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Research ArticleLevel 1 EBM Expedited Publication
Open Access

Are There Differences between Macrocyclic Gadolinium Contrast Agents for Brain Tumor Imaging? Results of a Multicenter Intraindividual Crossover Comparison of Gadobutrol with Gadoteridol (the TRUTH Study)

K.R. Maravilla, M.P. Smith, J. Vymazal, M. Goyal, M. Herman, J.J. Baima, R. Babbel, M. Vaneckova, J. Žižka, C. Colosimo, M. Urbańczyk-Zawadzka, M. Mechl, A.K. Bag, S. Bastianello, E. Bueltmann, T. Hirai, T. Frattini, M.A. Kirchin and G. Pirovano
American Journal of Neuroradiology January 2015, 36 (1) 14-23; DOI: https://doi.org/10.3174/ajnr.A4154
K.R. Maravilla
aFrom the MR Research Laboratory (K.R.M.), University of Washington, Seattle, Washington
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M.P. Smith
bDepartment of Radiology (M.P.S.), Beth Israel Deaconess Medical Center, Boston, Massachusetts
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J. Vymazal
cDepartment of Radiology (J.V.), Na Homolce Hospital, Prague, Czech Republic
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M. Goyal
dSeaman Family MR Research Centre (M.G.), University of Calgary, Calgary, Alberta, Canada
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M. Herman
eDepartment of Radiology (M.H.), University Hospital Olomouc, Olomouc, Czech Republic
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J.J. Baima
fClinical Radiologists Service Corporation (J.J.B.), Memorial Medical Center, Springfield, Illinois
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R. Babbel
gGood Samaritan Regional Medical Center (R.B.), Corvallis, Oregon
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M. Vaneckova
hDepartment of Magnetic Resonance (M.V.), General University Hospital, Prague, Czech Republic
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J. Žižka
iDepartment of Diagnostic Radiology (J.Ž.), University Hospital Hradec Králové and Faculty of Medicine in Hradec Králové, Charles University, Prague, Czech Republic
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C. Colosimo
jIstituto di Radiologia (C.C.), Policlinico “Agostino Gemelli,” Rome, Italy
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M. Urbańczyk-Zawadzka
kDepartment of Radiology (M.U.-Z.), John Paul II Hospital, Krakow, Poland
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M. Mechl
lDepartment of Radiology (M.M.), University Hospital Brno-Bohunice, Brno, Czech Republic
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A.K. Bag
mDepartment of Radiology (A.K.B.), University of Alabama at Birmingham Medical Center, Birmingham, Alabama
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S. Bastianello
nDepartment of Neuroradiology (S.B), University of Pavia, Pavia, Italy
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E. Bueltmann
oInstitute for Diagnostic and Interventional Neuroradiology (E.B.), Hannover, Germany
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T. Hirai
pDepartment of Diagnostic Radiology (T.H.), Kumamoto University, Honjo, Kumamoto, Japan
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T. Frattini
qOspedale Valduce (T.F.), Como, Italy
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M.A. Kirchin
rGlobal Medical and Regulatory Affairs (M.A.K.), Bracco Imaging SpA, Milan, Italy
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G. Pirovano
sGlobal Medical and Regulatory Affairs (G.P.), Bracco Diagnostics, Monroe, New Jersey.
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American Journal of Neuroradiology: 36 (1)
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K.R. Maravilla, M.P. Smith, J. Vymazal, M. Goyal, M. Herman, J.J. Baima, R. Babbel, M. Vaneckova, J. Žižka, C. Colosimo, M. Urbańczyk-Zawadzka, M. Mechl, A.K. Bag, S. Bastianello, E. Bueltmann, T. Hirai, T. Frattini, M.A. Kirchin, G. Pirovano
Are There Differences between Macrocyclic Gadolinium Contrast Agents for Brain Tumor Imaging? Results of a Multicenter Intraindividual Crossover Comparison of Gadobutrol with Gadoteridol (the TRUTH Study)
American Journal of Neuroradiology Jan 2015, 36 (1) 14-23; DOI: 10.3174/ajnr.A4154

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Are There Differences between Macrocyclic Gadolinium Contrast Agents for Brain Tumor Imaging? Results of a Multicenter Intraindividual Crossover Comparison of Gadobutrol with Gadoteridol (the TRUTH Study)
K.R. Maravilla, M.P. Smith, J. Vymazal, M. Goyal, M. Herman, J.J. Baima, R. Babbel, M. Vaneckova, J. Žižka, C. Colosimo, M. Urbańczyk-Zawadzka, M. Mechl, A.K. Bag, S. Bastianello, E. Bueltmann, T. Hirai, T. Frattini, M.A. Kirchin, G. Pirovano
American Journal of Neuroradiology Jan 2015, 36 (1) 14-23; DOI: 10.3174/ajnr.A4154
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  • Comparison of Dynamic Contrast-Enhancement Parameters between Gadobutrol and Gadoterate Meglumine in Posttreatment Glioma: A Prospective Intraindividual Study
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  • Comparison of Gadoterate Meglumine and Gadobutrol in the MRI Diagnosis of Primary Brain Tumors: A Double-Blind Randomized Controlled Intraindividual Crossover Study (the REMIND Study)
  • The Benefits of High Relaxivity for Brain Tumor Imaging: Results of a Multicenter Intraindividual Crossover Comparison of Gadobenate Dimeglumine with Gadoterate Meglumine (The BENEFIT Study)
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