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Control (n = 21) PED (n = 21) P Value Age (mean) (yr) 58.3 ± 18.6 51.0 ± 12.8 .15 Female 19 (90.5%) 18 (85.7%) .63 Hypertension 13 (61.9%) 9 (42.9%) .22 Diabetes mellitus 1 (4.8%) 1 (4.8%) 1.00 Previous SAH 0 2 (9.5%) .15 Family history of intracranial aneurysm 2 (9.5%) 1 (4.8%) .55 Tobacco .11 Current 2 (9.5%) 7 (33.3%) Prior (<1 yr) 4 (19.1%) 5 (23.8%) No 15 (71.4%) 9 (42.9%) Control (n = 22) PED (n = 22) Total P Value Dome size Mean (mm) (13.9 ± 6.7) (14.9 ± 6.3) .52 Range (mm) 4–30 6–26 Median (mm) 13 14.5 Small 7 (31.8%) 7 (31.8%) 14 (31.8%) Large 12 (54.5%) 12 (54.5%) 24 (54.5%) Giant 3 (13.6%) 3 (13.6%) 6 (13.6%) Location Carotido-ophthalmic 12 (54.5%) 12 (54.5%) 24 (54.5%) Cavernous 9 (40.9%) 9 (40.9% 18 (40.9%) Hypophyseal 1 (4.5%) 1 (4.5%) 2 (4.5%) Control PED Only coils 14 (63.6%) 0 Balloon-assisted 7 (31.8%) 0 Stent-assisted 2 (9.1%) 0 Iatrogenic occlusion 8 (36.4%) 0 Complications Control (n = 4) PED (n= 3) P Value Periprocedural technical 1.00 Perforation 1 (4.5%) 0 Coil-prolapsing flow-limiting 1 (4.5%) 0 Thrombus formation 2 (9.1%)a 1 (4.5%) Catheter-induced vasospasm 0 1 (4.5%) In-stent stenosis (balloon use) 0 1 (4.5%) 1.00 Early clinical (No.) 3 2 GI bleed 0 1 (4.5%) Hemodynamic instability 1 (4.5%) 0 Transient right weakness (no stroke) 1 (4.5%) 0 Groin hematoma 0 1 (4.5%) Transient worsening of ophthalmoparesis 0 1 (4.5%) Retroperitoneal hematoma 1 (4.5%) 0 -
Note:—GI indicates gastrointestinal.
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↵a Intraoperative thrombolytic use.
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Control PED Odds Ratio (95% CI) P Value Class 1 10 (45.4%) 17 (77.3%) 4.1 (1.1–15.1) .03 Class 2 7 (31.8%) 3 (13.6%) .22 Class 3 5 (22.7%) 2 (9.1%) .15 -
Note:—CI indicates confidence interval.
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Control (14 Aneurysms) PED (21 Aneurysms) Odds Ratio (95% CI) P Value Class 1 3 (21.4%) 16 (76.2%) 11.7 (2.3–5) .0014 Class 2 7 (50.0%) 3 (14.3%) 0.2 (0.03–0.83) .02 Class 3 4 (28.6%) 2 (9.5%) .14 -
Note:—CI indicates confidence interval.
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↵a After excluding the 8 patients treated with parent artery sacrifice in the control group and the patient found to have an asymptomatic ICA occlusion in the PED group.
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