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Theoretic Basis and Technical Implementations of CT Perfusion in Acute Ischemic Stroke, Part 1: Theoretic Basis
A.A. Konstas, G.V. Goldmakher, T.-Y. Lee and M.H. Lev
American Journal of Neuroradiology April 2009, 30 (4) 662-668; DOI: https://doi.org/10.3174/ajnr.A1487
A.A. Konstas
G.V. Goldmakher
T.-Y. Lee

Abstract
SUMMARY: CT perfusion (CTP) is a functional imaging technique that provides important information about capillary-level hemodynamics of the brain parenchyma and is a natural complement to the strengths of unenhanced CT and CT angiography in the evaluation of acute stroke, vasospasm, and other neurovascular disorders. CTP is critical in determining the extent of irreversibly infarcted brain tissue (infarct “core”) and the severely ischemic but potentially salvageable tissue (“penumbra”). This is achieved by generating parametric maps of cerebral blood flow, cerebral blood volume, and mean transit time.
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A.A. Konstas, G.V. Goldmakher, T.-Y. Lee, M.H. Lev
Theoretic Basis and Technical Implementations of CT Perfusion in Acute Ischemic Stroke, Part 1: Theoretic Basis
American Journal of Neuroradiology Apr 2009, 30 (4) 662-668; DOI: 10.3174/ajnr.A1487
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