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Research ArticleAdult Brain
Open Access

Comparison of High-Resolution MR Imaging and Digital Subtraction Angiography for the Characterization and Diagnosis of Intracranial Artery Disease

N.J. Lee, M.S. Chung, S.C. Jung, H.S. Kim, C.-G. Choi, S.J. Kim, D.H. Lee, D.C. Suh, S.U. Kwon, D.-W. Kang and J.S. Kim
American Journal of Neuroradiology December 2016, 37 (12) 2245-2250; DOI: https://doi.org/10.3174/ajnr.A4950
N.J. Lee
aFrom the Department of Radiology and Research Institute of Radiology (N.J.L., M.S.C., S.C.J., H.S.K., C.-G.C., S.J.K., D.H.L., D.C.S.)
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M.S. Chung
aFrom the Department of Radiology and Research Institute of Radiology (N.J.L., M.S.C., S.C.J., H.S.K., C.-G.C., S.J.K., D.H.L., D.C.S.)
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S.C. Jung
aFrom the Department of Radiology and Research Institute of Radiology (N.J.L., M.S.C., S.C.J., H.S.K., C.-G.C., S.J.K., D.H.L., D.C.S.)
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H.S. Kim
aFrom the Department of Radiology and Research Institute of Radiology (N.J.L., M.S.C., S.C.J., H.S.K., C.-G.C., S.J.K., D.H.L., D.C.S.)
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C.-G. Choi
aFrom the Department of Radiology and Research Institute of Radiology (N.J.L., M.S.C., S.C.J., H.S.K., C.-G.C., S.J.K., D.H.L., D.C.S.)
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S.J. Kim
aFrom the Department of Radiology and Research Institute of Radiology (N.J.L., M.S.C., S.C.J., H.S.K., C.-G.C., S.J.K., D.H.L., D.C.S.)
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D.H. Lee
aFrom the Department of Radiology and Research Institute of Radiology (N.J.L., M.S.C., S.C.J., H.S.K., C.-G.C., S.J.K., D.H.L., D.C.S.)
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D.C. Suh
aFrom the Department of Radiology and Research Institute of Radiology (N.J.L., M.S.C., S.C.J., H.S.K., C.-G.C., S.J.K., D.H.L., D.C.S.)
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S.U. Kwon
bDepartment of Neurology (S.U.K., D.-W.K., J.S.K.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
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D.-W. Kang
bDepartment of Neurology (S.U.K., D.-W.K., J.S.K.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
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J.S. Kim
bDepartment of Neurology (S.U.K., D.-W.K., J.S.K.), University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.
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    Fig 1.

    Measurements of the degree of stenosis and minimal luminal diameter in both DSA and HR-MR. The degree of stenosis is 73.9% on HR-MR (normal luminal diameter, 3.18 mm; minimal luminal diameter, 0.83 mm) and 72.7% on DSA (normal luminal diameter, 2.86 mm; minimal luminal diameter, 0.78 mm).

Tables

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    Table 1:

    Comparison of the degree of stenosis and the minimal luminal diameter

    Degree of Stenosis (%)Minimal Luminal Diameter (mm)
    Observer 1Observer 2Observer 1Observer 2
    DSAa71.72 ± 21.21b70.64 ± 23.18b0.50 ± 0.40c0.51 ± 0.42c
        Interobserver agreement0.930 (0.868–0.963)0.916 (0.838–0.956)
    HR-MRa74.27 ± 20.39b70.42 ± 23.12b0.61 ± 0.49c0.59 ± 0.48c
        Interobserver agreement0.909 (0.828–0.952)0.915 (0.836–0.956)
    Agreement
        Continuous valuesd0.937 (0.882–0.967)0.943 (0.892–0.970)0.892 (0.791–0.944)0.949 (0.902–0.974)
        Classified stenosise0.548 (0.310–0.785)0.614 (0.403–0.825)
    Correlation
        Continuous valuesf0.861 (P < .001)0.892 (P < .001)0.816 (P < .001)0.879 (P < .001)
        Classified stenosisf0.773 (P < .001)0.766 (P < .001)
    • ↵a Data indicate the mean ± SD.

    • ↵b There were no significant differences between DSA and HR-MR (P > .05).

    • ↵c There were significant differences between DSA and HR-MR (P < .05).

    • ↵d Agreement refers to the interclass correlation coefficients between DSA and HR-MR, and data in parentheses indicate 95% confidence intervals.

    • ↵e Agreement refers to the κ values between DSA and HR-MR, and data in parentheses indicate 95% confidence intervals.

    • ↵f Correlation refers to the Spearman R values between DSA and HR-MR.

    • View popup
    Table 2:

    Interobserver and intermodality diagnostic agreement

    Diagnostic AgreementaAgreement RatiobDisagreement RatiobUndetermined Diagnosisc
    DSAd0.643 (0.458–0.828)73.0% (27/37)27.0% (10/27)5.41 %/16.22 %
    HR-MRd0.818 (0.670–0.966)86.5% (32/37)13.5% (5/37)2.70 %/5.41 %
    Observer 1e0.704 (0.528–0.881)78.4% (29/37)21.6% (8/37)
    Observer 2e0.579 (0.390–0.768)67.6% (25/37)32.4% (12/37)
    • ↵a Agreement refers to κ values between DSA and HR-MR, and data in parentheses indicate 95% confidence intervals.

    • ↵b Data in parentheses indicate the numbers of agreed or disagreed cases compared with the total number of cases in the diagnosis.

    • ↵c The proportions of undetermined diagnosis for observer 1/observer 2.

    • ↵d Interobserver agreement between observer 1 and observer 2.

    • ↵e Intermodality agreement between DSA and HR-MR.

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American Journal of Neuroradiology: 37 (12)
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Cite this article
N.J. Lee, M.S. Chung, S.C. Jung, H.S. Kim, C.-G. Choi, S.J. Kim, D.H. Lee, D.C. Suh, S.U. Kwon, D.-W. Kang, J.S. Kim
Comparison of High-Resolution MR Imaging and Digital Subtraction Angiography for the Characterization and Diagnosis of Intracranial Artery Disease
American Journal of Neuroradiology Dec 2016, 37 (12) 2245-2250; DOI: 10.3174/ajnr.A4950

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Comparison of High-Resolution MR Imaging and Digital Subtraction Angiography for the Characterization and Diagnosis of Intracranial Artery Disease
N.J. Lee, M.S. Chung, S.C. Jung, H.S. Kim, C.-G. Choi, S.J. Kim, D.H. Lee, D.C. Suh, S.U. Kwon, D.-W. Kang, J.S. Kim
American Journal of Neuroradiology Dec 2016, 37 (12) 2245-2250; DOI: 10.3174/ajnr.A4950
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