Article Figures & Data
Figures
- Fig 1.
Diffusion images and metrics. A, Patient's sagittal T2-weighted image with overlay shows where 2 different diffusion imaging volumes (A1 and A2) were acquired and to which region they were assigned. B, Sample DTI-derived maps for each region for the same patients as in A. B0 indicates minimally weighted diffusion image; CV, cervical; UT, upper thoracic; TL, thoracolumbar; CN, conus. Scale bars show the range of visualized values for each metric.
- Fig 2.
Average regional DTI indices as a function of age. Age-related trends are shown across pediatric development for each spinal cord region and diffusion-derived index. Circles show mean DTI-derived index values for individual patients, solid lines indicate the age-related trend, and dashed lines indicate the 95% confidence interval.
Tables
ANCOVA and eta statistics
ANCOVA/Factor Sum Squared df Mean Squared F P Value η2 Partial η2 Axial diffusivity Main effects Age 3.045 1 3.045 44.26 <.001 0.1169 0.1271 Region 1.801 3 0.600 8.72 <.001 0.0692 0.0793 Interaction Age × region 0.280 3 0.093 1.36 .26 0.0108 0.0132 Model error 20.917 304 0.069 0.8032 Model totals 26.044 Radial diffusivity Main effects Age 0.014 1 0.014 2.24 .14 0.0069 0.0073 Region 0.101 3 0.034 5.43 .001 0.0501 0.0508 Interaction Age × region 0.018 3 0.006 0.94 .42 0.0087 0.0092 Model error 1.890 304 0.006 0.9344 Model totals 2.023 Mean diffusivity Main effects Age 0.270 1 0.270 16.20 <.001 0.0469 0.0506 Region 0.346 3 0.115 6.93 <.001 0.0602 0.0640 Interaction Age × region 0.072 3 0.024 1.44 .23 0.0125 0.0140 Model error 5.061 304 0.017 0.8804 Model totals 5.749 Fractional anisotropy Main effects Age 0.563 1 0.563 96.11 <.001 0.2258 0.2402 Region 0.115 3 0.038 6.55 <.001 0.0462 0.0607 Interaction Age × region 0.034 3 0.011 1.94 .12 0.0136 0.0187 Model error 1.781 304 0.006 0.7143 Model totals 2.493
