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OtherREVIEW ARTICLES

Brain Tumor Imaging in Clinical Trials

J.W. Henson, S. Ulmer and G.J. Harris
American Journal of Neuroradiology March 2008, 29 (3) 419-424; DOI: https://doi.org/10.3174/ajnr.A0963
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Article Information

vol. 29 no. 3 419-424
DOI 
https://doi.org/10.3174/ajnr.A0963
PubMed 
18272557

Published By 
American Journal of Neuroradiology
Print ISSN 
0195-6108
Online ISSN 
1936-959X
History 
  • Published online March 12, 2008.

Copyright & Usage 
Copyright © American Society of Neuroradiology

Author Information

  1. J.W. Hensona,b,c,d,e,f,
  2. S. Ulmera and
  3. G.J. Harrisc,d,f
  1. aStephen E. and Catherine Pappas Brain Tumor Imaging Research Program, Massachusetts General Hospital, Boston, Mass
  2. bDivision of Neuroradiology, Massachusetts General Hospital, Boston, Mass
  3. c3D Imaging Service, Massachusetts General Hospital, Boston, Mass
  4. dDepartment of Radiology, Massachusetts General Hospital, Boston, Mass
  5. eNeurology Service, Massachusetts General Hospital, Boston, Mass
  6. fHarvard Medical School, Boston, Mass
  1. Please address correspondence to John W. Henson, MD, Stephen E. and Catherine Pappas Brain Tumor Imaging Research Program, Massachusetts General Hospital, 55 Fruit St, Yawkey Nine East, Boston, MA 02114; e-mail: henson{at}helix.mgh.harvard.edu
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American Journal of Neuroradiology: 29 (3)
American Journal of Neuroradiology
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Cite this article
J.W. Henson, S. Ulmer, G.J. Harris
Brain Tumor Imaging in Clinical Trials
American Journal of Neuroradiology Mar 2008, 29 (3) 419-424; DOI: 10.3174/ajnr.A0963

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Brain Tumor Imaging in Clinical Trials
J.W. Henson, S. Ulmer, G.J. Harris
American Journal of Neuroradiology Mar 2008, 29 (3) 419-424; DOI: 10.3174/ajnr.A0963
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  • Article
    • Abstract
    • Measurement Techniques
    • Response Criteria
    • Comparison of Diameter and Volumetric Approaches
    • Choosing a Measurable Lesion in Clinical Trials
    • Technical Considerations
    • Timing of Imaging Studies and Confirmation of Response
    • Validity of Imaging End Points in Clinical Trials
    • Challenges with Novel Therapeutics
    • Conclusions
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