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Research ArticleHead and Neck Imaging

Diagnostic Criteria for Spontaneous Spinal CSF Leaks and Intracranial Hypotension

W.I. Schievink, M.M. Maya, C. Louy, F.G. Moser and J. Tourje
American Journal of Neuroradiology May 2008, 29 (5) 853-856; DOI: https://doi.org/10.3174/ajnr.A0956
W.I. Schievink
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M.M. Maya
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C. Louy
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F.G. Moser
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J. Tourje
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    Fig 1.

    Postmyelography CTs showing (A) bilateral cervicothoracic CSF leaks without an associated meningeal diverticulum; B, Left thoracic meningeal diverticulum with an associated CSF leak; and C, right thoracic meningeal diverticulum without an associated CSF leak.

  • Fig 2.
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    Fig 2.

    A, Brain MR images showing typical findings in spontaneous intracranial hypotension with a coronal T2-weighted image showing subdural fluid collections; B, a coronal gadolinium-enhanced T1-weighted image showing enhancement of the pachymeninges; and C, a T1-weighted sagittal image showing sagging of the brain.

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    Table 1:

    Diagnostic criteria for spontaneous spinal CSF leak and intracranial hypotension

    Criterion A, demonstration of a spinal CSF leak (ie, presence of extrathecal CSF),
    or, if criterion A not met:
    Criterion B, cranial MR imaging changes of intracranial hypotension (ie, presence of subdural fluid collections, enhancement of the pachymeninges, or sagging of the brain), and the presence of at least one of the following:
    1. low opening pressure (≤60 mm H2O);

    2. spinal meningeal diverticulum;

    3. improvement of symptoms after epidural blood patching;

    or, if criteria A and B not met:
    Criterion C, the presence of all of the following or at least 2 of the following if typical orthostatic headaches are present:
    1. low opening pressure (≤60 mm H2O),

    2. spinal meningeal diverticulum, and

    3. improvement of symptoms after epidural blood patching.

    • Note:—Patients with onset of symptoms after dural puncture or other penetrating spinal trauma are excluded.

    • View popup
    Table 2:

    Data on 107 patients evaluated for spontaneous spinal CSF leak and intracranial hypotension

    CriterionTotal No. M:FMean Age (SD) RangePositive Brain MR ResultsSpinal Imaging CSF Leak/DiverticulaLow OPResponse to EBP
    Patients meeting diagnostic criteria
        Criterion A7840.6 (12.5)
    30:4812–6157/7878/2860/6472/75
        Criterion B1149.2 (12.3)11/110/75/67/8
    4:734–72
        Criterion C542.8 (6.6)0/50/55/55/5
    2:337–52
        Total9441.7 (12.5)68/9478/4070/7584/88
    36:5812–72
    Patients not meeting diagnostic criteria
    1343.5 (20.3)0/130/01/131/11
    4:913–76
    • Note:—M:F indicates male-to-female ratio; SD, standard deviation; OP, opening pressure; EBP, epidural blood patch.

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American Journal of Neuroradiology: 29 (5)
American Journal of Neuroradiology
Vol. 29, Issue 5
May 2008
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Cite this article
W.I. Schievink, M.M. Maya, C. Louy, F.G. Moser, J. Tourje
Diagnostic Criteria for Spontaneous Spinal CSF Leaks and Intracranial Hypotension
American Journal of Neuroradiology May 2008, 29 (5) 853-856; DOI: 10.3174/ajnr.A0956

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Diagnostic Criteria for Spontaneous Spinal CSF Leaks and Intracranial Hypotension
W.I. Schievink, M.M. Maya, C. Louy, F.G. Moser, J. Tourje
American Journal of Neuroradiology May 2008, 29 (5) 853-856; DOI: 10.3174/ajnr.A0956
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  • The Interpeduncular Angle: A Practical and Objective Marker for the Detection and Diagnosis of Intracranial Hypotension on Brain MRI
  • Quantitative Measurement of CSF in Patients with Spontaneous Intracranial Hypotension
  • False localizing sign of cervico-thoracic CSF leak in spontaneous intracranial hypotension
  • Bariatric surgery as a possible risk factor for spontaneous intracranial hypotension
  • Large-Volume Blood Patch to Multiple Sites in the Epidural Space through a Single-Catheter Access Site for Treatment of Spontaneous Intracranial Hypotension
  • Spinal Meningeal Diverticula in Spontaneous Intracranial Hypotension: Analysis of Prevalence and Myelographic Appearance
  • Distant Subdural and Epidural Hematomas: A Case Report
  • CT-Guided Epidural Blood Patching of Directly Observed or Potential Leak Sites for the Targeted Treatment of Spontaneous Intracranial Hypotension
  • An episode of cerebrospinal fluid leak syndrome involving a marathon runner
  • Diffuse Pachymeningeal Enhancement and Subdural and Subarachnoid Space Opacification on Delayed Postcontrast Fluid-Attenuated Inversion Recovery Imaging in Spontaneous Intracranial Hypotension: Visualizing the Monro-Kellie Hypothesis
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