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Research ArticleBrain

Renal Safety of CT Angiography and Perfusion Imaging in the Emergency Evaluation of Acute Stroke

J.J. Hopyan, D.J. Gladstone, G. Mallia, J. Schiff, A.J. Fox, S.P. Symons, B.H. Buck, S.E. Black and R.I. Aviv
American Journal of Neuroradiology November 2008, 29 (10) 1826-1830; DOI: https://doi.org/10.3174/ajnr.A1257
J.J. Hopyan
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D.J. Gladstone
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G. Mallia
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J. Schiff
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A.J. Fox
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S.P. Symons
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B.H. Buck
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S.E. Black
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R.I. Aviv
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Article Figures & Data

Tables

  • Characteristics for the 5 patients who developed CIN

    CharacteristicsPatients Who Developed CIN
    Patient 1Patient 2Patient 3Patient 4Patient 5
    Age, y7595723485
    GenderFemaleMaleFemaleMaleFemale
    Stroke typeIschemicIschemicHemorrhagicHemorrhagicIschemic
    Risk factors for CIN
        Known history of renal impairmentYes*Yes†NoNoNo
        DiabetesYesNoNoNoYes
    Type of contrast scan and number of scans within 24 hours1 CTA+CTP1 CTA+CTP1 CTA1 CTA1 CTA+CTP
    Creatinine level known at time of contrast CT?YesYesYesYesNo
    GFR day 0, mL/min46426616664
    GFR nadir, mL/min32295213243
    Creatinine levels, μmol/L
        Day 0132102546692
        Day 116795538097
        Day 2189856081133
        Day 31911476883109
    Type of contrastIso-osmolarLow osmolarLow osmolarLow osmolarLow osmolar
    Outcome
        Chronic renal failureNoNoNoNoNo
        DialysisNoNoNoNoNo
    • Note:—CTA indicates CT angiography; CTP, CT perfusion; CIN, contrast-induced nephropathy; GFR, glomerular filtration rate.

    • * Diabetic nephropathy.

    • † Polycystic kidney disease.

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American Journal of Neuroradiology: 29 (10)
American Journal of Neuroradiology
Vol. 29, Issue 10
November 2008
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Cite this article
J.J. Hopyan, D.J. Gladstone, G. Mallia, J. Schiff, A.J. Fox, S.P. Symons, B.H. Buck, S.E. Black, R.I. Aviv
Renal Safety of CT Angiography and Perfusion Imaging in the Emergency Evaluation of Acute Stroke
American Journal of Neuroradiology Nov 2008, 29 (10) 1826-1830; DOI: 10.3174/ajnr.A1257

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Renal Safety of CT Angiography and Perfusion Imaging in the Emergency Evaluation of Acute Stroke
J.J. Hopyan, D.J. Gladstone, G. Mallia, J. Schiff, A.J. Fox, S.P. Symons, B.H. Buck, S.E. Black, R.I. Aviv
American Journal of Neuroradiology Nov 2008, 29 (10) 1826-1830; DOI: 10.3174/ajnr.A1257
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Cited By...

  • Save the Brain First: CTA and Mechanical Thrombectomy in Patients at Risk for Contrast-Induced Nephropathy
  • Management of acute ischemic stroke
  • 2018 Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association
  • Neurons Over Nephrons: Systematic Review and Meta-Analysis of Contrast-Induced Nephropathy in Patients With Acute Stroke
  • Risk of acute kidney injury associated with neuroimaging obtained during triage and treatment of patients with acute ischemic stroke symptoms
  • Response by Ehrlich et al to Letter Regarding Article, "Safety of Computed Tomographic Angiography in the Evaluation of Patients With Acute Stroke: A Single-Center Experience"
  • Safety of Computed Tomographic Angiography in the Evaluation of Patients With Acute Stroke: A Single-Center Experience
  • Multimodal Diagnostic Imaging for Hyperacute Stroke
  • Investigating intracerebral haemorrhage
  • Systematic Review, Critical Appraisal, and Analysis of the Quality of Economic Evaluations in Stroke Imaging
  • Risk of contrast-induced nephropathy in patients undergoing endovascular treatment of acute ischemic stroke
  • CT perfusion improves diagnostic accuracy and confidence in acute ischaemic stroke
  • Computed Tomography Angiography in Hyperacute Ischemic Stroke: Prognostic Implications and Role in Decision-Making
  • Routine pre-procedure laboratory testing for patients undergoing outpatient cerebral angiography is not indicated
  • Defining Intravenous Recombinant Tissue Plasminogen Activator Failure
  • A 5-Item Prediction Rule to Identify Severe Renal Dysfunction in Patients with Acute Stroke
  • Prolonged Carotid Sinus Reflex Is a Risk Factor for Contrast-Induced Nephropathy following Carotid Artery Stenting
  • Safety of performing CT angiography in stroke patients treated with intravenous thrombolysis
  • Functional Contrast-Enhanced CT for Evaluation of Acute Ischemic Stroke Does Not Increase the Risk of Contrast-Induced Nephropathy
  • CT Angiography for Intracerebral Hemorrhage Does Not Increase Risk of Acute Nephropathy
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  • Multimodal CT Provides Improved Performance for Lacunar Infarct Detection
  • Optimal MRI Sequence for Identifying Occlusion Location in Acute Stroke: Which Value of Time-Resolved Contrast-Enhanced MRA?
  • Evaluating the Effects of White Matter Multiple Sclerosis Lesions on the Volume Estimation of 6 Brain Tissue Segmentation Methods
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