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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticleFunctional
Open Access

American Society of Functional Neuroradiology–Recommended fMRI Paradigm Algorithms for Presurgical Language Assessment

D.F. Black, B. Vachha, A. Mian, S.H. Faro, M. Maheshwari, H.I. Sair, J.R. Petrella, J.J. Pillai and K. Welker
American Journal of Neuroradiology October 2017, 38 (10) E65-E73; DOI: https://doi.org/10.3174/ajnr.A5345
D.F. Black
aFrom the Mayo Clinic (D.F.B., K.W.), Rochester Minnesota
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B. Vachha
bMemorial Sloan Kettering Cancer Center (B.V.), New York, New York
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A. Mian
cBoston University School of Medicine (A.M.), Boston, Massachusetts
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S.H. Faro
dJohns Hopkins University School of Medicine and the Johns Hopkins Hospital (S.H.F., H.I.S., J.J.P.), Baltimore, Maryland
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M. Maheshwari
eChildren's Hospital of Wisconsin (M.M.), Milwaukee, Wisconsin
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H.I. Sair
dJohns Hopkins University School of Medicine and the Johns Hopkins Hospital (S.H.F., H.I.S., J.J.P.), Baltimore, Maryland
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J.R. Petrella
fDuke University School of Medicine, (J.R.P.) Durham, North Carolina.
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J.J. Pillai
dJohns Hopkins University School of Medicine and the Johns Hopkins Hospital (S.H.F., H.I.S., J.J.P.), Baltimore, Maryland
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K. Welker
aFrom the Mayo Clinic (D.F.B., K.W.), Rochester Minnesota
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Article Figures & Data

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  • Fig 1.
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    Fig 1.

    fMRIs performed per month for language assessment at different institutions (about one-third of responders do 6+ per month).

  • Fig 2.
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    Fig 2.

    Fifty-seven percent (30/53) of responders reported being very likely to adopt language paradigm algorithms, and only 8% (4/53) reported being unlikely to adopt ASFNR recommendations.

  • Fig 3.
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    Fig 3.

    The most commonly used language paradigms were sorted into 3 tiers with the total number of imagers by using the paradigms represented on the y-axis. The first tier included SWG and Sentence Completion. The second tier included Verb Generation, Object Naming, Rhyming, and Reading Comprehension. The third tier included Antonym Generation, Semantic Decision, Noun-Verb Semantic Association, Category Naming, and other.

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    Fig 4.

    Adult algorithm for presurgical language fMRI.

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    Fig 5.

    Pediatric algorithm for presurgical language fMRI.

Tables

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  • Summary of individual task usefulness

    ParadigmAreas ActivatedPertinent Notes
    Sentence CompletionTemporal > frontalRobust overall
    Ventral language streamMay repeat
    Silent Word GenerationFrontal > temporalMore lateralizing than SC
    Middle frontal gyrusNo patient performance metric
    RhymingFrontal > temporalMore lateralizing than SC
    Middle frontal gyrus
    Object NamingFrontal > temporalMost patients can perform
    Antonym GenerationFrontal > temporalGood for pediatric patients
    Middle frontal gyrusNo patient performance metric
    Geschwind
    Passive Story ListeningTemporal > frontalEasy task for pediatrics or impaired adults
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American Journal of Neuroradiology: 38 (10)
American Journal of Neuroradiology
Vol. 38, Issue 10
1 Oct 2017
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Cite this article
D.F. Black, B. Vachha, A. Mian, S.H. Faro, M. Maheshwari, H.I. Sair, J.R. Petrella, J.J. Pillai, K. Welker
American Society of Functional Neuroradiology–Recommended fMRI Paradigm Algorithms for Presurgical Language Assessment
American Journal of Neuroradiology Oct 2017, 38 (10) E65-E73; DOI: 10.3174/ajnr.A5345

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American Society of Functional Neuroradiology–Recommended fMRI Paradigm Algorithms for Presurgical Language Assessment
D.F. Black, B. Vachha, A. Mian, S.H. Faro, M. Maheshwari, H.I. Sair, J.R. Petrella, J.J. Pillai, K. Welker
American Journal of Neuroradiology Oct 2017, 38 (10) E65-E73; DOI: 10.3174/ajnr.A5345
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