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AJNR Awards, New Junior Editors, and more. Read the latest AJNR updates

Research ArticlePediatric Neuroimaging

“Ears of the Lynx” MRI Sign Is Associated with SPG11 and SPG15 Hereditary Spastic Paraplegia

B. Pascual, S.T. de Bot, M.R. Daniels, M.C. França, C. Toro, M. Riverol, P. Hedera, M.T. Bassi, N. Bresolin, B.P. van de Warrenburg, B. Kremer, J. Nicolai, P. Charles, J. Xu, S. Singh, N.J. Patronas, S.H. Fung, M.D. Gregory and J.C. Masdeu
American Journal of Neuroradiology January 2019, 40 (1) 199-203; DOI: https://doi.org/10.3174/ajnr.A5935
B. Pascual
aFrom the Departments of Neurology (B.P., M.R.D., J.C.M.)
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S.T. de Bot
dDepartment of Neurology (S.T.d.B.), Leiden University Medical Centre, Leiden, the Netherlands
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M.R. Daniels
aFrom the Departments of Neurology (B.P., M.R.D., J.C.M.)
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M.C. França Jr
eDepartment of Neurology (M.C.F.), University of Campinas, Campinas, Brazil
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C. Toro
fNational Institutes of Health Intramural Research Program (C.T., N.J.P., M.D.G.), Bethesda, Maryland
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M. Riverol
gDepartment of Neurology (M.R.), Clínica Universidad de Navarra, Pamplona, Spain
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P. Hedera
hDepartment of Neurology (P.H.), Vanderbilt University Medical Center, Nashville, Tennessee
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M.T. Bassi
iLaboratory of Molecular Biology (M.T.B.), Scientific Institute Istituto di Ricovero e Cura a Carattere Scientifico E. Medea, Bosisio Parini, Lecco, Italy
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N. Bresolin
jDepartment of Neuroscience and Mental Health (N.B.), University Hospital Policlinico Ca'Granda, University of Milan, Milan, Italy
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B.P. van de Warrenburg
kDepartment of Neurology (B.P.v.d.W.), Donders Institute for Brain, Cognition, and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands
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B. Kremer
lDepartment of Neurology (B.K.), University Medical Center Groningen, Groningen, the Netherlands
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J. Nicolai
mDepartment of Neurology (J.N.), Maastricht University Medical Centre, Maastricht, the Netherlands
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P. Charles
nDepartment of Genetics (P.C.), Hôpital Pitié-Salpêtrière, Paris, France.
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J. Xu
bBiostatistics (J.X.)
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S. Singh
cRadiology (S.S., S.H.F.), Houston Methodist Research Institute, Houston, Texas
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N.J. Patronas
fNational Institutes of Health Intramural Research Program (C.T., N.J.P., M.D.G.), Bethesda, Maryland
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S.H. Fung
cRadiology (S.S., S.H.F.), Houston Methodist Research Institute, Houston, Texas
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M.D. Gregory
fNational Institutes of Health Intramural Research Program (C.T., N.J.P., M.D.G.), Bethesda, Maryland
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J.C. Masdeu
aFrom the Departments of Neurology (B.P., M.R.D., J.C.M.)
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American Journal of Neuroradiology: 40 (1)
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Cite this article
B. Pascual, S.T. de Bot, M.R. Daniels, M.C. França, C. Toro, M. Riverol, P. Hedera, M.T. Bassi, N. Bresolin, B.P. van de Warrenburg, B. Kremer, J. Nicolai, P. Charles, J. Xu, S. Singh, N.J. Patronas, S.H. Fung, M.D. Gregory, J.C. Masdeu
“Ears of the Lynx” MRI Sign Is Associated with SPG11 and SPG15 Hereditary Spastic Paraplegia
American Journal of Neuroradiology Jan 2019, 40 (1) 199-203; DOI: 10.3174/ajnr.A5935

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“Ears of the Lynx” MRI Sign Is Associated with SPG11 and SPG15 Hereditary Spastic Paraplegia
B. Pascual, S.T. de Bot, M.R. Daniels, M.C. França, C. Toro, M. Riverol, P. Hedera, M.T. Bassi, N. Bresolin, B.P. van de Warrenburg, B. Kremer, J. Nicolai, P. Charles, J. Xu, S. Singh, N.J. Patronas, S.H. Fung, M.D. Gregory, J.C. Masdeu
American Journal of Neuroradiology Jan 2019, 40 (1) 199-203; DOI: 10.3174/ajnr.A5935
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Cited By...

  • 'Ear of the lynx sign: hereditary spastic paraplegia (HSP) type 11
  • Clinical and neurogenetic characterisation of autosomal recessive RBL2-associated progressive neurodevelopmental disorder
  • Systematic Analysis of Brain MRI Findings in Adaptor Protein Complex 4-Associated Hereditary Spastic Paraplegia
  • 'Ears of the Lynx sign: an important and useful MRI clue for diagnosis of hereditary spastic paraplegia (HSP) caused by mutation in SPG 15 gene
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