Article Figures & Data
Figures
- Fig 1.
Depictions of regions of interest used in this study. A, T2-weighted trace image. B and C, T2-weighted images. A, Regions of interest are drawn in the head of the caudate nucleus (regions of interest 1 and 2), the putamen (regions of interest 3 and 4), and the globus pallidus (regions of interest 5 and 6). B, Regions of interest are drawn in the prefrontal white matter (regions of interest 1 and 2), the genu (region of interest 3), and the splenium (region of interest 4) of the corpus callosum. C, Regions of interest are drawn in regions of the poster limb of the internal capsule (regions of interest 1 and 2).
- Fig 2.
The scatterplots of FA (A) and eigenvalues λ23 (B) and λ1 (C) with aging in the putamen (λ1, λ23: × 10−4 mm2/s).
- Fig 3.
The color-coded FA (A), λ1 (B), λ2 (C), and λ3 (D) maps at the level of the basal ganglia (λ1, λ2, λ3: × 10−4 mm2/s).
Tables
Mean values and Pearson correlations between age and DTI metrics in the basal ganglia (MD, λ1, λ23 × 10−4 mm2/s)
Region MD (Mean ± SD) FA (Mean ± SD) λ1 (Mean ± SD) λ23 (Mean ± SD) Caudate 6.88 ± 0.42, r = −0.319, P = .007 0.24 ± 0.03, r = 0.178, P = .138 8.57 ± 0.46, r = −0.299, P = .011 6.03 ± 0.43, r = −0.312, P = .008 Putamen 6.45 ± 0.36, r = −0.410, P < .001 0.23 ± 0.04, r = 0.535, P < .001 7.93 ± 0.27, r = −0.200, P = .094 5.71 ± 0.43, r = −0.451, P < .001 Globus pallidus 6.00 ± 0.49, r = −0.142, P = .238 0.36 ± 0.04, r = 0.276, P = .020 8.16 ± 0.42, r = −0.117, P = .329 4.89 ± 0.45, r = −0.215, P = .072 Prefrontal 7.18 ± 0.51, r = 0.314, P = .008 0.35 ± 0.05, r = −0.391, P = .001 9.82 ± 0.65, r = 0.053, P = .663 5.86 ± 0.56, r = 0.403, P < .001 Genu 6.98 ± 0.65, r = 0.319, P = .007 0.65 ± 0.06, r = −0.307, P = .009 12.97 ± 1.19, r = 0.139, P = .249 3.98 ± 0.65, r = 0.353, P = .003 Splenium 6.77 ± 0.67, r = −0.153, P = .202 0.75 ± 0.05, r = −0.008, P = .946 14.16 ± 1.51, r = −0.156, P = .194 3.06 ± 0.56, r = −0.066, P = .585 Internal capsule 6.43 ± 0.51, r = −0.185, P = .123 0.69 ± 0.04, r = 0.013, P = .914 12.56 ± 0.85, r = −0.231, P = .053 3.36 ± 0.46, r = −0.090, P = .458
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