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Research ArticleNeurointervention
Open Access

Thinner Regions of Intracranial Aneurysm Wall Correlate with Regions of Higher Wall Shear Stress: A 7T MRI Study

R. Blankena, R. Kleinloog, B.H. Verweij, P. van Ooij, B. ten Haken, P.R. Luijten, G.J.E. Rinkel and J.J.M. Zwanenburg
American Journal of Neuroradiology July 2016, 37 (7) 1310-1317; DOI: https://doi.org/10.3174/ajnr.A4734
R. Blankena
aFrom the Department of Neurology and Neurosurgery (R.B., R.K., B.H.V., G.J.E.R.)
dFaculty of Science and Technology (R.B., B.t.H.), Department of Technical Medicine, University of Twente, Enschede, the Netherlands
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R. Kleinloog
aFrom the Department of Neurology and Neurosurgery (R.B., R.K., B.H.V., G.J.E.R.)
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B.H. Verweij
aFrom the Department of Neurology and Neurosurgery (R.B., R.K., B.H.V., G.J.E.R.)
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P. van Ooij
eDepartment of Biomedical Engineering and Physics (P.v.O.), Academic Medical Center, Amsterdam, the Netherlands.
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B. ten Haken
dFaculty of Science and Technology (R.B., B.t.H.), Department of Technical Medicine, University of Twente, Enschede, the Netherlands
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P.R. Luijten
bBrain Center Rudolf Magnus, Department of Radiology (P.R.L., J.J.M.Z.)
cImage Sciences Institute (P.R.L., J.J.M.Z.), University Medical Center Utrecht, Utrecht, the Netherlands
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G.J.E. Rinkel
aFrom the Department of Neurology and Neurosurgery (R.B., R.K., B.H.V., G.J.E.R.)
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J.J.M. Zwanenburg
bBrain Center Rudolf Magnus, Department of Radiology (P.R.L., J.J.M.Z.)
cImage Sciences Institute (P.R.L., J.J.M.Z.), University Medical Center Utrecht, Utrecht, the Netherlands
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REFERENCES

  1. 1.↵
    1. Nieuwkamp DJ,
    2. Setz LE,
    3. Algra A, et al
    . Changes in case fatality of aneurysmal subarachnoid haemorrhage over time, according to age, sex, and region: a meta-analysis. Lancet Neurol 2009;8:635–42 doi:10.1016/S1474-4422(09)70126-7 pmid:19501022
    CrossRefPubMedWeb of Science
  2. 2.↵
    1. Vlak MH,
    2. Algra A,
    3. Brandenburg R, et al
    . Prevalence of unruptured intracranial aneurysms, with emphasis on sex, age, comorbidity, country, and time period: a systematic review and meta-analysis. Lancet Neurol 2011;10:626–36 doi:10.1016/S1474-4422(11)70109-0 pmid:21641282
    CrossRefPubMedWeb of Science
  3. 3.↵
    1. Greving JP,
    2. Wermer MJ,
    3. Brown RD Jr., et al
    . Development of the PHASES score for prediction of risk of rupture of intracranial aneurysms: a pooled analysis of six prospective cohort studies. Lancet Neurol 2014;13:59–66 doi:10.1016/S1474-4422(13)70263-1 pmid:24290159
    CrossRefPubMed
  4. 4.↵
    1. Vlak MH,
    2. Rinkel GJ,
    3. Greebe P, et al
    . Trigger factors and their attributable risk for rupture of intracranial aneurysms: a case-crossover study. Stroke 2011;42:1878–82 doi:10.1161/STROKEAHA.110.606558 pmid:21546472
    Abstract/FREE Full Text
  5. 5.↵
    1. Wermer MJ,
    2. van der Schaaf IC,
    3. Algra A, et al
    . Risk of rupture of unruptured intracranial aneurysms in relation to patient and aneurysm characteristics: an updated meta-analysis. Stroke 2007;38:1404–10 doi:10.1161/01.STR.0000260955.51401.cd pmid:17332442
    Abstract/FREE Full Text
  6. 6.↵
    1. Meng H,
    2. Tutino V
    . High WSS or low WSS? Complex interactions of hemodynamics with intracranial aneurysm initiation, growth, and rupture: toward a unifying hypothesis. AJNR Am J Neuroradiol 2014;35:1254–62 doi:10.3174/ajnr.A3558 pmid:23598838
    Abstract/FREE Full Text
  7. 7.↵
    1. Nixon AM,
    2. Gunel M,
    3. Sumpio BE
    . The critical role of hemodynamics in the development of cerebral vascular disease. J Neurosurg 2010;112:1240–53 doi:10.3171/2009.10.JNS09759 pmid:19943737
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. Boussel L,
    2. Rayz V,
    3. Martin A, et al
    . Phase-contrast magnetic resonance imaging measurements in intracranial aneurysms in vivo of flow patterns, velocity fields, and wall shear stress: comparison with computational fluid dynamics. Magn Reson Med 2009;61:409–17 doi:10.1002/mrm.21861 pmid:19161132
    CrossRefPubMedWeb of Science
  9. 9.↵
    1. van Ooij P,
    2. Zwanenburg JJ,
    3. Visser F, et al
    . Quantification and visualization of flow in the Circle of Willis: time-resolved three-dimensional phase contrast MRI at 7 T compared with 3 T. Magn Reson Med 2013;69:868–76 doi:10.1002/mrm.24317 pmid:22618854
    CrossRefPubMed
  10. 10.↵
    1. Kleinloog R,
    2. Korkmaz E,
    3. Zwanenburg JJ, et al
    . Visualization of the aneurysm wall: a 7.0-Tesla magnetic resonance imaging study. Neurosurgery 2014;75:614–22; discussion 622 doi:10.1227/NEU.0000000000000559 pmid:25255252
    CrossRefPubMed
  11. 11.↵
    1. van der Kolk AG,
    2. Hendrikse J,
    3. Brundel M, et al
    . Multi-sequence whole-brain intracranial vessel wall imaging at 7.0 Tesla. Eur Radiol 2013;23:2996–3004 doi:10.1007/s00330-013-2905-z pmid:23736375
    CrossRefPubMed
  12. 12.↵
    1. Koning W,
    2. Rotte A de,
    3. Bluemink J, et al
    . MRI of the carotid artery at 7 Tesla: quantitative comparison with 3 Tesla. J Magn Reson Imaging 2015;41:773–80 doi:10.1002/jmri.24601 pmid:24578311
    CrossRefPubMed
  13. 13.↵
    1. Li C,
    2. Xu C,
    3. Gui C, et al
    . Level set evolution without re-initialization: a new variational formulation. In: Proceedings of the 2005 IEEE Computer Society Conference on Computer Vision and Pattern Recognition, San Diego, California. June 20–26, 2005:430–36 doi:10.1109/CVPR.2005.213
  14. 14.↵
    1. van Ooij P,
    2. Potters WV,
    3. Guédon A, et al
    . Wall shear stress estimated with phase contrast MRI in an in vitro and in vivo intracranial aneurysm. J Magn Reson Imaging 2013;38:876–84 doi:10.1002/jmri.24051 pmid:23417769
    CrossRefPubMed
  15. 15.↵
    1. Cebral JR,
    2. Castro MA,
    3. Appanaboyina S, et al
    . Efficient pipeline for image-based patient-specific analysis of cerebral aneurysm hemodynamics: technique and sensitivity. IEEE Trans Med Imaging 2005;24:457–67 doi:10.1109/TMI.2005.844159 pmid:15822804
    CrossRefPubMedWeb of Science
  16. 16.↵
    1. Mut F,
    2. Löhner R,
    3. Chien A, et al
    . Computational hemodynamics framework for the analysis of cerebral aneurysms. Int J Numer Method Biomed Eng 2011;27:822–39 doi:10.1002/cnm.1424 pmid:21643491
    CrossRefPubMed
  17. 17.↵
    1. Shojima M,
    2. Oshima M,
    3. Takagi K, et al
    . Magnitude and role of wall shear stress on cerebral aneurysm: computational fluid dynamic study of 20 middle cerebral artery aneurysms. Stroke 2004;35:2500–05 doi:10.1161/01.STR.0000144648.89172.0f pmid:15514200
    Abstract/FREE Full Text
  18. 18.↵
    1. Kadasi LM,
    2. Dent WC,
    3. Malek AM
    . Colocalization of thin-walled dome regions with low hemodynamic wall shear stress in unruptured cerebral aneurysms. J Neurosurg 2013;119:172–79 doi:10.3171/2013.2.JNS12968 pmid:23540271
    CrossRefPubMed
  19. 19.↵
    1. van Ooij P,
    2. Schneiders JJ,
    3. Marquering HA, et al
    . 3D cine phase-contrast MRI at 3T in intracranial aneurysms compared with patient-specific computational fluid dynamics. AJNR Am J Neuroradiol 2013;34:1785–91 doi:10.3174/ajnr.A3484 pmid:23598829
    Abstract/FREE Full Text
  20. 20.↵
    1. Weigel M,
    2. Hennig J
    . Diffusion sensitivity of turbo spin echo sequences. Magn Reson Med 2012;67:1528–37 doi:10.1002/mrm.24286 pmid:22532372
    CrossRefPubMed
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American Journal of Neuroradiology: 37 (7)
American Journal of Neuroradiology
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1 Jul 2016
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R. Blankena, R. Kleinloog, B.H. Verweij, P. van Ooij, B. ten Haken, P.R. Luijten, G.J.E. Rinkel, J.J.M. Zwanenburg
Thinner Regions of Intracranial Aneurysm Wall Correlate with Regions of Higher Wall Shear Stress: A 7T MRI Study
American Journal of Neuroradiology Jul 2016, 37 (7) 1310-1317; DOI: 10.3174/ajnr.A4734

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Thinner Regions of Intracranial Aneurysm Wall Correlate with Regions of Higher Wall Shear Stress: A 7T MRI Study
R. Blankena, R. Kleinloog, B.H. Verweij, P. van Ooij, B. ten Haken, P.R. Luijten, G.J.E. Rinkel, J.J.M. Zwanenburg
American Journal of Neuroradiology Jul 2016, 37 (7) 1310-1317; DOI: 10.3174/ajnr.A4734
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Cited By...

  • Quantitative analysis of unruptured intracranial aneurysm wall thickness and enhancement using 7T high resolution, black blood magnetic resonance imaging
  • High Spatiotemporal Resolution 4D Flow MRI of Intracranial Aneurysms at 7T in 10 Minutes
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  • Qualitative Assessment and Reporting Quality of Intracranial Vessel Wall MR Imaging Studies: A Systematic Review
  • Vessel wall imaging in intracranial aneurysms
  • Flow Diversion with Low-Profile Braided Stents for the Treatment of Very Small or Uncoilable Intracranial Aneurysms at or Distal to the Circle of Willis
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