Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticlePediatrics

Neuroimaging Findings in Moebius Sequence

D.A. Herrera, N.O. Ruge, M.M. Florez, S.A. Vargas, M. Ochoa-Escudero and M. Castillo
American Journal of Neuroradiology May 2019, 40 (5) 862-865; DOI: https://doi.org/10.3174/ajnr.A6028
D.A. Herrera
aFrom the Department of Radiology (D.A.H., M.M.F., S.A.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for D.A. Herrera
N.O. Ruge
bGrupo de Neurociencias (N.O.R.), Universidad de Antioquia, Medellín, Colombia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for N.O. Ruge
M.M. Florez
aFrom the Department of Radiology (D.A.H., M.M.F., S.A.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M.M. Florez
S.A. Vargas
aFrom the Department of Radiology (D.A.H., M.M.F., S.A.V.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for S.A. Vargas
M. Ochoa-Escudero
cDepartment of Radiology (M.O.-E.), Hospital Pablo Tobón Uribe, Medellín, Colombia
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M. Ochoa-Escudero
M. Castillo
dDepartment of Radiology (M.C.), University of North Carolina, Chapel Hill, North Carolina.
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for M. Castillo
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

REFERENCES

  1. 1.↵
    1. Abramson DL,
    2. Cohen MM Jr.,
    3. Mulliken JB
    . Mobius syndrome: classification and grading system. Plast Reconstr Surg 1998;102:961–67 doi:10.1097/00006534-199809020-00004 pmid:9734409
    CrossRefPubMed
  2. 2.↵
    1. Picciolini O,
    2. Porro M,
    3. Cattaneo E, et al
    . Moebius syndrome: clinical features, diagnosis, management and early intervention. Ital J Pediatr 2016;42:56 doi:10.1186/s13052-016-0256-5 pmid:27260152
    CrossRefPubMed
  3. 3.↵
    1. Ouanounou S,
    2. Saigal G,
    3. Birchansky S
    . Möbius syndrome. AJNR Am J Neuroradiol 2005;26:430–32 pmid:15709151
    Abstract/FREE Full Text
  4. 4.↵
    1. Budić I,
    2. Šurdilović D,
    3. Slavković A, et al
    . Moebius syndrome: challenges of airway management. Acta Clin Croat 2016;55(Suppl 1):94–97 pmid:27276780
    PubMed
  5. 5.↵
    1. Jissendi-Tchofo P,
    2. Severino M,
    3. Nguema-Edzang B, et al
    . Update on neuroimaging phenotypes of mid-hindbrain malformations. Neuroradiology 2015;57:113–38 doi:10.1007/s00234-014-1431-2 pmid:25339235
    CrossRefPubMed
  6. 6.↵
    1. Pedersen LK,
    2. Maimburg RD,
    3. Hertz JM, et al
    . Moebius sequence: a multidisciplinary clinical approach. Orphanet J Rare Dis 2017;12:4 doi:10.1186/s13023-016-0559-z pmid:28061881
    CrossRefPubMed
  7. 7.↵
    1. St Charles S,
    2. DiMario FJ Jr.,
    3. Grunnet ML
    . Möbius sequence: further in vivo support for the subclavian artery supply disruption sequence. Am J Med Genet 1993;47:289–93 doi:10.1002/ajmg.1320470230 pmid:8213922
    CrossRefPubMedWeb of Science
  8. 8.↵
    1. Adam MP,
    2. Ardinger HH,
    3. Pagon RA, et al.
    1. Whitman M,
    2. Hunter DG,
    3. Engle EC
    . Congenital fibrosis of the extraocular muscles. In: Adam MP, Ardinger HH, Pagon RA, et al., eds. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2019
  9. 9.↵
    1. McKay VH,
    2. Touil LL,
    3. Jenkins D, et al
    . Managing the child with a diagnosis of Moebius syndrome: more than meets the eye. Arch Dis Child 2016;101:843–46 doi:10.1136/archdischild-2015-310043 pmid:26868039
    Abstract/FREE Full Text
  10. 10.↵
    1. Fons-Estupiñá MC,
    2. Póo P,
    3. Colomer J, et al
    . Moebius sequence: clinico-radiological findings [in Spanish]. Rev Neurol 2007;44:583–88 pmid:17523115
    PubMed
  11. 11.↵
    1. Pedraza S,
    2. Gámez J,
    3. Rovira A, et al
    . MRI findings in Möbius syndrome: correlation with clinical features. Neurology 2000;55:1058–60 doi:10.1212/WNL.55.7.1058 pmid:11061273
    Abstract/FREE Full Text
  12. 12.↵
    1. Lengyel D,
    2. Zaunbauer W,
    3. Keller E, et al
    . Möbius syndrome: MRI findings in three cases. J Pediatr Ophthalmol Strabismus 2000;37:305–08 pmid:11020114
    PubMed
  13. 13.↵
    1. Verzijl HT,
    2. Valk J,
    3. De Vries R, et al
    . Radiologic evidence for absence of the facial nerve in Möbius syndrome. Neurology 2005;64:849–55 doi:10.1212/01.WNL.0000152980.92436.D9 pmid:15753421
    Abstract/FREE Full Text
  14. 14.↵
    1. Marques-Dias MJ,
    2. Gonzalez CH,
    3. Rosemberg S
    . Möbius sequence in children exposed in utero to misoprostol: neuropathological study of three cases. Birth Defects Res A Clin Mol Teratol 2003;67:1002–07 doi:10.1002/bdra.10144 pmid:14745923
    CrossRefPubMed
  15. 15.↵
    1. Sarnat HB
    . Watershed infarcts in the fetal and neonatal brainstem: an aetiology of central hypoventilation, dysphagia, Möbius syndrome and micrognathia. Eur J Paediatr Neurol 2004;8:71–87 doi:10.1016/j.ejpn.2003.12.005 pmid:15253055
    CrossRefPubMed
  16. 16.↵
    1. Pirmez R,
    2. Freitas ME,
    3. Gasparetto EL, et al
    . Moebius syndrome and holoprosencephaly following exposure to misoprostol. Pediatr Neurol 2010;43:371–73 doi:10.1016/j.pediatrneurol.2010.05.026 pmid:20933185
    CrossRefPubMed
  17. 17.↵
    1. Matsui K,
    2. Kataoka A,
    3. Yamamoto A, et al
    . Clinical characteristics and outcomes of Möbius syndrome in a children's hospital. Pediatr Neurol 2014;51:781–89 doi:10.1016/j.pediatrneurol.2014.08.011 pmid:25306435
    CrossRefPubMed
  18. 18.↵
    1. Osborn AG,
    2. Preece MT
    . Intracranial cysts: radiologic-pathologic correlation and imaging approach. Radiology 2006;239:650–64 doi:10.1148/radiol.2393050823 pmid:16714456
    CrossRefPubMedWeb of Science
  19. 19.↵
    1. Conde Sardón R
    . Arachnoid cysts: historical evolution of the concept and pathophysiological theories [in Spanish]. Neurocirugia (Astur) 2015;26:192–95 doi:10.1016/j.neucir.2015.03.001 pmid:25887058
    CrossRefPubMed
  20. 20.↵
    1. Leventer RJ,
    2. Guerrini R,
    3. Dobyns WB
    . Malformations of cortical development and epilepsy. Dialogues Clin Neurosci 2008;10:47–62 pmid:18472484
    PubMed
  21. 21.↵
    1. Gutowski NJ,
    2. Chilton JK
    . The congenital cranial dysinnervation disorders. Arch Dis Child 2015;100:678–81 doi:10.1136/archdischild-2014-307035 pmid:25633065
    Abstract/FREE Full Text
  22. 22.↵
    1. Bahi-Buisson N,
    2. Poirier K,
    3. Fourniol F, et al
    . The wide spectrum of tubulinopathies: what are the key features for the diagnosis? Brain 2014;137:1676–700 doi:10.1093/brain/awu082 pmid:24860126
    CrossRefPubMed
  23. 23.↵
    1. Barth PG,
    2. Majoie CB,
    3. Caan MW, et al
    . Pontine tegmental cap dysplasia: a novel brain malformation with a defect in axonal guidance. Brain 2007;130:2258–66 doi:10.1093/brain/awm188 pmid:17690130
    CrossRefPubMedWeb of Science
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 40 (5)
American Journal of Neuroradiology
Vol. 40, Issue 5
1 May 2019
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Neuroimaging Findings in Moebius Sequence
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
D.A. Herrera, N.O. Ruge, M.M. Florez, S.A. Vargas, M. Ochoa-Escudero, M. Castillo
Neuroimaging Findings in Moebius Sequence
American Journal of Neuroradiology May 2019, 40 (5) 862-865; DOI: 10.3174/ajnr.A6028

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Neuroimaging Findings in Moebius Sequence
D.A. Herrera, N.O. Ruge, M.M. Florez, S.A. Vargas, M. Ochoa-Escudero, M. Castillo
American Journal of Neuroradiology May 2019, 40 (5) 862-865; DOI: 10.3174/ajnr.A6028
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • Materials and Methods
    • Results
    • Discussion
    • Conclusions
    • REFERENCES
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref (18)
  • Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

  • Imaging of congenital cranial dysinnervation disorders: What radiologist wants to know?
    Ahmed Abdel Khalek Abdel Razek, Hala Maher, Manal Ali Kasem, Eman Helmy
    Clinical Imaging 2021 71
  • Imaging Anatomy and Pathology of the Intracranial and Intratemporal Facial Nerve
    Burce Ozgen Mocan
    Neuroimaging Clinics of North America 2021 31 4
  • Neuroimaging in Children with Ophthalmological Complaints: A Review
    Mika Shapira Rootman, Gad Dotan, Osnat Konen
    Journal of Neuroimaging 2021 31 3
  • Prenatal diagnosis of Poland-Möbius syndrome by multimodality fetal imaging
    Granlee V. Nguyen, Luis F. Goncalves, Jennifer Vaughn, Neil Friedman, Jessica Wickland, Patricia Cornejo
    Pediatric Radiology 2023 53 10
  • Towards an understanding of the aetiology, genomic landscape and management of Moebius syndrome
    Ekaterina Lyulcheva-Bennett, Wendy Blumenow, Adelene O’Connor, Maria Kelly, Daimark Bennett, Adel Fattah
    Journal of Translational Genetics and Genomics 2023 7 4
  • Neurogenic bladder as a lurking complication in Moebius syndrome
    Yuichiro Tanaka, Takanobu Maekawa, Rumiko Eura, Yuichi Hasegawa, Mitsuru Kubota
    Brain and Development 2022 44 1
  • Poland–Mebius syndrome: A clinical case and review of the literature
    Alina М. Khodorovskaya, Olga E. Agranovich, Margarita V. Savina, Yuriy E. Garkavenko, Denis Yu. Grankin, Evgenii V. Melchenko, Bagauddin H. Dolgiev, Sergey А. Braylov, Elena V. Kanorskaya, Victoria V. Morozova
    Pediatric Traumatology, Orthopaedics and Reconstructive Surgery 2024 12 1
  • The different shapes of the fourth ventricle
    C.W. Yap, C. Yong, B.K.H. Soon
    Clinical Radiology 2023 78 12
  • A rare cause of arterial hypertension in a child with developmental delay: Answers
    Cemile Pehlivanoglu, Hulya Maras Genc, Sevinc Kalın
    Pediatric Nephrology 2022 37 2
  • Beyond the Eyes: Clinico-Radiological Correlation of Bilateral Complete Horizontal Gaze Palsy in Moebius Syndrome
    Alamelu Alagappan, Biswamohan Mishra, Biswajit Sahoo, Suprava Naik, Manoj K Nayak
    Cureus 2024

More in this TOC Section

  • Comparison of Image Quality and Radiation Dose in Pediatric Temporal Bone CT Using Photon-Counting Detector CT and Energy-Integrating Detector CT
  • SyMRI & MR Fingerprinting in Brainstem Myelination
  • Gad Contrast in PEDS Seizure Evaluation
Show more Pediatrics

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire