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Index by author

November 01, 2016; Volume 37,Issue 11

  1. Guez, D.

    1. EDITOR'S CHOICEADULT BRAIN
      Early Biomarkers from Conventional and Delayed-Contrast MRI to Predict the Response to Bevacizumab in Recurrent High-Grade Gliomas
      D. Daniels, D. Guez, D. Last, C. Hoffmann, D. Nass, A. Talianski, G. Tsarfaty, S. Salomon, A.A. Kanner, D.T. Blumenthal, F. Bokstein, S. Harnof, D. Yekutieli, S. Zamir, Z.R. Cohen, L. Zach and Y. Mardor
      American Journal of Neuroradiology November 2016, 37 (11) 2003-2009; DOI: https://doi.org/10.3174/ajnr.A4866

      Twenty-four patients with recurrent high-grade gliomas were scanned before and during bevacizumab treatment with standard and delayed-contrast MRI. The mean change in lesion volumes of responders (overall survival, >1 year) and nonresponders (overall survival, <1 year) was evaluated. Treatment-response-assessment maps (TRAMs) were calculated by subtracting conventional T1WI (acquired a few minutes postcontrast) from delayed T1WI (acquired with a delay of >1 hour postcontrast). These maps depict the spatial distribution of contrast accumulation and clearance. At progression, the increase in lesion volumes in delayed-contrast MR imaging was 37.5% higher than the increase in conventional T1WI. The authors conclude that the benefit of standard and delayed-contrast MRI for assessing and predicting the response to bevacizumab was demonstrated and that the increased sensitivity of delayed-contrast MRI reflects its potential contribution to the management of bevacizumab-treated patients with recurrent HGG.

  2. Gunderson, T.

    1. INTERVENTIONAL
      Open Access
      Wall Apposition Is a Key Factor for Aneurysm Occlusion after Flow Diversion: A Histologic Evaluation in 41 Rabbits
      A. Rouchaud, C. Ramana, W. Brinjikji, Y.-H. Ding, D. Dai, T. Gunderson, J. Cebral, D.F. Kallmes and R. Kadirvel
      American Journal of Neuroradiology November 2016, 37 (11) 2087-2091; DOI: https://doi.org/10.3174/ajnr.A4848

  3. Gupta, V.

    1. Embryologic Anatomic Variations: Challenges in Intra-Arterial Chemotherapy for Intraocular Retinoblastoma
      C. Paruthi, V. Gupta and N. Khandelwal
      American Journal of Neuroradiology November 2016, 37 (11) E71-E72; DOI: https://doi.org/10.3174/ajnr.A4905

  4. Ha, E.J.

    1. INTERVENTIONAL
      Prophylactic Antiplatelet Medication in Endovascular Treatment of Intracranial Aneurysms: Low-Dose Prasugrel versus Clopidogrel
      E.J. Ha, W.S. Cho, J.E. Kim, Y.D. Cho, H.H. Choi, T. Kim, J.S. Bang, G. Hwang, O.K. Kwon, C.W. Oh, M.H. Han and H.S. Kang
      American Journal of Neuroradiology November 2016, 37 (11) 2060-2065; DOI: https://doi.org/10.3174/ajnr.A4864

  5. Haacke, E.M.

    1. EXTRACRANIAL VASCULAR
      Open Access
      Validation of a Hemodynamic Model for the Study of the Cerebral Venous Outflow System Using MR Imaging and Echo-Color Doppler Data
      G. Gadda, A. Taibi, F. Sisini, M. Gambaccini, S.K. Sethi, D.T. Utriainen, E.M. Haacke, P. Zamboni and M. Ursino
      American Journal of Neuroradiology November 2016, 37 (11) 2100-2109; DOI: https://doi.org/10.3174/ajnr.A4860

  6. Han, M.H.

    1. INTERVENTIONAL
      Prophylactic Antiplatelet Medication in Endovascular Treatment of Intracranial Aneurysms: Low-Dose Prasugrel versus Clopidogrel
      E.J. Ha, W.S. Cho, J.E. Kim, Y.D. Cho, H.H. Choi, T. Kim, J.S. Bang, G. Hwang, O.K. Kwon, C.W. Oh, M.H. Han and H.S. Kang
      American Journal of Neuroradiology November 2016, 37 (11) 2060-2065; DOI: https://doi.org/10.3174/ajnr.A4864

  7. Harnof, S.

    1. EDITOR'S CHOICEADULT BRAIN
      Early Biomarkers from Conventional and Delayed-Contrast MRI to Predict the Response to Bevacizumab in Recurrent High-Grade Gliomas
      D. Daniels, D. Guez, D. Last, C. Hoffmann, D. Nass, A. Talianski, G. Tsarfaty, S. Salomon, A.A. Kanner, D.T. Blumenthal, F. Bokstein, S. Harnof, D. Yekutieli, S. Zamir, Z.R. Cohen, L. Zach and Y. Mardor
      American Journal of Neuroradiology November 2016, 37 (11) 2003-2009; DOI: https://doi.org/10.3174/ajnr.A4866

      Twenty-four patients with recurrent high-grade gliomas were scanned before and during bevacizumab treatment with standard and delayed-contrast MRI. The mean change in lesion volumes of responders (overall survival, >1 year) and nonresponders (overall survival, <1 year) was evaluated. Treatment-response-assessment maps (TRAMs) were calculated by subtracting conventional T1WI (acquired a few minutes postcontrast) from delayed T1WI (acquired with a delay of >1 hour postcontrast). These maps depict the spatial distribution of contrast accumulation and clearance. At progression, the increase in lesion volumes in delayed-contrast MR imaging was 37.5% higher than the increase in conventional T1WI. The authors conclude that the benefit of standard and delayed-contrast MRI for assessing and predicting the response to bevacizumab was demonstrated and that the increased sensitivity of delayed-contrast MRI reflects its potential contribution to the management of bevacizumab-treated patients with recurrent HGG.

  8. Hayashi, K.

    1. ADULT BRAIN
      Image Quality Required for the Diagnosis of Skull Fractures Using Head CT: A Comparison of Conventional and Improved Reconstruction Kernels
      S. Takagi, M. Koyama, K. Hayashi and T. Kawauchi
      American Journal of Neuroradiology November 2016, 37 (11) 1992-1995; DOI: https://doi.org/10.3174/ajnr.A4861

  9. Hernandez-castillo, C.R.

    1. ADULT BRAIN
      Open Access
      Ataxia Severity Correlates with White Matter Degeneration in Spinocerebellar Ataxia Type 7
      C.R. Hernandez-Castillo, I. Vaca-Palomares, F. Barrios, L. Martinez, M.-C. Boll and J. Fernandez-Ruiz
      American Journal of Neuroradiology November 2016, 37 (11) 2050-2054; DOI: https://doi.org/10.3174/ajnr.A4903

  10. Herweh, C.

    1. EDITOR'S CHOICEINTERVENTIONAL
      Mechanical Thrombectomy in Patients with Acute Ischemic Stroke and Lower NIHSS Scores: Recanalization Rates, Periprocedural Complications, and Clinical Outcome
      J. Pfaff, C. Herweh, M. Pham, S. Schönenberger, S. Nagel, P.A. Ringleb, M. Bendszus and M. Möhlenbruch
      American Journal of Neuroradiology November 2016, 37 (11) 2066-2071; DOI: https://doi.org/10.3174/ajnr.A4862

      This is a retrospective analysis of 484 patients in a prospectively collected stroke data base. The inclusion criteria were anterior circulation ischemic stroke treated with mechanical thrombectomy at a single institution between September 2010 and October 2015 with an NIHSS score of ≤8. The purpose was to assess the clinical and interventional data in patients treated with mechanical thrombectomy in case of ischemic stroke with mild-to-moderate symptoms (n = 33). Recanalization (TICI 2b–3) was achieved in 26 (78.7%) patients. Two cases of symptomatic intracranial hemorrhage occurred. Favorable (mRS 0–2) and moderate (mRS 0–3) clinical 90-day outcome was achieved in 63.6% and 90.9% of patients, respectively. The authors conclude that the clinical outcome of patients undergoing mechanical thrombectomy for acute ischemic mild stroke due to large-vessel occlusion is predominately favorable, even in a prolonged time window.

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