Involvement of the Spinal Cord in Primary Mitochondrial Disorders: A Neuroimaging Mimicker of Inflammation and Ischemia in Children

C.A.P.F. Alves; A. Goldstein; S.R. Teixeira; J.S. Martin-Saavedra; I.P. de Barcelos; G. Fadda; L. Caschera; M. Kidd; F.G. Gonçalves; E.M. McCormick; M.J. Falk; Z. Zolkipli-Cunningham; A. Vossough; G. Zuccoli

doi:10.3174/ajnr.A6910

Research ArticlePediatrics

Open Access

Involvement of the Spinal Cord in Primary Mitochondrial Disorders: A Neuroimaging Mimicker of Inflammation and Ischemia in Children

C.A.P.F. Alves, A. Goldstein, S.R. Teixeira, J.S. Martin-Saavedra, I.P. de Barcelos, G. Fadda, L. Caschera, M. Kidd, F.G. Gonçalves, E.M. McCormick, M.J. Falk, Z. Zolkipli-Cunningham, A. Vossough and G. Zuccoli

American Journal of Neuroradiology February 2021, 42 (2) 389-396; DOI: https://doi.org/10.3174/ajnr.A6910

C.A.P.F. Alves

aFrom the Division of Neuroradiology, Department of Radiology (C.A.P.F.A., S.R.T., J.S.M.S., L.C., F.G.G., A.V., G.Z.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for C.A.P.F. Alves

A. Goldstein

bDivision of Human Genetics, Department of Pediatrics (A.G., E.M.M., M.J.F., Z.Z.-C.), Mitochondrial Medicine Frontier Program

ePediatrics (A.G., M.J.F., Z.Z.-C.) University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for A. Goldstein

S.R. Teixeira

aFrom the Division of Neuroradiology, Department of Radiology (C.A.P.F.A., S.R.T., J.S.M.S., L.C., F.G.G., A.V., G.Z.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for S.R. Teixeira

J.S. Martin-Saavedra

aFrom the Division of Neuroradiology, Department of Radiology (C.A.P.F.A., S.R.T., J.S.M.S., L.C., F.G.G., A.V., G.Z.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for J.S. Martin-Saavedra

I.P. de Barcelos

cDivision of Human Genetics (I. P.d.B.), Department of Pediatrics, Center for Applied Genomics, Children’s Hospital of Philadelphia, Philadelphia, Pennsylvania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for I.P. de Barcelos

G. Fadda

dDepartments of Neurology (G.F.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for G. Fadda

L. Caschera

aFrom the Division of Neuroradiology, Department of Radiology (C.A.P.F.A., S.R.T., J.S.M.S., L.C., F.G.G., A.V., G.Z.)

hNeuroradiology Unit (L.C.), Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Via Francesco Sforza 35, Milan, Italy

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for L. Caschera

M. Kidd

fCentre for Statistical Consultation (M.K.), University of Stellenbosch, South Africa

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for M. Kidd

F.G. Gonçalves

aFrom the Division of Neuroradiology, Department of Radiology (C.A.P.F.A., S.R.T., J.S.M.S., L.C., F.G.G., A.V., G.Z.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for F.G. Gonçalves

E.M. McCormick

bDivision of Human Genetics, Department of Pediatrics (A.G., E.M.M., M.J.F., Z.Z.-C.), Mitochondrial Medicine Frontier Program

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for E.M. McCormick

M.J. Falk

bDivision of Human Genetics, Department of Pediatrics (A.G., E.M.M., M.J.F., Z.Z.-C.), Mitochondrial Medicine Frontier Program

ePediatrics (A.G., M.J.F., Z.Z.-C.) University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for M.J. Falk

Z. Zolkipli-Cunningham

bDivision of Human Genetics, Department of Pediatrics (A.G., E.M.M., M.J.F., Z.Z.-C.), Mitochondrial Medicine Frontier Program

ePediatrics (A.G., M.J.F., Z.Z.-C.) University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for Z. Zolkipli-Cunningham

A. Vossough

aFrom the Division of Neuroradiology, Department of Radiology (C.A.P.F.A., S.R.T., J.S.M.S., L.C., F.G.G., A.V., G.Z.)

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for A. Vossough

G. Zuccoli

aFrom the Division of Neuroradiology, Department of Radiology (C.A.P.F.A., S.R.T., J.S.M.S., L.C., F.G.G., A.V., G.Z.)

gThe Program for the Study of Neurodevelopment in Rare Disorders (G.Z.), Children’s Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania.

Find this author on Google Scholar
Find this author on PubMed
Search for this author on this site
ORCID record for G. Zuccoli

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

Submit a Response to This Article

Compose eLetter

Title *

Contents

More information about text formats

Plain text

No HTML tags allowed.
Web page addresses and e-mail addresses turn into links automatically.
Lines and paragraphs break automatically.

Author Information

Contributors
First Name and Middle Initial * First or given name, e.g. 'Peter'. Last Name * Your last, or family, name, e.g. 'MacMoody'. Email Address * Your email address, e.g. higgs-boson@gmail.com Occupation * Your role and/or occupation, e.g. 'Orthopedic Surgeon'. Affiliation * Your organization or institution (if applicable), e.g. 'Royal Free Hospital'.

Statement of Competing Interests

Competing interests? *

Yes

Please describe the competing interests

Vertical Tabs

Jump to comment:

No eLetters have been published for this article.

PreviousNext

In this issue

American Journal of Neuroradiology

Vol. 42, Issue 2

1 Feb 2021

Table of Contents
Index by author
Complete Issue (PDF)

Download PDF

Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Your Email *

Your Name *

Send To *

Enter multiple addresses on separate lines or separate them with commas.

You are going to email the following Involvement of the Spinal Cord in Primary Mitochondrial Disorders: A Neuroimaging Mimicker of Inflammation and Ischemia in Children

Message Subject (Your Name) has sent you a message from American Journal of Neuroradiology

Message Body (Your Name) thought you would like to see the American Journal of Neuroradiology web site.

Your Personal Message

CAPTCHA

This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

Cite this article

Involvement of the Spinal Cord in Primary Mitochondrial Disorders: A Neuroimaging Mimicker of Inflammation and Ischemia in Children

American Journal of Neuroradiology Feb 2021, 42 (2) 389-396; DOI: 10.3174/ajnr.A6910

Citation Manager Formats

BibTeX
Bookends
EasyBib
EndNote (tagged)
EndNote 8 (xml)
Medlars
Mendeley
Papers
RefWorks Tagged
Ref Manager
RIS
Zotero

0 Responses

Respond to this article

Bookmark this article

User Name *

Password *

Remember my user name & password.

Involvement of the Spinal Cord in Primary Mitochondrial Disorders: A Neuroimaging Mimicker of Inflammation and Ischemia in Children

American Journal of Neuroradiology Feb 2021, 42 (2) 389-396; DOI: 10.3174/ajnr.A6910

Share This Article:

Tweet Widget
Facebook Like
Google Plus One

Purchase

Jump to section

Article
Figures & Data
Supplemental
Info & Metrics
Responses
References
PDF

PubMed
Google Scholar

Cited By...

Single Large-Scale Mitochondrial Deletion Syndromes: Neuroimaging Phenotypes and Longitudinal Progression in Pediatric Patients
Teaching NeuroImage: Leber Hereditary Optic Neuropathy With Longitudinal Spinal Cord Lesion Mimicking Spinal Cord Infarction

Crossref (10)
Google Scholar

This article has been cited by the following articles in journals that are participating in Crossref Cited-by Linking.

Advancing the neuroimaging diagnosis and understanding of mitochondrial disorders

César Augusto P.F. Alves, Matthew T. Whitehead

Neurotherapeutics 2024 21 1
Arterioectatic Spinal Angiopathy of Childhood: Clinical, Imaging, Laboratory, Histologic, and Genetic Description of a Novel CNS Vascular Pathology

T. Abruzzo, R. van den Berg, S. Vadivelu, S.W. Hetts, M. Dishop, P. Cornejo, V. Narayanan, K.E. Ramsey, C. Coopwood, E.G. Medici-van den Herik, S.D. Roosendaal, M. Lawton, S. Bernes

American Journal of Neuroradiology 2022 43 7
Leigh syndrome mimicking neuromyelitis optica spectrum disorder (NMOSD)

Nee Na Kim, Omar Abdel-Mannan, James Davidson, Pascale Du Pre, Rachel Kneen, Kshitij Mankad, Yael Hacohen

Multiple Sclerosis Journal 2023 29 7
Nelarabine-induced myelopathy in patients undergoing allogeneic hematopoietic cell transplantation: a report of three cases

Takanori Fukuta, Takashi Tanaka, Taiki Hashimoto, Kenji Isahaya, Yuko Kubo, Yoshihisa Yamano, Kaishi Satomi, Nobuyoshi Hiraoka, Nami Shirakawa, Ayumu Arakawa, Chitose Ogawa, Nao Nishimura, Jun Aoki, Ayumu Ito, Yoshihiro Inamoto, Sung-Won Kim, Takahiro Fukuda

International Journal of Hematology 2023 117 6
Teaching NeuroImage: Leber Hereditary Optic Neuropathy With Longitudinal Spinal Cord Lesion Mimicking Spinal Cord Infarction

Bing Zhao, Yuan Sun, Yong Qing Zhang, Chuanzhu Yan

Neurology 2022 98 11
Overview of neuroimaging in primary mitochondrial disorders

Sedat Giray Kandemirli, Khalid Al-Dasuqi, Bulent Aslan, Amy Goldstein, Cesar Augusto P. F. Alves

Pediatric Radiology 2025 55 4
Single Large-Scale Mitochondrial Deletion Syndromes: Neuroimaging Phenotypes and Longitudinal Progression in Pediatric Patients

Cesar A.P.F. Alves, Maria Camilla Rossi-Espagnet, Francisco Perez, Amirreza Manteghinejad, James T. Peterson, Rebecca Ganetzky, Antonio Napolitano, Francesco Grassi, Ibrahim George-Sankoh, Harun Yildiz, Colleen Muraresku, Marni J. Falk, Diego Martinelli, Daniela Longo, Adeline Vanderver, Carlo Gandolfo, Russell P. Saneto, Amy Goldstein, Arastoo Vossough

American Journal of Neuroradiology 2025
A New Perspective On Arterioectatic Spinal Angiopathy with a Reversible Pattern: Cause or Consequence?

Civan Islak, Ömer Bağcılar, Hakan Hatem Selçuk, Sema Saltık, Bora Korkmazer, Tanyel Zubarioğlu, Serdar Arslan, Ahmet Üstündag, Osman Kızılkılıç

Clinical Neuroradiology 2025 35 1
Spectrum of clinical neuroimaging in mitochondrial disorders: a neuroanatomical approach

Kate Kielty, John Collyer, Krrithvi Dharini Ganesh, Srikala Narayanan, Deepa S. Rajan

Pediatric Radiology 2025
Spinal Cord Involvement in Adult Mitochondrial Diseases: A Cohort Study

Guido Primiano, Paolo Mariotti, Ida Turrini, Cristina Sancricca, Andrea Sabino, Alessandra Torraco, Rosalba Carrozzo, Serenella Servidei

Life 2021 12 1

Main menu

User menu

Search

American Journal of Neuroradiology

Involvement of the Spinal Cord in Primary Mitochondrial Disorders: A Neuroimaging Mimicker of Inflammation and Ischemia in Children

Plain text

Vertical Tabs

Jump to comment:

In this issue

Citation Manager Formats

Related Articles

Cited By...

More in this TOC Section

Similar Articles

Indexed Content

Cases

Special Collections

Resources

Multimedia

About Us

American Society of Neuroradiology