Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePatient Safety
Open Access

Point-of-Care Testing for Anticoagulation Monitoring in Neuroendovascular Procedures

H.M. Hussein, A.L. Georgiadis and A.I. Qureshi
American Journal of Neuroradiology August 2012, 33 (7) 1211-1220; DOI: https://doi.org/10.3174/ajnr.A2621
H.M. Hussein
aFrom Zeenat Qureshi Stroke Research Center, University of Minnesota, Minneapolis, Minnesota.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A.L. Georgiadis
aFrom Zeenat Qureshi Stroke Research Center, University of Minnesota, Minneapolis, Minnesota.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
A.I. Qureshi
aFrom Zeenat Qureshi Stroke Research Center, University of Minnesota, Minneapolis, Minnesota.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Riedel CH,
    2. Tietke M,
    3. Alfke K,
    4. et al
    . Subacute stent thrombosis in intracranial stenting. Stroke 2009;40:1310–14
    Abstract/FREE Full Text
  2. 2.↵
    1. Ries T,
    2. Buhk JH,
    3. Kucinski T,
    4. et al
    . Intravenous administration of acetylsalicylic acid during endovascular treatment of cerebral aneurysms reduces the rate of thromboembolic events. Stroke 2006;37:1816–21
    Abstract/FREE Full Text
  3. 3.↵
    1. Qureshi AI,
    2. Luft AR,
    3. Sharma M,
    4. et al
    . Prevention and treatment of thromboembolic and ischemic complications associated with endovascular procedures. Part II. Clinical aspects and recommendations. Neurosurgery 2000;46:1360–75, discussion 75–76
    CrossRefPubMedWeb of Science
  4. 4.↵
    1. Krpski WC,
    2. Bass A,
    3. Kelly AB,
    4. et al
    . Heparin-resistant thrombus formation by endovascular stents in baboons: interruption by a synthetic antithrombin. Circulation 1990;82:570–77
    Abstract/FREE Full Text
  5. 5.↵
    1. Chaer RA,
    2. Graham JA,
    3. Mureebe L
    . Platelet function and pharmacologic inhibition. Vasc Endovascular Surg 2006;40:261–67
    Abstract/FREE Full Text
  6. 6.↵
    1. Hirsh J,
    2. Bauer KA,
    3. Donati MB,
    4. et al
    . Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008;133(6 suppl):141S–59S
    CrossRefPubMedWeb of Science
  7. 7.↵
    1. Laux V,
    2. Perzborn E,
    3. Heitmeier S,
    4. et al
    . Direct inhibitors of coagulation proteins: the end of the heparin and low-molecular-weight heparin era for anticoagulant therapy? Thromb Haemost 2009;102:892–99
    PubMedWeb of Science
  8. 8.↵
    1. SoRelle R
    . 1999 Bristol-Myers Squibb cardiovascular metabolic research award: Earl Davie, PhD, defined the system of blood coagulation. Circulation 1999;100:332
    FREE Full Text
  9. 9.↵
    1. Montalescot G,
    2. White HD,
    3. Gallo R,
    4. et al
    . Enoxaparin versus unfractionated heparin in elective percutaneous coronary intervention. N Engl J Med 2006;355:1006–17
    CrossRefPubMedWeb of Science
  10. 10.↵
    1. El Rouby S,
    2. Cohen M,
    3. Gonzales A,
    4. et al
    . The use of a HEMOCHRON JR. HEMONOX point of care test in monitoring the anticoagulant effects of enoxaparin during interventional coronary procedures. J Thromb Thrombolysis 2006;21:137–45
    CrossRefPubMedWeb of Science
  11. 11.↵
    1. Saw J,
    2. Kereiakes DJ,
    3. Mahaffey KW,
    4. et al
    . Evaluation of a novel point-of-care enoxaparin monitor with central laboratory anti-Xa levels. Thromb Res 2003;112:301–06
    CrossRefPubMedWeb of Science
  12. 12.↵
    1. Toschi V,
    2. Lettino M,
    3. Gallo R,
    4. et al
    . Biochemistry and biology of hirudin. Coron Artery Dis 1996;7:420–28
    CrossRefPubMedWeb of Science
  13. 13.↵
    1. Warkentin TE,
    2. Greinacher A,
    3. Koster A
    . Bivalirudin. Thromb Haemost 2008, 99:830–39
    PubMedWeb of Science
  14. 14.↵
    1. Witting JI,
    2. Bourdon P,
    3. Maraganore JM,
    4. et al
    . Hirulog-1 and -B2 thrombin specificity. Biochem J 1992;287(pt 2):663–64
    FREE Full Text
  15. 15.↵
    1. Bittl JA,
    2. Chaitman BR,
    3. Feit F,
    4. et al
    . Bivalirudin versus heparin during coronary angioplasty for unstable or postinfarction angina: final report reanalysis of the Bivalirudin Angioplasty Study. Am Heart J 2001;142:952–59
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Lincoff AM,
    2. Kleiman NS,
    3. Kottke-Marchant K,
    4. et al
    . Bivalirudin with planned or provisional abciximab versus low-dose heparin and abciximab during percutaneous coronary revascularization: results of the Comparison of Abciximab Complications with Hirulog for Ischemic Events Trial (CACHET). Am Heart J 2002;143:847–53
    CrossRefPubMedWeb of Science
  17. 17.↵
    1. Lincoff AM,
    2. Bittl JA,
    3. Harrington RA,
    4. et al
    . Bivalirudin and provisional glycoprotein IIb/IIIa blockade compared with heparin and planned glycoprotein IIb/IIIa blockade during percutaneous coronary intervention: REPLACE-2 randomized trial. JAMA 2003;289:853–63
    CrossRefPubMedWeb of Science
  18. 18.↵
    1. Stone GW,
    2. McLaurin BT,
    3. Cox DA,
    4. et al
    . Bivalirudin for patients with acute coronary syndromes. N Engl J Med 2006;355:2203–16
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Stone GW,
    2. Witzenbichler B,
    3. Guagliumi G,
    4. et al
    . Bivalirudin during primary PCI in acute myocardial infarction. N Engl J Med 2008;358:2218–30
    CrossRefPubMedWeb of Science
  20. 20.↵
    1. Swan SK,
    2. Hursting MJ
    . The pharmacokinetics and pharmacodynamics of argatroban: effects of age, gender, and hepatic or renal dysfunction. Pharmacotherapy 2000;20:318–29
    CrossRefPubMedWeb of Science
  21. 21.↵
    1. Chia S,
    2. Van Cott EM,
    3. Raffel OC,
    4. et al
    . Comparison of activated clotting times obtained using Hemochron and Medtronic analysers in patients receiving anti-thrombin therapy during cardiac catheterisation. Thromb Haemost 2009;101:535–40
    PubMed
  22. 22.↵
    1. van Putten J,
    2. van de Ruit M,
    3. Beunis M,
    4. et al
    . Automated determination of heparin with chromogenic substrates. Haemostasis 1984;14:184–94
    PubMed
  23. 23.↵
    1. Tietz NW
    , ed. Clinical guide to laboratory tests. Philadelphia: W. B. Saunders Company; 1995:228–29
  24. 24.↵
    1. Hattersley PG
    . Activated coagulation time of whole blood. JAMA 1966;196:436–40
    CrossRefPubMedWeb of Science
  25. 25.↵
    1. Van Cott EM
    . Point-of-care testing in coagulation. Clin Lab Med 2009;29:543–53
    CrossRefPubMed
  26. 26.↵
    1. Feindt P,
    2. Seyfert UT,
    3. Volkmer I,
    4. et al
    . Celite and kaolin produce differing activated clotting times during cardiopulmonary bypass under aprotinin therapy. Thorac Cardiovasc Surg 1994;42:218–21
    PubMedWeb of Science
  27. 27.↵
    1. Andrew M,
    2. MacIntyre B,
    3. MacMillan J,
    4. et al
    . Heparin therapy during cardiopulmonary bypass in children requires ongoing quality control. Thromb Haemost 1993;70:937–41
    PubMedWeb of Science
  28. 28.↵
    1. Marmur JD,
    2. Bullock-Palmer RP,
    3. Poludasu S,
    4. et al
    . Avoiding intelligence failures in the cardiac catheterization laboratory: strategies for the safe and rational use of dalteparin or enoxaparin during percutaneous coronary intervention. J Invasive Cardiol 2009;21:653–64
    PubMed
  29. 29.↵
    1. Lawrence M,
    2. Mixon TA,
    3. Cross D,
    4. et al
    . Assessment of anticoagulation using activated clotting times in patients receiving intravenous enoxaparin during percutaneous coronary intervention. Catheter Cardiovasc Interv 2004;61:52–55
    CrossRefPubMedWeb of Science
  30. 30.↵
    1. Marmur JD,
    2. Anand SX,
    3. Bagga RS,
    4. et al
    . The activated clotting time can be used to monitor the low molecular weight heparin dalteparin after intravenous administration. J Am Col Cardiol 2003;41:394–402
    CrossRefPubMedWeb of Science
  31. 31.↵
    1. Dougherty KG,
    2. Gaos CM,
    3. Bush HS,
    4. et al
    . Activated clotting times and activated partial thromboplastin times in patients undergoing coronary angioplasty who receive bolus doses of heparin. Cathet Cardiovasc Diagn 1992;26:260–63
    PubMedWeb of Science
  32. 32.↵
    1. Zahn R,
    2. Haubelt H,
    3. Bechtloff S,
    4. et al
    . Laboratory monitoring of heparin and the combination of heparin and the platelet glycoprotein IIb/IIIa receptor antibody fragment abciximab (c7E3) in patients undergoing percutaneous transluminal coronary angioplasty (PTCA). Herz 2003;28:445–52
    CrossRefPubMed
  33. 33.↵
    American Association for Clinical Chemistry. Laboratory Medicine Practice Guidelines. 2007: www.aacc.org/members/nacb/LMPG/OnlineGuide/PublishedGuidelines/poct/Pages/poctpdf.aspx. Accessed December 2010
  34. 34.↵
    1. Shimada YJ,
    2. Nakra NC,
    3. Fox JT,
    4. et al
    . Relation of race (Asian, African-American, European-American, and Hispanic) to activated clotting time after weight-adjusted bolus of heparin during percutaneous coronary intervention. Am J Cardiol 2010;105:629–32
    CrossRefPubMed
  35. 35.↵
    1. Pesola GR,
    2. Johnson A,
    3. Pesola DA
    . Percutaneous transluminal coronary angioplasty: comparison of arterial vs. venous activated clotting time. Cathet Cardiovasc Diagn 1996;37:140–44
    CrossRefPubMedWeb of Science
  36. 36.↵
    1. Spinler SA,
    2. Wittkowsky AK,
    3. Nutescu EA,
    4. et al
    . Anticoagulation monitoring. Part 2. Unfractionated heparin and low-molecular-weight heparin. Ann Pharmacother 2005;39:1275–85
    CrossRefPubMedWeb of Science
  37. 37.↵
    Proceedings of the seventh ACCP conference on antithrombotic and thrombolytic therapy: Evidence-based guidelines. Chest 2004;126:172S–696S
    CrossRefPubMedWeb of Science
  38. 38.↵
    1. Ferguson JJ,
    2. Dougherty KG,
    3. Gaos CM,
    4. et al
    . Relation between procedural activated coagulation time and outcome after percutaneous transluminal coronary angioplasty. J Am Coll Cardiol 1994;23:1061–65
    PubMedWeb of Science
  39. 39.↵
    1. Narins CR,
    2. Hillegass WB Jr.,
    3. Nelson CL,
    4. et al
    . Relation between activated clotting time during angioplasty and abrupt closure. Circulation 1996;93:667–71
    Abstract/FREE Full Text
  40. 40.↵
    1. Pinto DS,
    2. Lorenz DP,
    3. Murphy SA,
    4. et al
    . Association of an activated clotting time < or =250 seconds with adverse event rates after percutaneous coronary intervention using tirofiban and heparin (a TAC TICS-TIMI 18 substudy). Am J Cardiol 2003;91:976–78, A4
    CrossRefPubMedWeb of Science
  41. 41.↵
    1. Montalescot G,
    2. Cohen M,
    3. Salette G,
    4. et al
    . Impact of anticoagulation levels on outcomes in patients undergoing elective percutaneous coronary intervention: insights from the STEEPLE trial. Eur Heart J 2008;29:462–71
    Abstract/FREE Full Text
  42. 42.↵
    1. Chew DP,
    2. Bhatt DL,
    3. Lincoff AM,
    4. et al
    . Defining the optimal activated clotting time during percutaneous coronary intervention: aggregate results from 6 randomized, controlled trials. Circulation 2001;103:961–66
    Abstract/FREE Full Text
  43. 43.↵
    1. Brener SJ,
    2. Bhatt DL,
    3. Moliterno DJ,
    4. et al
    . Revisiting optimal anticoagulation with unfractionated heparin during coronary stent implantation. Am J Cardiol 2003;92:1468–71
    CrossRefPubMedWeb of Science
  44. 44.↵
    1. Bertrand OF,
    2. Rodes-Cabau J,
    3. Rinfret S,
    4. et al
    . Impact of final activated clotting time after transradial coronary stenting with maximal antiplatelet therapy. Am J Cardiol 2009;104:1235–40
    CrossRefPubMedWeb of Science
  45. 45.↵
    1. Schumacher HC,
    2. Meyers PM,
    3. Higashida RT,
    4. et al
    . Reporting standards for angioplasty and stent-assisted angioplasty for intracranial atherosclerosis. Stroke 2009;40:e348–65
    Abstract/FREE Full Text
  46. 46.↵
    1. Jiang WJ,
    2. Wang YJ,
    3. Du B,
    4. et al
    . Stenting of symptomatic M1 stenosis of middle cerebral artery: an initial experience of 40 patients. Stroke 2004;35:1375–80
    Abstract/FREE Full Text
  47. 47.↵
    1. Henkes H,
    2. Miloslavski E,
    3. Lowens S,
    4. et al
    . Treatment of intracranial atherosclerotic stenoses with balloon dilatation and self-expanding stent deployment (WingSpan). Neuroradiology 2005;47:222–28
    CrossRefPubMedWeb of Science
  48. 48.↵
    1. Lylyk P,
    2. Cohen JE,
    3. Ceratto R,
    4. et al
    . Angioplasty and stent placement in intracranial atherosclerotic stenoses and dissections. AJNR Am J Neuroradiol 2002;23:430–36
    Abstract/FREE Full Text
  49. 49.↵
    1. Levy EI,
    2. Boulos AS,
    3. Guterman LR
    . Stent-assisted endoluminal revascularization for the treatment of intracranial atherosclerotic disease. Neurol Res 2002;24:337–46
    CrossRefPubMedWeb of Science
  50. 50.↵
    1. Castellan L,
    2. Causin F,
    3. Danieli D,
    4. et al
    . Carotid stenting with filter protection: correlation of ACT values with angiographic and histopathologic findings. J Neuroradiol 2003;30:103–08
    PubMedWeb of Science
  51. 51.↵
    1. Yokote H,
    2. Terada T,
    3. Ryujin K,
    4. et al
    . Percutaneous transluminal angioplasty for intracranial arteriosclerotic lesions. Neuroradiology 1998;40:590–96
    CrossRefPubMedWeb of Science
  52. 52.↵
    1. Qureshi AI,
    2. Suri MF,
    3. Siddiqui AM,
    4. et al
    . Clinical and angiographic results of dilatation procedures for symptomatic intracranial atherosclerotic disease. J Neuroimaging 2005;15:240–49
    CrossRefPubMedWeb of Science
  53. 53.↵
    1. Gress DR,
    2. Smith WS,
    3. Dowd CF,
    4. et al
    . Angioplasty for intracranial symptomatic vertebrobasilar ischemia. Neurosurgery 2002;51:23–27, discussion 27–29
    CrossRefPubMedWeb of Science
  54. 54.↵
    1. Saw J,
    2. Bajzer C,
    3. Casserly IP,
    4. et al
    . Evaluating the optimal activated clotting time during carotid artery stenting. Am J Cardiol 2006;97:1657–60
    CrossRefPubMed
  55. 55.↵
    1. Yadav JS,
    2. Wholey MH,
    3. Kuntz RE,
    4. et al
    . Protected carotid-artery stenting versus endarterectomy in high-risk patients. N Engl J Med 2004;351:1493–501
    CrossRefPubMedWeb of Science
  56. 56.↵
    1. Brott TG,
    2. Hobson RW 2nd.,
    3. Howard G,
    4. et al
    . Stenting versus endarterectomy for treatment of carotid-artery stenosis. N Engl J Med 2010;363:11–23. Epub 2010 May 26
    CrossRefPubMedWeb of Science
  57. 57.↵
    1. Cavusoglu E,
    2. Lakhani M,
    3. Marmur JD
    . The activated clotting time (ACT) can be used to monitor enoxaparin and dalteparin after intravenous administration. J Invasive Cardiol 2005;17:416–21
    PubMed
  58. 58.↵
    1. Marmur JD,
    2. Lakhani M,
    3. El Rouby S,
    4. et al
    . A novel point-of-care assay for the monitoring of low-molecular weight heparins in the cardiac catheterization laboratory. J Invasive Cardiol 2008;20:449–54
    PubMedWeb of Science
  59. 59.↵
    1. Silvain J,
    2. Beygui F,
    3. Ankri A,
    4. et al
    . Enoxaparin anticoagulation monitoring in the catheterization laboratory using a new bedside test. J Am Coll Cardiol 2010;55:617–25
    CrossRefPubMedWeb of Science
  60. 60.↵
    1. Casserly IP,
    2. Topol EJ,
    3. Jia G,
    4. et al
    . Effect of abciximab versus tirofiban on activated clotting time during percutaneous intervention and its relation to clinical outcomes: observations from the TARGET trial. Am J Cardiol 2003;92:125–29
    PubMed
  61. 61.↵
    1. Moliterno DJ,
    2. Califf RM,
    3. Aguirre FV,
    4. et al
    . Effect of platelet glycoprotein IIb/IIIa integrin blockade on activated clotting time during percutaneous transluminal coronary angioplasty or directional atherectomy (the EPIC trial): evaluation of c7E3 Fab in the Prevention of Ischemic Complications trial. Am J Cardiol 1995;75:559–62
    CrossRefPubMedWeb of Science
  62. 62.↵
    1. Ammar T,
    2. Scudder LE,
    3. Coller BS
    . In vitro effects of the platelet glycoprotein IIb/IIIa receptor antagonist c7E3 Fab on the activated clotting time. Circulation 1997;95:614–17
    Abstract/FREE Full Text
  63. 63.↵
    1. Dauerman HL,
    2. Ball SA,
    3. Goldberg RJ,
    4. et al
    . Activated clotting times in the setting of eptifibatide use during percutaneous coronary intervention. J Thromb Thrombolysis. 2002;13:127–32
    CrossRefPubMed
  64. 64.↵
    1. Furman MI,
    2. Krueger LA,
    3. Frelinger AL 3rd.,
    4. et al
    . GPIIb-IIIa antagonist-induced reduction in platelet surface factor V/Va binding and phosphatidylserine expression in whole blood. Thromb Haemost 2000;84:492–98
    PubMed
  65. 65.↵
    1. Smith SC Jr.,
    2. Feldman TE,
    3. Hirshfeld JW Jr.,
    4. et al
    . ACC/AHA/SCAI 2005 guideline update for percutaneous coronary intervention: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/SCAI Writing Committee to Update 2001 Guidelines for Percutaneous Coronary Intervention). Circulation 2006;113:e166–286
    FREE Full Text
  66. 66.↵
    1. Tolleson TR,
    2. O'Shea JC,
    3. Bittl JA,
    4. et al
    . Relationship between heparin anticoagulation and clinical outcomes in coronary stent intervention: observations from the ESPRIT trial. J Am Coll Cardiol 2003;41:386–93
    CrossRefPubMedWeb of Science
  67. 67.↵
    Hemochron [package insert]. http://www.itcmed.com/Products 2010
  68. 68.↵
    1. Pan C-M,
    2. Jobes D,
    3. Van Riper D,
    4. et al
    . A modified microsample ACT test for heparin monitoring. J Extra Corpor Technol 1996;28:16–20
  69. 69.↵
    1. Despotis GJ,
    2. Joist JH,
    3. Hogue CW Jr.,
    4. et al
    . The impact of heparin concentration and activated clotting time monitoring on blood conservation: a prospective, randomized evaluation in patients undergoing cardiac operation. J Thorac Cardiovasc Surg 1995;110:46–54
    CrossRefPubMedWeb of Science
  70. 70.↵
    1. Jaryno SA,
    2. Zucker ML,
    3. LaDuca FM
    . The Hemochron Response RxDx heparin and protamine dosing system. J Extra Corpor Technol 2004;36:258–62
    PubMed
  71. 71.↵
    1. Shore-Lesserson L,
    2. Reich DL,
    3. DePerio M
    . Heparin and protamine titration do not improve haemostasis in cardiac surgical patients. Can J Anaesth 1998;45:10–18
    PubMedWeb of Science
  72. 72.↵
    1. Silvain J,
    2. Beygui F,
    3. Ankri A,
    4. et al
    . Enoxaparin anticoagulation monitoring in the catheterization laboratory using a new bedside test. J Am Coll Cardiol 2010;55:617–25
    CrossRefPubMedWeb of Science
  73. 73.↵
    Medtronic; Minneapolis, Minnesota. http://www.medtronic.com/for-healthcare-professionals/products-therapies/cardiovascular/therapies/perfusion/index.htm#tab2. Accessed December 2010
  74. 74.↵
    1. Despotis GJ,
    2. Alsoufiev AL,
    3. Spitznagel E,
    4. et al
    . Response of kaolin act to haparin: Evaluation with an automated assay and higher heparin doses. Annal Thoracic Surg 1996;61:795–99
    CrossRef
  75. 75.↵
    1. Despotis GJ,
    2. Summerfield AL,
    3. Joist JH,
    4. et al
    . Comparison of activated coagulation time and whole blood heparin measurements with laboratory plasma anti-xa heparin concentration in patients having cardiac operations. J Thoracic Cardiovasc Surg 1994;108:1076–82
    PubMedWeb of Science
  76. 76.↵
    1. Garvin S,
    2. Fitzgerald DC,
    3. Despotis G,
    4. et al
    . Heparin concentration-based anticoagulation for cardiac surgery fails to reliably predict heparin bolus dose requirements. Anesth Analg 2010;111:849–55. Epub 2009 Oct 27
    CrossRefPubMedWeb of Science
  77. 77.↵
    1. Gravlee G,
    2. Davis R,
    3. Stammers A,
    4. et al
    . Cardiopulmonary Bypass: Principles and Practice. 3rd ed. Philadelphia: Lippincott Williams & Wilkins; 2008
  78. 78.↵
    1. Owings JT,
    2. Pollock ME,
    3. Gosselin RC,
    4. et al
    . Anticoagulation of children undergoing cardiopulmonary bypass is overestimated by current monitoring techniques. Arch Surg 2000;135:1042–47
    CrossRefPubMedWeb of Science
  79. 79.↵
    1. Helft G,
    2. Bartolomeo P,
    3. Zaman AG,
    4. et al
    . The heparin management test: a new device for monitoring anticoagulation during coronary intervention. Thrombosis Res 1999;96:481–85
    CrossRefPubMed
  80. 80.↵
    1. Tsimikas S,
    2. Beyer R,
    3. Hassankhani A
    . Relationship between the heparin management test and the HemoTec activated clotting time in patients undergoing percutaneous coronary intervention. J Thromb Thrombolysis 2001;11:217–21
    CrossRefPubMed
  81. 81.↵
    1. Ganter MT,
    2. Dalbert S,
    3. Graves K,
    4. et al
    . Monitoring activated clotting time for combined heparin and aprotinin application: an in vitro evaluation of a new aprotinin-insensitive test using SONOCLOT. Anesth Analg 2005;101:308–14
    CrossRefPubMed
  82. 82.↵
    1. Ganter MT,
    2. Monn A,
    3. Tavakoli R,
    4. et al
    . Monitoring activated clotting time for combined heparin and aprotinin application: in vivo evaluation of a new aprotinin-insensitive test using Sonoclot. Eur J Cardiothorac Surg 2006;30:278–84
    Abstract/FREE Full Text
  83. 83.↵
    1. Paniccia R,
    2. Fedi S,
    3. Carbonetto F,
    4. et al
    . Evaluation of a new point-of-care celite-activated clotting time analyzer in different clinical settings: the i-STAT celite-activated clotting time test. Anesthesiology 2003;99:54–59
    CrossRefPubMedWeb of Science
  84. 84.↵
    1. Bosch YP,
    2. Ganushchak YM,
    3. de Jong DS
    . Comparison of ACT point-of-care measurements: repeatability and agreement. Perfusion 2006;21:27–31
    Abstract/FREE Full Text
  85. 85.↵
    1. Espana F,
    2. Ratnoff OD
    . Activation of Hageman factor (factor XII) by sulfatides and other agents in the absence of plasma proteases. J Lab Clin Med 1983;102:31–45
    PubMed
  86. 86.↵
    1. Leyvi G,
    2. Shore-Lesserson L,
    3. Harrington D,
    4. et al
    . An investigation of a new activated clotting time “MAX-ACT” in patients undergoing extracorporeal circulation. Anesth Analg 2001;92:578–83
    CrossRefPubMed
  87. 87.
    1. Prisco D,
    2. Paniccia R
    . Point-of-care testing of hemostasis in cardiac surgery. Thromb J 2003;1:1
    CrossRefPubMed
  88. 88.↵
    1. Ganter MT,
    2. Hofer CK
    . Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation devices. Anesth Analg 2008;106:1366–75
    CrossRefPubMedWeb of Science
  89. 89.↵
    1. Wang JS,
    2. Lin CY,
    3. Hung WT,
    4. et al
    . Thromboelastogram fails to predict postoperative hemorrhage in cardiac patients. Ann Thorac Surg 1992;53:435–39
    CrossRefPubMedWeb of Science
  90. 90.↵
    1. Luddington RJ
    . Thrombelastography/thromboelastometry. Clin Lab Haematol 2005;27:81–90
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 33 (7)
American Journal of Neuroradiology
Vol. 33, Issue 7
1 Aug 2012
  • Table of Contents
  • Index by author
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Point-of-Care Testing for Anticoagulation Monitoring in Neuroendovascular Procedures
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
H.M. Hussein, A.L. Georgiadis, A.I. Qureshi
Point-of-Care Testing for Anticoagulation Monitoring in Neuroendovascular Procedures
American Journal of Neuroradiology Aug 2012, 33 (7) 1211-1220; DOI: 10.3174/ajnr.A2621

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Point-of-Care Testing for Anticoagulation Monitoring in Neuroendovascular Procedures
H.M. Hussein, A.L. Georgiadis, A.I. Qureshi
American Journal of Neuroradiology Aug 2012, 33 (7) 1211-1220; DOI: 10.3174/ajnr.A2621
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Brief Overview of Anticoagulant Medications
    • Methods of Measurement of Anticoagulation Intensity
    • Conclusions
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Off-Label Use of Drugs and Devices in the Neuroendovascular Suite
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Safety of Intrathecal Gadobutrol in Various Doses
  • Impact of Kidney Function on CNS Gadolinium Deposition in Patients Receiving Repeated Doses of Gadobutrol
  • Contrast-Induced Acute Kidney Injury in Radiologic Management of Acute Ischemic Stroke in the Emergency Setting
Show more Patient Safety

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire