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Research ArticleNeurointervention

Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years

M. van Eijck, R.S. Bechan, M. Sluzewski, J.P. Peluso, G. Roks and W.J. van Rooij
American Journal of Neuroradiology November 2015, 36 (11) 2108-2113; DOI: https://doi.org/10.3174/ajnr.A4410
M. van Eijck
aFrom the Departments of Neurology (M.v.E., G.R.)
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R.S. Bechan
bRadiology (R.S.B., M.S., J.P.P., W.J.v.R.), Sint Elisabeth Ziekenhuis, Tilburg, the Netherlands.
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M. Sluzewski
bRadiology (R.S.B., M.S., J.P.P., W.J.v.R.), Sint Elisabeth Ziekenhuis, Tilburg, the Netherlands.
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J.P. Peluso
bRadiology (R.S.B., M.S., J.P.P., W.J.v.R.), Sint Elisabeth Ziekenhuis, Tilburg, the Netherlands.
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G. Roks
aFrom the Departments of Neurology (M.v.E., G.R.)
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W.J. van Rooij
bRadiology (R.S.B., M.S., J.P.P., W.J.v.R.), Sint Elisabeth Ziekenhuis, Tilburg, the Netherlands.
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Article Figures & Data

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    Fig 1.

    Follow-up scheme of 154 patients with a basilar tip aneurysm.

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    Fig 2.

    A 41-year-old man with a coiled ruptured basilar tip aneurysm in 1997 and a rebleed 15 years later. A, Angiography in 2006, 9 years after coiling in 1997, shows an adequately occluded basilar tip aneurysm. B, CT in 2012 demonstrates a rebleed from the basilar tip aneurysm. C, Angiography reveals regrowth of the aneurysm (arrow). D, After additional coiling, the aneurysm is completely occluded (arrow).

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    Fig 3.

    Timing of first retreatments in 37 patients with reopened basilar tip aneurysms.

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    Fig 4.

    Timing of retreatments in 15 patients with coiled basilar tip aneurysms and >1 recurrence.

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    Fig 5.

    Serial MR images of a 40-year-old man with a coiled ruptured basilar tip aneurysm in 2003. A, Transversal T2-weighted MR image from December 2003 shows a basilar tip aneurysm 6 months after coiling. B, MR imaging in May 2008 shows enlargement of the aneurysm and compression of the brain stem. C, MR imaging in March 2009 shows further growth, now with edema in the brain stem. D, MR imaging in December 2009 shows a rapid increase in size with enormous compression of the brain stem. The patient died 1 month later.

Tables

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    Table 1:

    Univariate analysis of risk factors for retreatment of coiled basilar tip aneurysms in 144 patients

    No Recurrence (n = 107)Recurrence (n = 37)OR (95% CI)P Value
    Median age at first treatment (yr)54460.97 (0.9–1.0).13
    Male sex25 (23%)16 (43%)2.6 (1.2–5.6).02
    Median aneurysm size (mm)9151.1 (1.1–1.2)<.001
    Size of aneurysm in quintilesa
        Quintile 2 versus 10.9 (0.2–3.3)
        Quintile 3 versus 10.9 (0.2–3.3)
        Quintile 4 versus 11.6 (0.4–6.3)
        Quintile 5 versus 18.5 (2.5–29.3)
    Ruptured aneurysm88 (82%)14 (38%)0.8 (0.3–1.9).62
    Median follow-up (yr)10.5101.0 (0.98–1.14).20
    • ↵a Size range in quintiles: quintile 1 = 2–5 mm; quintile 2 = 6–8 mm; quintile 3 = 9–12 mm; quintile 4 = 13–15 mm; quintile 5 = 16–30 mm.

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    Table 2:

    Characteristics of 6 patients with progressive mass effect by continuous growth of the basilar tip aneurysm despite (repeat) coiling

    Date of First TreatmentSex, Age (yr)SAHFirst Signs of Mass EffectCompression OrganNo.of CoilingsDeathFollow-Up (yr)
    Jan 10, 1996M, 52YesJanuary 1996Brain stem1Yes0.5
    June 5, 1996M, 39YesMay 2008Brain stem5No11.8
    June 18, 2001F, 69YesSeptember 2004Brain stem1Yes3.3
    July 27, 2001M, 39YesMarch 2009Brain stem5Yes8.4
    November 5, 2001M, 58YesJuly 2012Brain stem5Yes12.5
    May 30, 2002M, 49NoOctober 2002Optic chiasm2Yes0.5
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American Journal of Neuroradiology: 36 (11)
American Journal of Neuroradiology
Vol. 36, Issue 11
1 Nov 2015
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Cite this article
M. van Eijck, R.S. Bechan, M. Sluzewski, J.P. Peluso, G. Roks, W.J. van Rooij
Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years
American Journal of Neuroradiology Nov 2015, 36 (11) 2108-2113; DOI: 10.3174/ajnr.A4410

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Clinical and Imaging Follow-Up of Patients with Coiled Basilar Tip Aneurysms Up to 20 Years
M. van Eijck, R.S. Bechan, M. Sluzewski, J.P. Peluso, G. Roks, W.J. van Rooij
American Journal of Neuroradiology Nov 2015, 36 (11) 2108-2113; DOI: 10.3174/ajnr.A4410
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