Volumetric MRI Study of the Brain in Fetuses with Intrauterine Cytomegalovirus Infection and Its Correlation to Neurodevelopmental Outcome

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Fig 1.
Representative slices of structure boundaries; A, STV and CV. B, REBV and LEBV.
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Fig 2.
Scatterplots of volumetric measurements according to the gestational age of the CMV-infected group and the noninfected controls. Simple linear regression lines are shown for each set of data. A, STV. B, RHV. C, LHV. D, CV. E, REBV. F, LEBV.

Table 1:

Means/medians of brain volume measurements for CMV-infected and control groups^{^a}

Volume (mL)	CMV-Infected Fetuses (n = 42)	Control Fetuses (n = 50)	P
STV	184.7 (24.2)	200.9 (32.6)	.008^{^b}
RHV	93.2 (11.8)	100.2 (17.1)	.022^{^b}
LHV	92.4 (12.5)	99.5 (17.1)	.02^{^b}
CV	9.5 (1.7)	10.3 (2.2)	.084
REBV	1.58 (1.46–1.79)	1.82 (1.66–1.92)	<.001^{^b}
LEBV	1.61 (1.47–1.76)	1.79 (1.71–1.96)	<.001^{^b}

↵a STV, RHV, LHV, CV are presented as mean (SD); REBV and LEBV are presented as median (interquartile range).
↵b Significant.

Table 2:

Brain volumes of CMV-infected fetuses demonstrated as z scores^{^a}