Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • Video Articles
    • AJNR Case Collection
    • Case of the Week Archive
    • Case of the Month Archive
    • Classic Case Archive
  • Special Collections
    • AJNR Awards
    • Low-Field MRI
    • Alzheimer Disease
    • ASNR Foundation Special Collection
    • Photon-Counting CT
    • View All
  • Multimedia
    • AJNR Podcasts
    • AJNR SCANtastic
    • Trainee Corner
    • MRI Safety Corner
    • Imaging Protocols
  • For Authors
    • Submit a Manuscript
    • Submit a Video Article
    • Submit an eLetter to the Editor/Response
    • Manuscript Submission Guidelines
    • Statistical Tips
    • Fast Publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Imaging Protocol Submission
    • Author Policies
  • About Us
    • About AJNR
    • Editorial Board
    • Editorial Board Alumni
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleSpine Imaging and Spine Image-Guided Interventions
Open Access

T1ρ and T2 Mapping of the Intervertebral Disk: Comparison of Different Methods of Segmentation

R. Menezes-Reis, C.E.G. Salmon, C.S. Carvalho, G.P. Bonugli, C.B. Chung and M.H. Nogueira-Barbosa
American Journal of Neuroradiology March 2015, 36 (3) 606-611; DOI: https://doi.org/10.3174/ajnr.A4125
R. Menezes-Reis
aFrom the Division of Radiology (R.M.-R., G.P.B., C.S.C., M.H.N.-B.), Ribeirão Preto Medical School
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C.E.G. Salmon
bDepartment of Physics (C.E.G.S.), Ribeirão Preto Philosophy and Sciences School, University of São Paulo, São Paulo, Brazil
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C.S. Carvalho
aFrom the Division of Radiology (R.M.-R., G.P.B., C.S.C., M.H.N.-B.), Ribeirão Preto Medical School
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
G.P. Bonugli
aFrom the Division of Radiology (R.M.-R., G.P.B., C.S.C., M.H.N.-B.), Ribeirão Preto Medical School
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
C.B. Chung
cDepartment of Radiology (C.B.C.), VA San Diego Healthcare System, San Diego, California.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
M.H. Nogueira-Barbosa
aFrom the Division of Radiology (R.M.-R., G.P.B., C.S.C., M.H.N.-B.), Ribeirão Preto Medical School
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

REFERENCES

  1. 1.↵
    1. Maus TP,
    2. Aprill CN
    . Lumbar diskogenic pain, provocation diskography, and imaging correlates. Radiol Clin North Am 2012;50:681–704
    CrossRefPubMed
  2. 2.↵
    1. Wassenaar M,
    2. van Rijn RM,
    3. van Tulder MW, et al
    . Magnetic resonance imaging for diagnosing lumbar spinal pathology in adult patients with low back pain or sciatica: a diagnostic systematic review. Eur Spine J 2012;21:220–27
    CrossRefPubMed
  3. 3.↵
    1. Lotz JC,
    2. Haughton V,
    3. Boden SD, et al
    . New treatments and imaging strategies in degenerative disease of the intervertebral disks. Radiology 2012;264:6–19
    CrossRefPubMed
  4. 4.↵
    1. Majumdar S
    . Magnetic resonance imaging and spectroscopy of the intervertebral disc. NMR Biomed 2006;19:894–903
    CrossRefPubMed
  5. 5.↵
    1. Pham DL,
    2. Xu C,
    3. Prince JL
    . Current methods in medical image segmentation. Annu Rev Biomed Eng 2000;2:315–37
    CrossRefPubMedWeb of Science
  6. 6.↵
    1. Mwale F,
    2. Iatridis JC,
    3. Antoniou J
    Quantitative MRI as a diagnostic tool of intervertebral disc matrix composition and integrity. Eur Spine J 2008;17(suppl 4):432–40
    PubMedWeb of Science
  7. 7.↵
    1. Marinelli NL,
    2. Haughton VM,
    3. Anderson PA
    . T2 relaxation times correlated with stage of lumbar intervertebral disk degeneration and patient age. AJNR Am J Neuroradiol 2010;31:1278–82
    Abstract/FREE Full Text
  8. 8.↵
    1. Haneder S,
    2. Apprich SR,
    3. Schmitt B, et al
    . Assessment of glycosaminoglycan content in intervertebral discs using chemical exchange saturation transfer at 3.0 Tesla: preliminary results in patients with low-back pain. Eur Radiol 2013;23:861–68
    CrossRefPubMed
  9. 9.↵
    1. Trattnig S,
    2. Stelzeneder D,
    3. Goed S, et al
    . Lumbar intervertebral disc abnormalities: comparison of quantitative T2 mapping with conventional MR at 3.0 T. Eur Radiol 2010;20:2715–22
    CrossRefPubMed
  10. 10.↵
    1. Michopoulou S,
    2. Costaridou L,
    3. Vlychou M, et al
    . Texture-based quantification of lumbar intervertebral disc degeneration from conventional T2-weighted MRI. Acta Radiol 2011;52:91–98
    Abstract/FREE Full Text
  11. 11.↵
    1. Chan WC,
    2. Sze KL,
    3. Samartzis D, et al
    . Structure and biology of the intervertebral disk in health and disease. Orthop Clin North Am 2011;42:447–64, vii
    CrossRefPubMed
  12. 12.↵
    1. Blumenkrantz G,
    2. Li X,
    3. Han ET, et al
    . A feasibility study of in vivo T1rho imaging of the intervertebral disc. Magn Reson Imaging 2006;24:1001–07
    CrossRefPubMedWeb of Science
  13. 13.↵
    1. Auerbach JD,
    2. Johannessen W,
    3. Borthakur A, et al
    . In vivo quantification of human lumbar disc degeneration using T1(rho)-weighted magnetic resonance imaging. Eur Spine J 2006;15(suppl 3):S338–44
    CrossRefPubMedWeb of Science
  14. 14.↵
    1. Pfirrmann CW,
    2. Metzdorf A,
    3. Zanetti M, et al
    . Magnetic resonance classification of lumbar intervertebral disc degeneration. Spine (Phila Pa 1976) 2001;26:1873–78
    CrossRef
  15. 15.↵
    1. Stelzeneder D,
    2. Welsch GH,
    3. Kovács BK, et al
    . Quantitative T2 evaluation at 3.0T compared to morphological grading of the lumbar intervertebral disc: a standardized evaluation approach in patients with low back pain. Eur J Radiol 2012;81:324–30
    CrossRefPubMed
  16. 16.↵
    1. Sharma A,
    2. Parsons M,
    3. Pilgram T
    . Temporal interactions of degenerative changes in individual components of the lumbar intervertebral discs: a sequential magnetic resonance imaging study in patients less than 40 years of age. Spine (Phila Pa 1976) 2011;36:1794–800
    CrossRef
  17. 17.↵
    1. Del Grande F,
    2. Maus TP,
    3. Carrino JA
    . Imaging the intervertebral disk: age-related changes, herniations, and radicular pain. Radiol Clin North Am 2012;50:629–49
    CrossRefPubMed
  18. 18.↵
    1. Issy AC,
    2. Castania V,
    3. Castania M, et al
    . Experimental model of intervertebral disc degeneration by needle puncture in Wistar rats. Braz J MedBiol Res 2013;46:235–44
    CrossRef
  19. 19.↵
    1. Antoniou J,
    2. Pike GB,
    3. Steffen T, et al
    . Quantitative magnetic resonance imaging in the assessment of degenerative disc disease. Magn Reson Med 1998;40:900–07
    CrossRefPubMed
  20. 20.↵
    1. Zuo J,
    2. Joseph GB,
    3. Li X, et al
    . In vivo intervertebral disc characterization using magnetic resonance spectroscopy and T1ρ imaging: association with discography and Oswestry Disability Index and Short Form-36 Health Survey. Spine (Phila Pa 1976) 2012;37:214–21
    CrossRef
  21. 21.↵
    1. Antoniou J,
    2. Epure LM,
    3. Michalek AJ, et al
    . Analysis of quantitative magnetic resonance imaging and biomechanical parameters on human discs with different grades of degeneration. J Magn Reson Imaging 2013;38:1402–14
    CrossRefPubMed
  22. 22.↵
    1. Ding WY,
    2. Yang DL,
    3. Cao LZ, et al
    . Interverterbal disc degeneration and bone density in degenerative lumbar scoliosis: a comparative study between patients with degenerative lumbar scoliosis and patients with lumbar stenosis. Chin Med J (Engl) 2011;124:3875–78
    PubMed
  23. 23.↵
    1. Homminga J,
    2. Lehr AM,
    3. Meijer GJ, et al
    . Posteriorly directed shear loads and disc degeneration affect the torsional stiffness of spinal motion segments: a biomechanical modeling study. Spine (Phila Pa 1976) 2013;38:E1313–19
    CrossRef
  24. 24.↵
    1. Gervais J,
    2. Périé D,
    3. Parent S, et al
    . MRI signal distribution within the intervertebral disc as a biomarker of adolescent idiopathic scoliosis and spondylolisthesis. BMC Musculoskelet Disord 2012;13:239
    CrossRefPubMed
  25. 25.↵
    1. Igbinedion BO,
    2. Akhigbe A
    . Correlations of radiographic findings in patients with low back pain. Niger Med J 2011;52:28–34
    PubMed
  26. 26.↵
    1. Iguchi T,
    2. Nishida K,
    3. Ozaki T, et al
    . Grade three disc degeneration is a critical stage for anterior spondylolisthesis in lumbar spine. Eur Spine J 2012;21:2134–39
    CrossRefPubMed
  27. 27.↵
    1. Borthakur A,
    2. Maurer PM,
    3. Fenty M, et al
    . T1ρ magnetic resonance imaging and discography pressure as novel biomarkers for disc degeneration and low back pain. Spine (Phila Pa 1976) 2011;36:2190–96
    CrossRef
  28. 28.↵
    1. Stelzeneder D,
    2. Welsch GH,
    3. Kovács BK, et al
    . Quantitative T2 evaluation at 3.0T compared to morphological grading of the lumbar intervertebral disc: a standardized evaluation approach in patients with low back pain. Eur J Radiol 2012;81:324–30
    CrossRefPubMed
  29. 29.↵
    1. Welsch GH,
    2. Trattnig S,
    3. Paternostro-Sluga T, et al
    . Parametric T2 and T2* mapping techniques to visualize intervertebral disc degeneration in patients with low back pain: initial results on the clinical use of 3.0 Tesla MRI. Skeletal Radiol 2011;40:543–51
    CrossRefPubMed
  30. 30.↵
    1. Zobel BB,
    2. Vadalà G,
    3. Del Vescovo R, et al
    . T1ρ magnetic resonance imaging quantification of early lumbar intervertebral disc degeneration in healthy young adults. Spine (Phila Pa 1976) 2012;37:1224–30
    CrossRef
  31. 31.↵
    1. Wang YX,
    2. Zhao F,
    3. Griffith JF, et al
    . T1rho and T2 relaxation times for lumbar disc degeneration: an in vivo comparative study at 3.0-Tesla MRI. Eur Radiol 2013;23:228–34
    CrossRefPubMed
  32. 32.↵
    1. Wang YX,
    2. Zhao F,
    3. Yuan J, et al
    . Accelerated T1rho relaxation quantification in intervertebral disc using limited spin-lock times. Quant Imaging Med Surg 2013;3:54–58
    PubMed
  33. 33.↵
    1. Pattappa G,
    2. Li Z,
    3. Peroglio M, et al
    . Diversity of intervertebral disc cells: phenotype and function. J Anat 2012;221:480–96
    CrossRefPubMedWeb of Science
  34. 34.↵
    1. Niu G,
    2. Yang J,
    3. Wang R, et al
    . MR imaging assessment of lumbar intervertebral disk degeneration and age-related changes: apparent diffusion coefficient versus T2 quantitation. AJNR Am J Neuroradiol 2011;32:1617–23
    Abstract/FREE Full Text
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 36 (3)
American Journal of Neuroradiology
Vol. 36, Issue 3
1 Mar 2015
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
T1ρ and T2 Mapping of the Intervertebral Disk: Comparison of Different Methods of Segmentation
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
R. Menezes-Reis, C.E.G. Salmon, C.S. Carvalho, G.P. Bonugli, C.B. Chung, M.H. Nogueira-Barbosa
T1ρ and T2 Mapping of the Intervertebral Disk: Comparison of Different Methods of Segmentation
American Journal of Neuroradiology Mar 2015, 36 (3) 606-611; DOI: 10.3174/ajnr.A4125

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
T1ρ and T2 Mapping of the Intervertebral Disk: Comparison of Different Methods of Segmentation
R. Menezes-Reis, C.E.G. Salmon, C.S. Carvalho, G.P. Bonugli, C.B. Chung, M.H. Nogueira-Barbosa
American Journal of Neuroradiology Mar 2015, 36 (3) 606-611; DOI: 10.3174/ajnr.A4125
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • Acknowledgments
    • Footnotes
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • Variability of T2-Relaxation Times of Healthy Lumbar Intervertebral Discs is More Homogeneous within an Individual Than across Healthy Individuals
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • Management Outcomes For VO Spine Biopsy
  • Characteristics of SIH Type I Culprit Lesions
  • Advanced Imaging of Type 2 Spinal CSF Leaks
Show more Spine Imaging and Spine Image-Guided Interventions

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editor's Choice
  • Fellows' Journal Club
  • Letters to the Editor
  • Video Articles

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

More from AJNR

  • Trainee Corner
  • Imaging Protocols
  • MRI Safety Corner
  • Book Reviews

Multimedia

  • AJNR Podcasts
  • AJNR Scantastics

Resources

  • Turnaround Time
  • Submit a Manuscript
  • Submit a Video Article
  • Submit an eLetter to the Editor/Response
  • Manuscript Submission Guidelines
  • Statistical Tips
  • Fast Publishing of Accepted Manuscripts
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Author Policies
  • Become a Reviewer/Academy of Reviewers
  • News and Updates

About Us

  • About AJNR
  • Editorial Board
  • Editorial Board Alumni
  • Alerts
  • Permissions
  • Not an AJNR Subscriber? Join Now
  • Advertise with Us
  • Librarian Resources
  • Feedback
  • Terms and Conditions
  • AJNR Editorial Board Alumni

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire