIV infection and alcoholism comorbidity: synergistic white matter damage. Brain 2007;130:48–64. Epub 2006 Sep 7
- ↵Thompson PM, Dutton RA, Hayashi KM, et al. 3D mapping of ventricular and corpus callosum abnormalities in HIV/AIDS. Neuroimage 2006;2031:2012–23
- ↵Budka H. HIV-associated neuropathology. In: Gendelman HE, Igor, Everall IP, et al, eds. The Neurology of AIDS. New York: Chapman & Hall;1998 :241–60
- ↵Chang L, Lee PL, Yiannoutsos CT, et al. A multicenter in vivo proton-MRS study of HIV-associated dementia and its relationship to age. Neuroimage 2004;23:1336–47
- ↵
- ↵Ragin AB, Wu Y, Storey P, et al. Diffusion tensor imaging of subcortical brain injury in patients infected with human immunodeficiency virus. J Neurovirol 2005;11:292–98
- ↵Vavasour IM, Clark CM, Li DK, et al. Reproducibility and reliability of MR measurements in white matter: clinical implications. Neuroimage 2006;2032:2637–42
- ↵Mesulam M. Brain, mind, and the evolution of connectivity. Brain Cogn 2000;42:4–6
- ↵Reuter-Lorenz, PA. Parallel processing in the bisected brain: implications for callosal function. In: Zaidel E, Iacoboni M, eds. The Parallel Brain: The Cognitive Neuroscience of the Corpus Callosum. Cambridge, Mass; MIT Press;2003
- ↵Inglese M, van Waesberghe JH, Rovaris M, et al. The effect of interferon beta-1b on quantities derived from MT MRI in secondary progressive MS. Neurology 2003;60:853–60
- ↵Filippi M, Dousset V, McFarland HF, et al. The role of MRI in the diagnosis and monitoring of multiple sclerosis: consensus report of the White Matter Study Group. J Magn Reson Imaging 2002;15:499–504
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Y. Wu, P. Storey, A. Carrillo, C. Saglamer, B.A. Cohen, L.G. Epstein, R.R. Edelman, A.B. Ragin
Whole Brain and Localized Magnetization Transfer Measurements Are Associated with Cognitive Impairment in Patients Infected with Human Immunodeficiency Virus
American Journal of Neuroradiology Jan 2008, 29 (1) 140-145; DOI: 10.3174/ajnr.A0740
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Whole Brain and Localized Magnetization Transfer Measurements Are Associated with Cognitive Impairment in Patients Infected with Human Immunodeficiency Virus
Y. Wu, P. Storey, A. Carrillo, C. Saglamer, B.A. Cohen, L.G. Epstein, R.R. Edelman, A.B. Ragin
American Journal of Neuroradiology Jan 2008, 29 (1) 140-145; DOI: 10.3174/ajnr.A0740
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