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Research ArticleNeuroimaging Physics/Functional Neuroimaging/CT and MRI Technology

Functional Connectivity Changes on Resting-State fMRI after Mild Traumatic Brain Injury: A Systematic Review

Siddhant Dogra, Soroush Arabshahi, Jason Wei, Lucia Saidenberg, Stella K. Kang, Sohae Chung, Andrew Laine and Yvonne W. Lui
American Journal of Neuroradiology June 2024, 45 (6) 795-801; DOI: https://doi.org/10.3174/ajnr.A8204
Siddhant Dogra
aFrom the Department of Radiology (S.D., J.W., S.K.K., S.C., Y.L.), New York University Grossman School of Medicine, New York, New York
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Soroush Arabshahi
bDepartment of Biomedical Engineering (S.A., A.L.), Department of Radiology, Columbia University, New York, New York
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Jason Wei
aFrom the Department of Radiology (S.D., J.W., S.K.K., S.C., Y.L.), New York University Grossman School of Medicine, New York, New York
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Lucia Saidenberg
cDepartment of Neurology (L.S.), Department of Radiology. New York University Grossman School of Medicine, New York, New York
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Stella K. Kang
aFrom the Department of Radiology (S.D., J.W., S.K.K., S.C., Y.L.), New York University Grossman School of Medicine, New York, New York
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Sohae Chung
aFrom the Department of Radiology (S.D., J.W., S.K.K., S.C., Y.L.), New York University Grossman School of Medicine, New York, New York
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Andrew Laine
bDepartment of Biomedical Engineering (S.A., A.L.), Department of Radiology, Columbia University, New York, New York
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Yvonne W. Lui
aFrom the Department of Radiology (S.D., J.W., S.K.K., S.C., Y.L.), New York University Grossman School of Medicine, New York, New York
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    FIG 1.

    PRISMA flow diagram detailing study identification, screening, and inclusion.

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    FIG 2.

    FC changes, categorized on an ordinal scale and separated by the time since injury. −2 = only decreased FC changes, −1 = more areas of decreased FC change than areas of increased FC change, 0 = no FC changes (black) or the same number of areas of decreased and increased FC (gray), 1 = more areas of increased FC change, 2 = only areas of increased FC changes (changes all relative to results in healthy controls). Gray bars are separate from black bars, ie, 3 studies found an equal number of areas of increased and decreased FC in the DMN at <1 month. Eight found no changes, so a total of 11 studies were classified as a 0.

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American Journal of Neuroradiology: 45 (6)
American Journal of Neuroradiology
Vol. 45, Issue 6
1 Jun 2024
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Siddhant Dogra, Soroush Arabshahi, Jason Wei, Lucia Saidenberg, Stella K. Kang, Sohae Chung, Andrew Laine, Yvonne W. Lui
Functional Connectivity Changes on Resting-State fMRI after Mild Traumatic Brain Injury: A Systematic Review
American Journal of Neuroradiology Jun 2024, 45 (6) 795-801; DOI: 10.3174/ajnr.A8204

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fMRI Connectivity Changes After Mild Brain Injury
Siddhant Dogra, Soroush Arabshahi, Jason Wei, Lucia Saidenberg, Stella K. Kang, Sohae Chung, Andrew Laine, Yvonne W. Lui
American Journal of Neuroradiology Jun 2024, 45 (6) 795-801; DOI: 10.3174/ajnr.A8204
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