Article Figures & Data
Tables
MCI Measure b0 bCog bEdu bAge (SE; P) bAPOE (SE; P) bSex (SE; P) Hippocampus −1.83a −0.13a 0.03 0.00 (.02; .8) −0.40a (.20; .045) −0.29 (.20; .1) Amygdala −1.57a −0.15a 0.01 0.03 (.02; .1) −0.94a (0.21; 7 × 10−6) −0.98a (.21; 2 × 10−6) Entorhinal −1.78a −0.12a 0.00 0.04a (.02; .006) −0.44a (.17; .011) −0.54a (.17; .002) Inferior parietal −0.91a −0.08a 0.02 0.06a (.01; 2 × 10−6) −0.28a (.14; .040) −0.40a (.14; .004) Middle temporal −1.40a −0.11a 0.00 0.07a (.02; 9 × 10−6) −0.28 (.18; .1) −0.52a (.17; .003) Med-orbito-frontal −0.78a −0.04a 0.04a 0.02a (.01; .023) 0.03 (.11; .8) −0.24a (.11; .026) Whole brain −0.74a −0.04a 0.01 0.02a (.01; 4 × 10−4) −0.09 (.08; .2) −0.17a (.08; .022) CDR-SB 0.46a – 0.01 0.01 (.01; .4) 0.38a (.11; 6 × 10−4) 0.26a (.11; .021) ADAS-Cog 0.49a – 0.00 0.03 (.03; .3) 0.72a (.31; .022) 1.40a (.32; 2 × 10−5) MMSE −0.35a – 0.02 0.02 (.02; .4) −0.81a (.20; 4 × 10−5) −0.34 (.20; .1) Note:—See Table 2 for units and key.
↵a Values significant at P ≤ .05.
ROIs: N = 273; mean age = 76.65 years; mean ADAS-Cog = 11.68; mean years education = 15.61. Cognitive: N = 211; mean age = 76.84 years; mean years education = 15.63.