Prediction of Outcome Using Quantified Blood Volume in Aneurysmal SAH

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Fig 1.
Calibration plots of the TBV model for poor outcome (A), the TBV model for death (B), the location-specific model for poor outcome (C), the location-specific model for death (D), the modified Fisher model for poor outcome (E), and the modified Fisher model for death (F).

Table 1:

Characteristics of the development and validation cohorts^{^a}

	Development (n = 409)	Validation (n = 317)	P Value
Age (mean) (SD) (yr)	57 (13)	59 (14)	.05
Female sex	277 (68)	222 (70)	.5
History of hypertension	131 (35)	96 (31)	.2
History of cardiovascular disease	75 (20)	61 (20)	1
History of diabetes	25 (7)	18 (6)	.6
WFNS score			.04
I	182 (46)	106 (39)
II	51 (13)	37 (14)
III	12 (3)	9 (3)
IV	68 (17)	40 (15)
V	81 (21)	74 (27)
Aneurysm location			.44
Anterior circulation	324 (79)	243 (82)
Posterior circulation	85 (21)	54 (18)
Aneurysm size (median) (IQR) (mm)	6 (4–9)	5 (4–8)	.96
Aneurysm treatment			<.001
Coiling	273 (67)	153 (48)
Clipping	64 (16)	95 (30)
No treatment	72 (18)	69 (22)
Total blood volume (median) (IQR) (mL)	29 (12–60)	26 (9–51)	.36
Cisternal blood volume (median) (IQR) (mL)	20 (8–41)	18 (6–34)	.1
Intraventricular blood volume (median) (IQR) (mL)	0.5 (0–2)	0.3 (0–2)	.1
Intraparenchymal blood volume (median) (IQR) (mL)	0 (0–3)	0 (0–3)	.8
Modified Fisher grade			.15
0	20 (5)	12 (4)
1	26 (6)	9 (3)
2	7 (2)	8(3)
3	92 (23)	83 (27)
4	262 (64)	201 (64)
Clinical DCI	109 (27)	61 (29)	.6

Table 2:

Model validation