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Index by author

May 01, 2019; Volume 40,Issue 5

  1. Panigrahi, M.

    1. FELLOWS' JOURNAL CLUBPediatrics
      Focal Cortical Dysplasia and Refractory Epilepsy: Role of Multimodality Imaging and Outcome of Surgery
      S. Jayalakshmi, S.K. Nanda, S. Vooturi, R. Vadapalli, P. Sudhakar, S. Madigubba and M. Panigrahi
      American Journal of Neuroradiology May 2019, 40 (5) 892-898; DOI: https://doi.org/10.3174/ajnr.A6041

      The authors performed a retrospective analysis of data from 188 consecutive patients with focal cortical dysplasia and refractory epilepsy with at least 2 years of postsurgery follow-up. Predictors of seizure freedom and the sensitivity of neuroimaging modalities were analyzed. MR imaging showed clear-cut FCD in 136 (72.3%) patients. Interictal FDG-PET showed focal hypo-/hypermetabolism in 144 (76.6%); in 110 patients in whom ictal SPECT was performed, focal hyperperfusion was noted in 77 (70.3%). Focal resection was the most common surgery performed in 112 (59.6%) patients. Histopathology revealed type I FCD in 102 (54.3%) patients. At last follow-up, 124 (66.0%) were seizure-free. Complete resection of FCD and type II FCD were predictors of seizure freedom. Localization of FCD on either MR imaging or PET or ictal SPECT had the highest sensitivity for seizure freedom at 97.5%. They conclude that during presurgical multimodality evaluation, localization of the extent of the epileptogenic zone in at least 2 imaging modalities helps achieve seizure freedom in about two-thirds of patients with refractory epilepsy due to FCD. FDG-PET is the most sensitive imaging modality for seizure freedom, especially in patients with type I FCD.

  2. Parsons, M.S.

    1. Adult Brain
      Image Processing to Improve Detection of Mesial Temporal Sclerosis in Adults
      F. Dahi, M.S. Parsons, H.L.P. Orlowski, A. Salter, S. Dahiya and A. Sharma
      American Journal of Neuroradiology May 2019, 40 (5) 798-801; DOI: https://doi.org/10.3174/ajnr.A6022

  3. Patel, A.

    1. Interventional
      Angiographic and Clinical Features of Noninvoluting Congenital Hemangiomas
      A. Patel, R. De Leacy and A. Berenstein
      American Journal of Neuroradiology May 2019, 40 (5) 845-848; DOI: https://doi.org/10.3174/ajnr.A6044

  4. Pedraza, S.

    1. EDITOR'S CHOICEAdult Brain
      Open Access
      Predicting Motor Outcome in Acute Intracerebral Hemorrhage
      J. Puig, G. Blasco, M. Terceño, P. Daunis-i-Estadella, G. Schlaug, M. Hernandez-Perez, V. Cuba, G. Carbó, J. Serena, M. Essig, C.R. Figley, K. Nael, C. Leiva-Salinas, S. Pedraza and Y. Silva
      American Journal of Neuroradiology May 2019, 40 (5) 769-775; DOI: https://doi.org/10.3174/ajnr.A6038

      The authors prospectively studied patients with motor deficits secondary to primary intracerebral hemorrhage within the first 12 hours of symptom onset. Patients underwent multimodal MR imaging including DTI. Intracerebral hemorrhage, perihematomal edema location and volume, and corticospinal tract involvement were assessed. The corticospinal tract was considered affected when the tractogram passed through the intracerebral hemorrhage and/or the perihematomal edema. The authors calculated affected corticospinal tract-to-unaffected corticospinal tract ratios for fractional anisotropy, mean diffusivity, and axial and radial diffusivities. Significant independent predictors of motor outcome were NIHSS and modified NIHSS at admission, posterior limb of the internal capsule involvement by intracerebral hemorrhage at admission, intracerebral hemorrhage volume at admission, 72-hour NIHSS, and 72-hour modified NIHSS. The sensitivity, specificity, and positive and negative predictive values for poor motor outcome at 3 months by a combined modified NIHSS of >6 and posterior limb of the internal capsule involvement in the first 12 hours from symptom onset were 84%, 79%, 65%, and 92%, respectively.

  5. Perez, F.A.

    1. EDITOR'S CHOICESpine
      Open Access
      Lumbar Spinal Stenosis Severity by CT or MRI Does Not Predict Response to Epidural Corticosteroid versus Lidocaine Injections
      F.A. Perez, S. Quinet, J.G. Jarvik, Q.T. Nguyen, E. Aghayev, D. Jitjai, W.D. Hwang, E.R. Jarvik, S.S. Nedeljkovic, A.L. Avins, J.M. Schwalb, F.E. Diehn, C.J. Standaert, D.R. Nerenz, T. Annaswamy, Z. Bauer, D. Haynor, P.J. Heagerty and J.L. Friedly
      American Journal of Neuroradiology May 2019, 40 (5) 908-915; DOI: https://doi.org/10.3174/ajnr.A6050

      In this secondary analysis of the CT and MR imaging studies of the prospective, double-blind Lumbar Epidural Steroid Injections for Spinal Stenosis (LESS) trial participants, the authors found no differences in baseline imaging characteristics between those receiving epidural corticosteroid and lidocaine and those receiving lidocaine alone injections. No imaging measures of spinal stenosis were associated with a differential response to corticosteroids, indicating that imaging parameters of spinal stenosis did not predict a response to epidural corticosteroids.

  6. Planel, S.

    1. Adult Brain
      Susceptibility-Weighted Angiography for the Follow-Up of Brain Arteriovenous Malformations Treated with Stereotactic Radiosurgery
      S. Finitsis, R. Anxionnat, B. Gory, S. Planel, L. Liao and S. Bracard
      American Journal of Neuroradiology May 2019, 40 (5) 792-797; DOI: https://doi.org/10.3174/ajnr.A6053

  7. Pouwels, P.J.W.

    1. Pediatrics
      Oculodentodigital Dysplasia: A Hypomyelinating Leukodystrophy with a Characteristic MRI Pattern of Brain Stem Involvement
      I. Harting, S. Karch, U. Moog, A. Seitz, P.J.W. Pouwels and N.I. Wolf
      American Journal of Neuroradiology May 2019, 40 (5) 903-907; DOI: https://doi.org/10.3174/ajnr.A6051

  8. Puig, J.

    1. EDITOR'S CHOICEAdult Brain
      Open Access
      Predicting Motor Outcome in Acute Intracerebral Hemorrhage
      J. Puig, G. Blasco, M. Terceño, P. Daunis-i-Estadella, G. Schlaug, M. Hernandez-Perez, V. Cuba, G. Carbó, J. Serena, M. Essig, C.R. Figley, K. Nael, C. Leiva-Salinas, S. Pedraza and Y. Silva
      American Journal of Neuroradiology May 2019, 40 (5) 769-775; DOI: https://doi.org/10.3174/ajnr.A6038

      The authors prospectively studied patients with motor deficits secondary to primary intracerebral hemorrhage within the first 12 hours of symptom onset. Patients underwent multimodal MR imaging including DTI. Intracerebral hemorrhage, perihematomal edema location and volume, and corticospinal tract involvement were assessed. The corticospinal tract was considered affected when the tractogram passed through the intracerebral hemorrhage and/or the perihematomal edema. The authors calculated affected corticospinal tract-to-unaffected corticospinal tract ratios for fractional anisotropy, mean diffusivity, and axial and radial diffusivities. Significant independent predictors of motor outcome were NIHSS and modified NIHSS at admission, posterior limb of the internal capsule involvement by intracerebral hemorrhage at admission, intracerebral hemorrhage volume at admission, 72-hour NIHSS, and 72-hour modified NIHSS. The sensitivity, specificity, and positive and negative predictive values for poor motor outcome at 3 months by a combined modified NIHSS of >6 and posterior limb of the internal capsule involvement in the first 12 hours from symptom onset were 84%, 79%, 65%, and 92%, respectively.

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