Article Figures & Data
Figures
- FIG 1.
Flow diagram depicting the literature review, search strategy, and selection process using the PRISMA guidelines.
- FIG 2.
Topography and outcome brain map generated using the β-coefficients from pooled ORs for each region based on the random-effects model, indicating the relative weight of each ASPECTS region to M6, which was determined to be the region with greatest significant association with poor outcomes. The ASPECTS region most strongly associated with poor neurologic outcome was assigned a value of 1.0, and the remaining regions were assigned values relative to the maxima and according to their respective β-coefficients. Reprinted with permission from Barber et al.34 C indicates caudate nucleus; L, lentiform nucleus; IC, internal capsule; I, insula.
- FIG 3.
Forest plots demonstrating the contribution of individual ASPECTS regions, with 90-day functional outcome based on collective data of the 9 included studies.
- FIG 4.
Topography and outcome brain map generated using the β-coefficients from pooled ORs for each region based on NCCT ASPECTS studies. Note that data shown are calculated from both hemispheres but are displayed unilaterally for clarity. The ASPECTS region most strongly associated with poor neurologic outcome was assigned a value of 1.0, and the remaining regions were assigned values relative to the maxima and according to their respective β-coefficients. Reprinted with permission from Barber et al.34 C indicates caudate nucleus; L, lentiform nucleus; IC, internal capsule; I, insula.
- FIG 5.
Topography and outcome brain map generated using the β-coefficients from pooled ORs for each region based on DWI ASPECTS studies. Note that data shown are calculated from both hemispheres but are displayed unilaterally for clarity. The ASPECTS region most strongly associated with poor neurologic outcome was assigned a value of 1.0, and the remaining regions were assigned values relative to the maxima and according to their respective β-coefficients. Reprinted with permission from Barber et al.34 C indicates caudate nucleus; L, lentiform nucleus; IC, internal capsule; I, insula.
- FIG 6.
Topography and outcome brain map generated using the β-coefficients from pooled ORs for each region based on the laterality of the stroke. The ASPECTS region most strongly associated with poor neurologic outcome was assigned a value of 1.0, and the remaining regions were assigned values relative to the maxima and according to their respective β-coefficients. Reprinted with permission from Barber et al.34 C indicates caudate nucleus; L, lentiform nucleus; IC, internal capsule; I, insula.
Tables
I2 Statistics and the Egger weighted regression statistics
Region I2 I2 Interpretation Egger Intercept Interpretation M1 0.00% Low heterogeneity 0.308 (P = .372) Publication bias not significant M2 19.56% Low heterogeneity 0.532 (P = .309) Publication bias not significant M3 32.84% Moderate heterogeneity –0.026 (P = .491) Publication bias not significant M4 11.44% Low heterogeneity –0.207 (P = .414) Publication bias not significant M5 2.85% Low heterogeneity 0.211 (P = .373) Publication bias not significant M6 18.21% Low heterogeneity –0.066 (P = .468) Publication bias not significant C 17.36% Low heterogeneity –1.290 (P = .085) Publication bias not significant IC 5.89% Low heterogeneity –1.372 (P = .031) Significant publication bias L 14.91% Low heterogeneity –1.406 (P = .018) Significant publication bias I 40.55% Moderate heterogeneity –1.670 (P = .023) Significant publication bias Note:—C indicates caudate; IC, internal capsule; L, lentiform; I, insula.
