Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticleBRAIN

Perfusion CT in Patients with Acute Ischemic Stroke Treated with Intra-Arterial Thrombolysis: Predictive Value of Infarct Core Size on Clinical Outcome

R. Gasparotti, M. Grassi, D. Mardighian, M. Frigerio, M. Pavia, R. Liserre, M. Magoni, L. Mascaro, A. Padovani and A. Pezzini
American Journal of Neuroradiology April 2009, 30 (4) 722-727; DOI: https://doi.org/10.3174/ajnr.A1439
R. Gasparotti
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Grassi
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
D. Mardighian
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Frigerio
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Pavia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
R. Liserre
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M. Magoni
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
L. Mascaro
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Padovani
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A. Pezzini
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. ↵
    Thomalla G, Schwark C, Sobesky J, et al. Outcome and symptomatic bleeding complications of intravenous thrombolysis within 6 hours in MRI-selected stroke patients: comparison of a German multicenter study with the pooled data of ATLANTIS, ECASS, and NINDS tPA trials. Stroke 2006;37:852–58. Epub 2006 Jan 26
    Abstract/FREE Full Text
  2. ↵
    Wintermark M, Meuli R, Browaeys P, et al. Comparison of CT perfusion and angiography and MRI in selecting stroke patients for acute treatment. Neurology 2007;68:694–97
    Abstract/FREE Full Text
  3. ↵
    Wardlaw JM, del Zoppo G, Yamaguchi T, et al. Thrombolysis for acute ischaemic stroke. Cochrane Database of Systematic Reviews. 2003 :CD000213. Available at: http://mrw.interscience.wiley.com/cochrane/clsysrev/articles/CD000213/frame.html. Accessed January 9, 2009
  4. ↵
    Wintermark M, Reichhart M, Thiran JP, et al. Prognostic accuracy of cerebral blood flow measurement by perfusion computed tomography, at the time of emergency room admission, in acute stroke patients. Ann Neurol 2002;51:417–32
    CrossRefPubMedWeb of Science
  5. ↵
    Barber PA, Demchuk AM, Zhang J, et al. Validity and reliability of a quantitative computed tomography score in predicting outcome of hyperacute stroke before thrombolytic therapy: ASPECTS Study Group—Alberta Stroke Programme Early CT Score. Lancet 2000;355:1670–74
    CrossRefPubMedWeb of Science
  6. ↵
    Olsen TS, Langhorne P, Diener HC, et al, for the European Stroke Initiative Executive Committee and the EUSI Writing Committee. European Stroke Initiative recommendations for stroke management: update 2003. Cerebrovasc Dis 2003;16:311–37
    CrossRefPubMedWeb of Science
  7. ↵
    Kucinski T, Koch C, Eckert B, et al. Collateral circulation is an independent radiological predictor of outcome after thrombolysis in acute ischaemic stroke. Neuroradiology 2003;45:11–18. Epub 2002 Dec 7
    PubMedWeb of Science
  8. ↵
    Ganz W. The thrombolysis in myocardial infarction (TIMI) trial. N Engl J Med 1985;313:1018
    PubMedWeb of Science
  9. ↵
    Klotz E, Konig M. Perfusion measurements of the brain: using dynamic CT for the quantitative assessment of cerebral ischemia in acute stroke. Eur J Radiol 1999;30:170–84
    PubMed
  10. ↵
    Koenig M, Kraus M, Theek C, et al. Quantitative assessment of the ischemic brain by means of perfusion-related parameters derived from perfusion CT. Stroke 2001;32:431–37
    Abstract/FREE Full Text
  11. ↵
    Schaefer PW, Roccatagliata L, Ledezma C, et al. First-pass quantitative CT perfusion identifies thresholds for salvageable penumbra in acute stroke patients treated with intra-arterial therapy. AJNR Am J Neuroradiol 2006;27:20–25
    Abstract/FREE Full Text
  12. ↵
    Sobesky J, Zaro WO, Lehnhardt FG, et al. Which time-to-peak threshold best identifies penumbral flow? A comparison of perfusion-weighted magnetic resonance imaging and positron emission tomography in acute ischemic stroke. Stroke 2004;35:2843–47
    Abstract/FREE Full Text
  13. ↵
    Muir KW, Halbert HM, Baird TA, et al. Visual evaluation of perfusion computed tomography in acute stroke accurately estimates infarct volume and tissue viability. J Neurol Neurosurg Psychiatry 2006;77:334–39
    Abstract/FREE Full Text
  14. ↵
    Mallows CL. Some comments on Cp. Technometrics 1973;15:661–75
    CrossRefWeb of Science
  15. ↵
    Lev MH, Segal AZ, Farkas J, et al. Utility of perfusion-weighted CT imaging in acute middle cerebral artery stroke treated with intra-arterial thrombolysis: prediction of final infarct volume and clinical outcome. Stroke 2001;32:2021–28
    Abstract/FREE Full Text
  16. ↵
    Parsons MW, Pepper EM, Chan V, et al. Perfusion computed tomography: prediction of final infarct extent and stroke outcome. Ann Neurol 2005;58:672–79
    CrossRefPubMedWeb of Science
  17. ↵
    Arnold M, Schroth G, Nedeltchev K, et al. Intra-arterial thrombolysis in 100 patients with acute stroke due to middle cerebral artery occlusion. Stroke 2002;33:1828–33
    Abstract/FREE Full Text
  18. ↵
    Alexandrov AV, Burgin WS, Demchuk AM, et al. Speed of intracranial clot lysis with intravenous tissue plasminogen activator therapy: sonographic classification and short-term improvement. Circulation 2001;103:2897–902
    Abstract/FREE Full Text
  19. ↵
    Felberg RA, Okon NJ, El-Mitwalli A, et al. Early dramatic recovery during intravenous tissue plasminogen activator infusion: clinical pattern and outcome in acute middle cerebral artery stroke. Stroke 2002;33:1301–07
    Abstract/FREE Full Text
  20. ↵
    Wechsler LR. Does the Merci retriever work? Against. Stroke 2006;37:1341–42, discussion 1342–43. Epub 2006 Apr 6
    FREE Full Text
  21. ↵
    Mayer TE, Hamann GF, Baranczyk J, et al. Dynamic CT perfusion imaging of acute stroke. AJNR Am J Neuroradiol 2000;21:1441–49
    Abstract/FREE Full Text
  22. ↵
    Wintermark M, Flanders AE, Velthuis B, et al. Perfusion-CT assessment of infarct core and penumbra: receiver operating characteristic curve analysis in 130 patients suspected of acute hemispheric stroke. Stroke 2006;37:979–85
    Abstract/FREE Full Text
  23. ↵
    Eastwood JD, Lev MH, Wintermark M, et al. Correlation of early dynamic CT perfusion imaging with whole-brain MR diffusion and perfusion imaging in acute hemispheric stroke. AJNR Am J Neuroradiol 2003;24:1869–75
    Abstract/FREE Full Text
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 30 (4)
American Journal of Neuroradiology
Vol. 30, Issue 4
April 2009
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Perfusion CT in Patients with Acute Ischemic Stroke Treated with Intra-Arterial Thrombolysis: Predictive Value of Infarct Core Size on Clinical Outcome
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
R. Gasparotti, M. Grassi, D. Mardighian, M. Frigerio, M. Pavia, R. Liserre, M. Magoni, L. Mascaro, A. Padovani, A. Pezzini
Perfusion CT in Patients with Acute Ischemic Stroke Treated with Intra-Arterial Thrombolysis: Predictive Value of Infarct Core Size on Clinical Outcome
American Journal of Neuroradiology Apr 2009, 30 (4) 722-727; DOI: 10.3174/ajnr.A1439

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Perfusion CT in Patients with Acute Ischemic Stroke Treated with Intra-Arterial Thrombolysis: Predictive Value of Infarct Core Size on Clinical Outcome
R. Gasparotti, M. Grassi, D. Mardighian, M. Frigerio, M. Pavia, R. Liserre, M. Magoni, L. Mascaro, A. Padovani, A. Pezzini
American Journal of Neuroradiology Apr 2009, 30 (4) 722-727; DOI: 10.3174/ajnr.A1439
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Assessment of computed tomography perfusion software in predicting spatial location and volume of infarct in acute ischemic stroke patients: a comparison of Sphere, Vitrea, and RAPID
  • Assessment of a Bayesian Vitrea CT Perfusion Analysis to Predict Final Infarct and Penumbra Volumes in Patients with Acute Ischemic Stroke: A Comparison with RAPID
  • The POST trial: initial post-market experience of the Penumbra system: revascularization of large vessel occlusion in acute ischemic stroke in the United States and Europe
  • Predictive Value of RAPID Assessed Perfusion Thresholds on Final Infarct Volume in SWIFT PRIME (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment)
  • Interaction of Recanalization, Intracerebral Hemorrhage, and Cerebral Edema After Intravenous Thrombolysis
  • Effect of Collaterals on Clinical Presentation, Baseline Imaging, Complications, and Outcome in Acute Stroke
  • Value of Computed Tomographic Perfusion-Based Patient Selection for Intra-Arterial Acute Ischemic Stroke Treatment
  • Computed Tomographic Angiography and Cerebral Blood Volume Can Predict Final Infarct Volume and Outcome After Recanalization
  • Relative Cerebral Blood Volume as a Marker of Durable Tissue-at-Risk Viability in Hyperacute Ischemic Stroke
  • Implementation of a patient selection protocol for intra-arterial therapy increases treatment rates in patients with acute ischemic stroke
  • Prediction of Recanalization Trumps Prediction of Tissue Fate: The Penumbra: A Dual-edged Sword
  • Pre-intervention triage incorporating perfusion imaging improves outcomes in patients undergoing endovascular stroke therapy: a comparison with the device trials
  • Location of the Clot and Outcome of Perfusion Defects in Acute Anterior Circulation Stroke Treated with Intravenous Thrombolysis
  • Multiparametric MRI and CT Models of Infarct Core and Favorable Penumbral Imaging Patterns in Acute Ischemic Stroke
  • Leukoaraiosis and Sex Predict the Hyperacute Ischemic Core Volume
  • Selecting stroke patients for intra-arterial therapy
  • Systematic Review of Methods for Assessing Leptomeningeal Collateral Flow
  • The POST trial: initial post-market experience of the Penumbra system: revascularization of large vessel occlusion in acute ischemic stroke in the United States and Europe
  • Cost-effectiveness of multimodal CT for evaluating acute stroke
  • Imaging in acute ischaemic stroke: essential for modern stroke care
  • Crossref (74)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Systematic Review of Methods for Assessing Leptomeningeal Collateral Flow
    F. McVerry, D.S. Liebeskind, K.W. Muir
    American Journal of Neuroradiology 2012 33 3
  • The POST trial: initial post-market experience of the Penumbra system: revascularization of large vessel occlusion in acute ischemic stroke in the United States and Europe
    Robert Tarr, Dan Hsu, Zsolt Kulcsar, Christophe Bonvin, Daniel Rufenacht, Karsten Alfke, Robert Stingele, Olav Jansen, Donald Frei, Richard Bellon, Michael Madison, Tobias Struffert, Arnd Dorfler, Iris Q Grunwald, Wolfgang Reith, Anton Haass
    Journal of NeuroInterventional Surgery 2010 2 4
  • Predictive Value of RAPID Assessed Perfusion Thresholds on Final Infarct Volume in SWIFT PRIME (Solitaire With the Intention for Thrombectomy as Primary Endovascular Treatment)
    Maxim Mokin, Elad I. Levy, Jeffrey L. Saver, Adnan H. Siddiqui, Mayank Goyal, Alain Bonafé, Christophe Cognard, Reza Jahan, Gregory W. Albers
    Stroke 2017 48 4
  • Value of Computed Tomographic Perfusion–Based Patient Selection for Intra-Arterial Acute Ischemic Stroke Treatment
    Jordi Borst, Olvert A. Berkhemer, Yvo B.W.E.M. Roos, Ed van Bavel, Wim H. van Zwam, Robert J. van Oostenbrugge, Marianne A.A. van Walderveen, Hester F. Lingsma, Aad van der Lugt, Diederik W.J. Dippel, Albert J. Yoo, Henk A. Marquering, Charles B.L.M. Majoie, Puck S.S. Fransen, Debbie Beumer, Lucie A. van den Berg, Wouter J. Schonewille, Jan Albert Vos, Paul J. Nederkoorn, Marieke J.H. Wermer, Julie Staals, Jeannette Hofmeijer, Jacques A. van Oostayen, Geert J. Lycklama à Nijeholt, Jelis Boiten, Patrick A. Brouwer, Bart J. Emmer, Sebastiaan F. de Bruijn, Lukas C. van Dijk, L. Jaap Kappelle, Rob H. Lo, Ewoud J. van Dijk, Joost de Vries, Paul L.M. de Kort, Jan S.P. van den Berg, Boudewijn A.A.M. van Hasselt, Leo A.M. Aerden, René J. Dallinga, Marieke C. Visser, Joseph C.J. Bot, Patrick C. Vroomen, Omid Eshghi, Tobien H.C.M.L. Schreuder, Roel J.J. Heijboer, Koos Keizer, Alexander V. Tielbeek, Heleen M. den Hertog, Dick G. Gerrits, Renske M. van den Berg-Vos, Giorgos B. Karas, Ewout W. Steyerberg, H. Zwenneke Flach, Marieke E.S. Sprengers, Sjoerd F.M. Jenniskens, Ludo F.M. Beenen, René van den Berg, Peter J. Koudstaal, Martin M. Brown, Thomas Liebig, Theo Stijnen, Tommy Andersson, Heinrich Mattle, Nils Wahlgren, Esther van der Heijden, Naziha Ghannouti, Nadine Fleitour, Imke Hooijenga, Corina Puppels, Wilma Pellikaan, Annet Geerling, Annemieke Lindl-Velema, Gina van Vemde, Ans de Ridder, Paut Greebe, José de Bont-Stikkelbroeck, Joke de Meris, Kirsten Janssen, Willy Struijk, Tiny Simons, Gert Messchendorp, Friedus van der Minne, Hester Bongenaar, Silvan Licher, Nikki Boodt, Adriaan Ros, Esmee Venema, Ilse Slokkers, Raymie-Jayce Ganpat, Maxim Mulder, Nawid Saiedie, Alis Heshmatollah, Stefanie Schipperen, Stefan Vinken, Tiemen van Boxtel, Jeroen Koets, Merel Boers, Emilie Santos, Ivo Jansen, Manon Kappelhof, Marit Lucas, Ralph Geuskens, Renan Sales Barros, Roeland Dobbe, Marloes Csizmadia
    Stroke 2015 46 12
  • Effect of Collaterals on Clinical Presentation, Baseline Imaging, Complications, and Outcome in Acute Stroke
    E.M. Fanou, J. Knight, R.I. Aviv, S.-P. Hojjat, S.P. Symons, L. Zhang, M. Wintermark
    American Journal of Neuroradiology 2015 36 12
  • Precision Stroke Animal Models: the Permanent MCAO Model Should Be the Primary Model, Not Transient MCAO
    Devin W. McBride, John H. Zhang
    Translational Stroke Research 2017 8 5
  • Multiparametric MRI and CT Models of Infarct Core and Favorable Penumbral Imaging Patterns in Acute Ischemic Stroke
    Chelsea S. Kidwell, Max Wintermark, Deidre A. De Silva, Timothy J. Schaewe, Reza Jahan, Sidney Starkman, Tudor Jovin, Jason Hom, Mouhammad Jumaa, Jeffrie Schreier, Jeffrey Gornbein, David S. Liebeskind, Jeffry R. Alger, Jeffrey L. Saver
    Stroke 2013 44 1
  • Acute cardioembolic stroke: an update
    Adrià Arboix, Josefina Alió
    Expert Review of Cardiovascular Therapy 2011 9 3
  • CT Perfusion Imaging in Acute Stroke
    Angelos A. Konstas, Max Wintermark, Michael H. Lev
    Neuroimaging Clinics of North America 2011 21 2
  • Leukoaraiosis and Sex Predict the Hyperacute Ischemic Core Volume
    Nils Henninger, Eugene Lin, Diogo C. Haussen, Laura L. Lehman, Deepak Takhtani, Magdy Selim, Majaz Moonis
    Stroke 2013 44 1

More in this TOC Section

  • Fast Contrast-Enhanced 4D MRA and 4D Flow MRI Using Constrained Reconstruction (HYPRFlow): Potential Applications for Brain Arteriovenous Malformations
  • Quiet PROPELLER MRI Techniques Match the Quality of Conventional PROPELLER Brain Imaging Techniques
  • Predictors of Reperfusion in Patients with Acute Ischemic Stroke
Show more Brain

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire