Article Figures & Data
Figures
- Fig 1.
Flow chart demonstrating how patients were narrowed from a large subset to 18 patients with SAPHO syndrome and spinal involvement. *SAPHO criteria were based on Benhamou et al.14
- Fig 2.
MR imaging, CT, and bone scan of the thoracic spine in a 74-year-old woman with back pain. Sagittal T1-weighted (A) and STIR (B) images demonstrate hypo- and hyperintensity, respectively, in a curvilinear or semicircular pattern (dashed line) in contiguous vertebral body segments. Note the absence of abnormal signal within the intervertebral disc spaces. C, Sagittal CT image shows associated sclerosis (arrows) corresponding to levels of abnormal increased signal on MR imaging. D, Bone scan, posteroanterior view, demonstrates focal areas of increased radiotracer uptake within thoracic vertebral bodies and the right sternoclavicular joint (arrow). E, Previously undiagnosed plantar pustulosis was evident on physical examination.
- Fig 3.
MR images in a 32-year-old woman with back pain. Sagittal T1-weighted fat-saturated images of the thoracic spine following administration of gadolinium demonstrate multilevel enhancement (arrows) of the spinous processes (B) and bilateral facet joints (A and C).
- Fig 4.
MR images in a 69-year-old woman with cervical and thoracic back pain. A, Sagittal T2-weighted fat-suppressed image of the cervical spine demonstrates paravertebral soft-tissue thickening (arrows), extending from the C3–C4 interspace to T3. Note the abnormally high T2-weighted signal within the C5–C6 disc (arrowhead). B, Sagittal T1-weighted gadolinium-enhanced fat-suppressed image demonstrates corresponding enhancement of the paravertebral soft tissue (arrows) with disc space enhancement (arrowhead). C, Axial T1-weighted gadolinium-enhanced fat-suppressed image demonstrates enhancement of the thickened paravertebral soft tissues (arrows). D, Axial T2-weighted fat-suppressed image further demonstrates the extent of the paravertebral soft-tissue thickening (arrows).
Tables
Vertebral body findings per imaging modality
Imaging Modality Vertebral Body Finding No. of Patients MRI (n = 16) T1-weighted images (n = 16) T1 hypointensity 15 T1 hypointensity → T1 hyperintensity 1 T2-weighted images (n = 15) T2 hyperintensity 12 Mixed T2 hypo- and hyperintensity 3 Gadolinium-enhanced images (n = 9) Enhancement corresponding to areas of T1 hypointensity/T2 hyperintensity 9 CT (n = 14) Sclerosis corresponding to MR signal abnormalities 14 Technetium Tc99m methylene diphosphonate 3-phase bone scan (n = 10) Increased radiotracer uptake 10 Whole-body FDG-PET/CT (n = 2) No abnormal FDG uptake 2
