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Research ArticleBRAIN

Diffuse Pachymeningeal Hyperintensity and Subdural Effusion/Hematoma Detected by Fluid-Attenuated Inversion Recovery MR Imaging in Patients with Spontaneous Intracranial Hypotension

M. Tosaka, N. Sato, H. Fujimaki, Y. Tanaka, K. Kagoshima, A. Takahashi, N. Saito and Y. Yoshimoto
American Journal of Neuroradiology June 2008, 29 (6) 1164-1170; DOI: https://doi.org/10.3174/ajnr.A1041
M. Tosaka
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N. Sato
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H. Fujimaki
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Y. Tanaka
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K. Kagoshima
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A. Takahashi
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N. Saito
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Y. Yoshimoto
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    Fig 1.

    Patient 5. Initial axial, half cut, and magnified MR images of a 39-year-old man with spontaneous intracranial hypotension who presented with a 1-month history of orthostatic headache, nausea, vomiting, and diplopia. Supportive treatment resolved the symptoms. A, T1-weighted image showing diffusely thickened dura mater as isointense. Subdural lesions are unclear. B, T2-weighted image showing that bilateral subdural effusion/hematomas could not be discriminated from CSF. C, T1-weighted image with gadolinium clearly showing diffuse pachymeningeal enhancement. D, FLAIR image showing diffuse pachymeningeal hyperintensity (arrowheads) and very thin bilateral subdural effusion/hematomas in the frontal region (arrow).

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    Fig 2.

    Patient 4. Chronologic FLAIR and T1-weighted MR images of a 37-year-old woman with spontaneous intracranial hypotension. She had a 1-month history of orthostatic headache. Cervical epidural blood patch resolved the symptoms. A, Initial FLAIR image showing diffuse pachymeningeal hyperintensity at the falx, tentorium, and dura of the posterior fossa (arrowheads) and bilateral thick subdural effusion/hematomas (arrows). B, Second FLAIR image performed 1 month after effective blood patch showing disappearance of the diffuse pachymeningeal hyperintensity but thickening of the subdural effusion/hematomas (arrows). C, Follow-up FLAIR image showing remnant subdural effusion/hematomas (arrows). D, Initial T1-weighted image with gadolinium showing DPME at the falx, tentorium, and dura of the posterior fossa (arrowheads) and bilateral thick subdural effusion/hematomas (arrows). E, Second T1-weighted image taken 1 month after completely effective blood patch showing slight remnant of DPME and thickening of the subdural effusion/hematomas (arrows). F, Follow-up T1-weighted image showing remnant subdural effusion/hematomas (arrows).

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    Fig 3.

    Patient 8. Chronologic FLAIR and T1-weighted MR images of a 47-year-old woman with spontaneous intracranial hypotension. She had a 1-week history of orthostatic headache. Lumbar epidural blood patch resolved the symptoms. A, Initial FLAIR image showing diffuse pachymeningeal hyperintensity (arrowheads). B, Second FLAIR image taken 1 week after completely effective blood patch showing thickened diffuse pachymeningeal hyperintensity (arrowheads) and partial subdural effusion/hematomas (arrows). C, Follow-up FLAIR image showing disappearance of the diffuse pachymeningeal hyperintensity and subdural effusion/hematomas. D, Initial T1-weighted image with gadolinium showing DPME (arrowheads). E, Second T1-weighted image taken 1 week after effective blood patch showing disappearance of DPME (arrowheads) and partial subdural effusion/hematomas (arrows). F, Follow-up T1-weighted image showing disappearance of the DPME and subdural effusion/hematomas.

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    Table 1:

    Distribution of diffuse pachymeningeal hyperintensity on FLAIR imaging and/or bilateral subdural effusion/hematomas in patients with spontaneous intracranial hypotension

    No./Age (y)/SexDiffuse Pachymeningeal Hyperintensity on FLAIR ImagingSubdural Effusion/Hematomas
    1/36/Fbil. OC, falxbil. OC
    2/59/Mbil. OC, falx, tentorium, PFCbil. OC
    3/37/Fbil. OC, falx, tentorium, PFCbil. frontal convexity
    4/37/Fbil. OC, falx, tentorium, PFCbil. frontoparietal convexity
    5/39/Mbil. OC, falx, tentorium, PFCbil. frontal convexity
    6/45/Fbil. OCND
    7/48/Fbil. OC, falx, tentorium, PFCbil. OC
    8/47/Fbil. OC, falxbil. OC*
    • Note:—OC indicates over the supratentorial convexity; PFC, posterior fossa convexity; ND, not detectable; bil., bilateral.

    • * Subdural effusion/hematomas were not found in initial study but were observed in the second study.

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    Table 2:

    Summary of changes in MR imaging appearance in patients with spontaneous intracranial hypotension

    Pt. No.DPMEDPMHFMaximum Thickness of Subdural Effusion/Hematomas
    InitialSecondFollow-UpInitialSecondFollow-UpInitialSecondFollow-Up
    1YesYesSlightlyYesYesNPbil. thickbil. very thickND
    2YesNP†NPYesNP†NDthick/thin*NP†ND
    3YesNPNDYesSlightlyNDbil. thinbil. thinND
    4YesSlightlySlightlyYesNDNDbil. thickbil. very thickbil. thin
    5YesSlightlyNDYesNDNDbil. very thinbil. very thinND
    6YesSlightlyNDYesNDNDND (DPMHF)NDND
    7YesRemainSlightlyYesRemainNDthick/thin*thick/ND (DPMHF)*thin/ND*
    8YesYesSlightlyYesYesNDND (DPMHF)bil. very thinND
    • Note:—DPME indicates diffuse pachymeningeal enhancement; DPMHF, diffuse pachymeningeal hyperintensity on FLAIR imaging; NP, not performed; ND, not detectable; Slightly, slightly remain; bil., bilateral; very thin, ≤3 mm; thin, >3 mm–≤6 mm; thick, >6–≤10 mm; very thick, >10 mm.

    • * Left side/right side.

    • † Only in patient 2, second study was performed after strict bed rest but before successful epidural blood patch.

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American Journal of Neuroradiology
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M. Tosaka, N. Sato, H. Fujimaki, Y. Tanaka, K. Kagoshima, A. Takahashi, N. Saito, Y. Yoshimoto
Diffuse Pachymeningeal Hyperintensity and Subdural Effusion/Hematoma Detected by Fluid-Attenuated Inversion Recovery MR Imaging in Patients with Spontaneous Intracranial Hypotension
American Journal of Neuroradiology Jun 2008, 29 (6) 1164-1170; DOI: 10.3174/ajnr.A1041

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Diffuse Pachymeningeal Hyperintensity and Subdural Effusion/Hematoma Detected by Fluid-Attenuated Inversion Recovery MR Imaging in Patients with Spontaneous Intracranial Hypotension
M. Tosaka, N. Sato, H. Fujimaki, Y. Tanaka, K. Kagoshima, A. Takahashi, N. Saito, Y. Yoshimoto
American Journal of Neuroradiology Jun 2008, 29 (6) 1164-1170; DOI: 10.3174/ajnr.A1041
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