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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleSpine Imaging and Spine Image-Guided Interventions

Validity of Intervertebral Bone Cement Infusion for Painful Vertebral Compression Fractures Based on the Presence of Vertebral Mobility

K. Yokoyama, M. Kawanishi, M. Yamada, H. Tanaka, Y. Ito, M. Hirano and T. Kuroiwa
American Journal of Neuroradiology January 2013, 34 (1) 228-232; DOI: https://doi.org/10.3174/ajnr.A3160
K. Yokoyama
aFrom the Department of Neurosurgery (K.Y., M.K., M.Y., H.T., Y.I., M.H.), Takeda General Hospital, Fushimi, Kyoto
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M. Kawanishi
aFrom the Department of Neurosurgery (K.Y., M.K., M.Y., H.T., Y.I., M.H.), Takeda General Hospital, Fushimi, Kyoto
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M. Yamada
aFrom the Department of Neurosurgery (K.Y., M.K., M.Y., H.T., Y.I., M.H.), Takeda General Hospital, Fushimi, Kyoto
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H. Tanaka
aFrom the Department of Neurosurgery (K.Y., M.K., M.Y., H.T., Y.I., M.H.), Takeda General Hospital, Fushimi, Kyoto
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Y. Ito
aFrom the Department of Neurosurgery (K.Y., M.K., M.Y., H.T., Y.I., M.H.), Takeda General Hospital, Fushimi, Kyoto
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M. Hirano
aFrom the Department of Neurosurgery (K.Y., M.K., M.Y., H.T., Y.I., M.H.), Takeda General Hospital, Fushimi, Kyoto
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T. Kuroiwa
bDepartments of Neurosurgery and Surgical Pathology (T.K.), Osaka Medical College, Takatsuki, Osaka, Japan.
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  • Fig 1.
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    Fig 1.

    Characteristic preoperative lateral radiographs of patient with VCF with pseudoarthrosis (A, flexion; B, extension). The collapsed L4 vertebral body shows dynamic mobility. Vertebral body height increased with extension stress.

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    Fig 2.

    Relationships between reduction in postoperative VAS and presence of vertebral mobility. We compared pain relief between the perforation and PVP groups. A, Patients with vertebral mobility; (B) patients without vertebral mobility.

Tables

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    Table 1:

    Baseline characteristics of patients treated for VCF

    PVP Group (n = 67)Perforation Group (n = 64)P Value
    Mean age (years)77.1 ± 7.276.7 ± 7.6.38
    Male:Female12:5511:53.99
    Mean interval (days)159.6 ± 250125.1 ± 204.74
    Treated level (T11–L2)52 (77.7%)49 (76.6%).89
    Preop VAS7.2 ± 1.67.5 ± 1.7.83
    Preop mobility of fracture23 (34.3%)32 (50%).08
    • Note:—Preop indicates preoperative.

    • View popup
    Table 2:

    Comparison of VAS between vertebral mobility and nonvertebral mobility

    PVPPerforation
    Vertebral Mobility +Vertebral Mobility −P ValueVertebral Mobility +Vertebral Mobility −P Value
    Preop7.17 ± 1.757.21 ± 1.58.8356.78 ± 1.837.42 ± 1.43.237
    Day 21.39 ± 1.671.65 ± 1.95.8183.28 ± 2.672.37 ± 2.38.193
    Day 71.45 ± 1.791.22 ± 1.64.6193.54 ± 2.702.00 ± 2.36.025
    Day 901.50 ± 1.601.46 ± 3.02.6583.21 ± 2.831.65 ± 2.06.037
    • Note:—Preop indicates preoperative.

    • View popup
    Table 3:

    Comparison of VAS and ADL scores between PVP and perforation groups based on the presence of vertebral mobility

    Vertebral Mobility +Vertebral Mobility −
    PVPPerforationP ValuePVPPerforationP Value
    VAS
        Preop7.17 ± 1.756.78 ± 1.83.637.21 ± 1.587.42 ± 1.43.622
        Day 21.39 ± 1.673.28 ± 2.67.0141.65 ± 1.952.37 ± 2.38.217
        Day 71.45 ± 1.793.54 ± 2.70.0041.22 ± 1.642.00 ± 2.36.243
        Day 901.50 ± 1.603.21 ± 2.83.0291.46 ± 3.021.65 ± 2.06.701
    ADL Score
        Preop1.65 ± 0.881.62 ± 0.74.8231.86 ± 0.851.96 ± 0.71.623
        Day 21.22 ± 0.901.74 ± 0.81.1091.44 ± 0.750.95 ± 0.72.151
        Day 901.04 ± 0.881.35 ± 0.81.1971.07 ± 1.070.82 ± 0.66.615
    • Note:—Preop indicates preoperative. ADL were evaluated using the following 5-point scale outlined in the text.

    • View popup
    Table 4:

    Incidence of new vertebral compression fracture after surgery

    PVP GroupPerforation GroupP Value
    Vertebral mobility +9/23 (39.1%), adjacent fx (6/9)1/32 (3.1%), adjacent fx (1/1)<.01
    Vertebral mobility −10/44 (22.7%), adjacent fx (7/10)4/19 (21.1%), adjacent fx (3/4).44
    Total19/67 (28.4%)5/51 (9.8%)<.01
    • Note:—Statistical analysis was performed with Fisher exact test. fx indicates fracture.

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American Journal of Neuroradiology: 34 (1)
American Journal of Neuroradiology
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K. Yokoyama, M. Kawanishi, M. Yamada, H. Tanaka, Y. Ito, M. Hirano, T. Kuroiwa
Validity of Intervertebral Bone Cement Infusion for Painful Vertebral Compression Fractures Based on the Presence of Vertebral Mobility
American Journal of Neuroradiology Jan 2013, 34 (1) 228-232; DOI: 10.3174/ajnr.A3160

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Validity of Intervertebral Bone Cement Infusion for Painful Vertebral Compression Fractures Based on the Presence of Vertebral Mobility
K. Yokoyama, M. Kawanishi, M. Yamada, H. Tanaka, Y. Ito, M. Hirano, T. Kuroiwa
American Journal of Neuroradiology Jan 2013, 34 (1) 228-232; DOI: 10.3174/ajnr.A3160
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