Functional Connectivity Changes on Resting-State fMRI after Mild Traumatic Brain Injury: A Systematic Review

References

1. 1.↵
   1. McDonald BC,
   2. Saykin AJ,
   3. McAllister TW

   . Functional MRI of mild traumatic brain injury (mTBI): progress and perspectives from the first decade of studies. Brain Imaging Behav 2012;6:193–207 doi:10.1007/s11682-012-9173-4 pmid:22618832

   CrossRefPubMedWeb of Science
2. 2.↵
   1. Stevens MC,
   2. Lovejoy D,
   3. Kim J, et al

   . Multiple resting state network functional connectivity abnormalities in mild traumatic brain injury. Brain Imaging Behav 2012;6:293–318 doi:10.1007/s11682-012-9157-4 pmid:22555821

   CrossRefPubMed
3. 3.↵
   1. Biswal B,
   2. Yetkin FZ,
   3. Haughton VM, et al

   . Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 1995;34:537–41 doi:10.1002/mrm.1910340409 pmid:8524021

   CrossRefPubMedWeb of Science
4. 4.↵
   1. Mayer AR,
   2. Mannell MV,
   3. Ling J, et al

   . Functional connectivity in mild traumatic brain injury. Hum Brain Mapp 2011;32:1825–35 doi:10.1002/hbm.21151 pmid:21259381

   CrossRefPubMedWeb of Science
5. 5.↵
   1. Seewoo BJ,
   2. Joos AC,
   3. Feindel KW

   . An analytical workflow for seed-based correlation and independent component analysis in interventional resting-state fMRI studies. Neurosci Res 2021;165:26–37 doi:10.1016/j.neures.2020.05.006 pmid:32464181

   CrossRefPubMed
6. 6.↵
   1. Kelly RE,
   2. Wang Z,
   3. Alexopoulos GS, et al

   . Hybrid ICA-seed-based methods for fMRI functional connectivity assessment: a feasibility study. Int J Biomed Imaging 2010;2010:868976 doi:10.1155/2010/868976 pmid:20689712

   CrossRefPubMed
7. 7.↵
   1. Farahani FV,
   2. Karwowski W,
   3. Lighthall NR

   . Application of graph theory for identifying connectivity patterns in human brain networks: a systematic review. Front Neurosci 2019;13:585 doi:10.3389/fnins.2019.00585 pmid:31249501

   CrossRefPubMed
8. 8.↵
   1. Vedaei F,
   2. Newberg AB,
   3. Alizadeh M, et al

   . Resting-state functional MRI metrics in patients with chronic mild traumatic brain injury and their association with clinical cognitive performance. Front Hum Neurosci 2021;15:768485 doi:10.3389/fnhum.2021.768485 pmid:35027887

   CrossRefPubMed
9. 9.↵
   1. Zou QH,
   2. Zhu CZ,
   3. Yang Y, et al

   . An improved approach to detection of Amplitude of Low-Frequency Fluctuations (ALFF) for resting-state fMRI: fractional ALFF. J Neurosci Methods 2008;172:137–41 doi:10.1016/j.jneumeth.2008.04.012 pmid:18501969

   CrossRefPubMedWeb of Science
10. 10.↵
    1. Wells GA,
    2. Shea B,
    3. O’Connell D, et al

    . The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. The Ottowa Hospital Research Institute, 2021. https://www.ohri.ca/programs/clinical_epidemiology/oxford.asp. Accessed October 29, 2023
11. 11.↵
    1. Bittencourt M,
    2. van der Horn HJ,
    3. Balart-Sanchez SA, et al

    . Effects of mild traumatic brain injury on resting state brain network connectivity in older adults. Brain Imaging Behav 2022;16:1863–72 doi:10.1007/s11682-022-00662-5 pmid:35394617

    CrossRefPubMed
12. 12.
    1. Kim E,
    2. Seo HG,
    3. Seong MY, et al

    . An exploratory study on functional connectivity after mild traumatic brain injury: preserved global but altered local organization. Brain Behav 2022;12:e2735 doi:10.1002/brb3.2735 pmid:35993893

    CrossRefPubMed
13. 13.
    1. Li F,
    2. Liu Y,
    3. Lu L, et al

    . Rich-club reorganization of functional brain networks in acute mild traumatic brain injury with cognitive impairment. Quant Imaging Med Surg 2022;12:3932–46 doi:10.21037/qims-21-915 pmid:35782237

    CrossRefPubMed
14. 14.
    1. Li W,
    2. Ding S,
    3. Zhao G

    . Static and dynamic topological organization of brain functional connectome in acute mild traumatic brain injury. Acta Radiol 2022;64:1175–83 doi:10.1177/02841851221109897 pmid:35765198

    CrossRefPubMed
15. 15.
    1. Lu L,
    2. Zhang J,
    3. Li F, et al

    . Aberrant static and dynamic functional network connectivity in acute mild traumatic brain injury with cognitive impairment. Clin Neuroradiol 2022;32:205–14 doi:10.1007/s00062-021-01082-6 pmid:34463779

    CrossRefPubMed
16. 16.
    1. Amir J,
    2. Nair JK,
    3. Del Carpio-O’Donovan R, et al

    . Atypical resting state functional connectivity in mild traumatic brain injury. Brain Behav 2021;11:e2261 doi:10.1002/brb3.2261 pmid:34152089

    CrossRefPubMed
17. 17.
    1. Bajaj S,
    2. Raikes AC,
    3. Razi A, et al

    . Blue-light therapy strengthens resting-state effective connectivity within default-mode network after mild TBI. J Cent Nerv Syst Dis 2021;13:11795735211015076 doi:10.1177/11795735211015076 pmid:34104033

    CrossRefPubMed
18. 18.
    1. Bittencourt-Villalpando M,
    2. van der Horn HJ,
    3. Maurits NM, et al

    . Disentangling the effects of age and mild traumatic brain injury on brain network connectivity: a resting state fMRI study. Neuroimage Clin 2021;29:102534 doi:10.1016/j.nicl.2020.102534 pmid:33360020

    CrossRefPubMed
19. 19.
    1. Jia X,
    2. Chang X,
    3. Bai L, et al

    . A longitudinal study of white matter functional network in mild traumatic brain injury. J Neurotrauma 2021;38:2686–97 doi:10.1089/neu.2021.0017 pmid:33906419

    CrossRefPubMed
20. 20.
    1. Shi J,
    2. Teng J,
    3. Du X, et al

    . Multi-modal analysis of resting-state fMRI data in mTBI patients and association with neuropsychological outcomes. Front Neurol 2021;12:639760 doi:10.3389/fneur.2021.639760 pmid:34079510

    CrossRefPubMed
21. 21.
    1. Sun Y,
    2. Wang S,
    3. Gan S, et al

    . Serum neuron-specific enolase levels associated with connectivity alterations in anterior default mode network after mild traumatic brain injury. J Neurotrauma 2021;38:1495–505 doi:10.1089/neu.2020.7372 pmid:33687275

    CrossRefPubMed
22. 22.
    1. Wang T,
    2. Hu Y,
    3. Wang D, et al

    . Arcuate fasciculus subsegment impairments distinctly associated with memory and language deficits in acute mild traumatic brain injury patients. J Neurotrauma 2021;38:3279–87 doi:10.1089/neu.2021.0267 pmid:34605664

    CrossRefPubMed
23. 23.
    1. Wang Z,
    2. Zhang M,
    3. Sun C, et al

    . Single mild traumatic brain injury deteriorates progressive interhemispheric functional and structural connectivity. J Neurotrauma 2021;38:464–73 doi:10.1089/neu.2018.6196 pmid:30931824

    CrossRefPubMed
24. 24.
    1. Zhang D,
    2. Zhu P,
    3. Yin B, et al

    . Frontal white matter hyperintensities effect on default mode network connectivity in acute mild traumatic brain injury. Front Aging Neurosci 2021;13:793491 doi:10.3389/fnagi.2021.793491 pmid:35250532

    CrossRefPubMed
25. 25.
    1. D’Souza MM,
    2. Kumar M,
    3. Choudhary A, et al

    . Alterations of connectivity patterns in functional brain networks in patients with mild traumatic brain injury: a longitudinal resting-state functional magnetic resonance imaging study. Neuroradiol J 2020;33:186–97 doi:10.1177/1971400920901706 pmid:31992126

    CrossRefPubMed
26. 26.
    1. Li F,
    2. Lu L,
    3. Chen H, et al

    . Neuroanatomical and functional alterations of insula in mild traumatic brain injury patients at the acute stage. Brain Imaging Behav 2020;14:907–16 doi:10.1007/s11682-019-00053-3 pmid:30734204

    CrossRefPubMed
27. 27.
    1. Li F,
    2. Lu L,
    3. Shang S, et al

    . Disrupted functional network connectivity predicts cognitive impairment after acute mild traumatic brain injury. CNS Neurosci Ther 2020;26:1083–91 doi:10.1111/cns.13430 pmid:32588522

    CrossRefPubMed
28. 28.
    1. Liu Y,
    2. Wu W,
    3. Chen X, et al

    . Aberrant correlation between the default mode and salience networks in mild traumatic brain injury. Front Comput Neurosci 2020;14:68 doi:10.3389/fncom.2020.00068 pmid:32848686

    CrossRefPubMed
29. 29.
    1. Lu L,
    2. Li F,
    3. Chen H, et al

    . Functional connectivity dysfunction of insular subdivisions in cognitive impairment after acute mild traumatic brain injury. Brain Imaging Behav 2020;14:941–48 doi:10.1007/s11682-020-00288-5 pmid:32304021

    CrossRefPubMed
30. 30.
    1. Lu L,
    2. Li F,
    3. Wang P, et al

    . Altered hypothalamic functional connectivity in post-traumatic headache after mild traumatic brain injury. J Headache Pain 2020;21:93 doi:10.1186/s10194-020-01164-9 pmid:32723299

    CrossRefPubMed
31. 31.
    1. Shafi R,
    2. Crawley AP,
    3. Tartaglia MC, et al

    . Sex-specific differences in resting-state functional connectivity of large-scale networks in postconcussion syndrome. Sci Rep 2020;10:21982 doi:10.1038/s41598-020-77137-4 pmid:33319807

    CrossRefPubMed
32. 32.
    1. Chong CD,
    2. Wang L,
    3. Wang K, et al

    . Homotopic region connectivity during concussion recovery: a longitudinal fMRI study. PLoS One 2019;14:e0221892 doi:10.1371/journal.pone.0221892 pmid:31577811

    CrossRefPubMed
33. 33.
    1. Hou W,
    2. Sours Rhodes C,
    3. Jiang L, et al

    . Dynamic functional network analysis in mild traumatic brain injury. Brain Connect 2019;9:475–87 doi:10.1089/brain.2018.0629 pmid:30982332

    CrossRefPubMed
34. 34.
    1. Kuceyeski AF,
    2. Jamison KW,
    3. Owen JP, et al

    . Longitudinal increases in structural connectome segregation and functional connectome integration are associated with better recovery after mild TBI. Hum Brain Mapp 2019;40:4441–56 doi:10.1002/hbm.24713 pmid:31294921

    CrossRefPubMed
35. 35.
    1. Li F,
    2. Lu L,
    3. Chen H, et al

    . Disrupted brain functional hub and causal connectivity in acute mild traumatic brain injury. Aging (Albany NY) 2019;11:10684–96 doi:10.18632/aging.102484 pmid:31754082

    CrossRefPubMed
36. 36.
    1. Lu L,
    2. Li F,
    3. Ma Y, et al

    . Functional connectivity disruption of the substantia nigra associated with cognitive impairment in acute mild traumatic brain injury. Eur J Radiol 2019;114:69–75 doi:10.1016/j.ejrad.2019.03.002 pmid:31005180

    CrossRefPubMed
37. 37.
    1. Niu X,
    2. Bai L,
    3. Sun Y, et al

    . Disruption of periaqueductal grey-default mode network functional connectivity predicts persistent post-traumatic headache in mild traumatic brain injury. J Neurol Neurosurg Psychiatry 2019;90:326–32 doi:10.1136/jnnp-2018-318886 pmid:30554137

    Abstract/FREE Full Text
38. 38.
    1. Dailey NS,
    2. Smith R,
    3. Vanuk JR, et al

    . Resting-state functional connectivity as a biomarker of aggression in mild traumatic brain injury. Neuroreport 2018;29:1413–17 doi:10.1097/WNR.0000000000001127 pmid:30204638

    CrossRefPubMed
39. 39.
    1. Wang S,
    2. Hu L,
    3. Cao J, et al

    . Sex differences in abnormal intrinsic functional connectivity after acute mild traumatic brain injury. Front Neural Circuits 2018;12:107 doi:10.3389/fncir.2018.00107 pmid:30555304

    CrossRefPubMed
40. 40.
    1. Xu H,
    2. Wang X,
    3. Chen Z, et al

    . Longitudinal changes of caudate-based resting state functional connectivity in mild traumatic brain injury. Front Neurol 2018;9:467 doi:10.3389/fneur.2018.00467 pmid:29973909

    CrossRefPubMed
41. 41.
    1. Dall'Acqua P,
    2. Johannes S,
    3. Mica L, et al

    . Functional and structural network recovery after mild traumatic brain injury: a 1-year longitudinal study. Front Hum Neurosci 2017;11:280 doi:10.3389/fnhum.2017.00280 pmid:28611614

    CrossRefPubMed
42. 42.
    1. Palacios EM,
    2. Yuh EL,
    3. Chang YS, et al

    . Resting-state functional connectivity alterations associated with six-month outcomes in mild traumatic brain injury. J Neurotrauma 2017;34:1546–57 doi:10.1089/neu.2016.4752 pmid:28085565

    CrossRefPubMed
43. 43.
    1. Rajesh A,
    2. Cooke GE,
    3. Monti JM, et al

    . Differences in brain architecture in remote mild traumatic brain injury. J Neurotrauma 2017;34:3280–87 doi:10.1089/neu.2017.5047 pmid:28726543

    CrossRefPubMed
44. 44.
    1. van der Horn HJ,
    2. Liemburg EJ,
    3. Scheenen ME, et al

    . Graph analysis of functional brain networks in patients with mild traumatic brain injury. PLoS One 2017;12:e0171031 doi:10.1371/journal.pone.0171031 pmid:28129397

    CrossRefPubMed
45. 45.
    1. van der Horn HJ,
    2. Scheenen ME,
    3. de Koning ME, et al

    . The default mode network as a biomarker of persistent complaints after mild traumatic brain injury: a longitudinal functional magnetic resonance imaging study. J Neurotrauma 2017;34:3262–69 doi:10.1089/neu.2017.5185 pmid:28882089

    CrossRefPubMed
46. 46.
    1. Vergara VM,
    2. Mayer AR,
    3. Kiehl KA, et al

    . Dynamic functional network connectivity discriminates mild traumatic brain injury through machine learning. Neuroimage Clin 2018;19:30–37 doi:10.1016/j.nicl.2018.03.017 pmid:30034999

    CrossRefPubMed
47. 47.
    1. Vergara VM,
    2. Mayer AR,
    3. Damaraju E, et al

    . Detection of mild traumatic brain injury by machine learning classification using resting state functional network connectivity and fractional anisotropy. J Neurotrauma 2017;34:1045–53 doi:10.1089/neu.2016.4526 pmid:27676221

    CrossRefPubMed
48. 48.
    1. Yan H,
    2. Sun C,
    3. Wang X, et al

    . Deteriorating neural connectivity of the hippocampal episodic memory network in mTBI patients: acohort study. In: Proceedings of the International Joint Conference on Neural Networks, May 14–19; 2017:2979–86. Anchorage, Alaska
49. 49.
    1. Yan Y,
    2. Song J,
    3. Xu G, et al

    . Correlation between standardized assessment of concussion scores and small-world brain network in mild traumatic brain injury. J Clin Neurosci 2017;44:114–21 doi:10.1016/j.jocn.2017.05.010 pmid:28602630

    CrossRefPubMed
50. 50.
    1. Zhou Y

    . Abnormal structural and functional hypothalamic connectivity in mild traumatic brain injury. J Magn Reson Imaging 2017;45:1105–12 doi:10.1002/jmri.25413 pmid:27467114

    CrossRefPubMed
51. 51.
    1. Astafiev SV,
    2. Zinn KL,
    3. Shulman GL, et al

    . Exploring the physiological correlates of chronic mild traumatic brain injury symptoms. Neuroimage Clin 2016;11:10–19 doi:10.1016/j.nicl.2016.01.004 pmid:26909324

    CrossRefPubMed
52. 52.
    1. Banks SD,
    2. Coronado RA,
    3. Clemons LR, et al

    . Thalamic functional connectivity in mild traumatic brain injury: longitudinal associations with patient-reported outcomes and neuropsychological tests. Arch Phys Med Rehabil 2016;97:1254–61 doi:10.1016/j.apmr.2016.03.013 pmid:27085849

    CrossRefPubMed
53. 53.
    1. Iraji A,
    2. Chen H,
    3. Wiseman N, et al

    . Compensation through functional hyperconnectivity: A longitudinal connectome assessment of mild traumatic brain injury. Neural Plast 2016;2016:4072402 doi:10.1155/2016/4072402 pmid:26819765

    CrossRefPubMed
54. 54.
    1. Nordin LE,
    2. Moller MC,
    3. Julin P, et al

    . Post mTBI fatigue is associated with abnormal brain functional connectivity. Sci Rep 2016;6:21183 doi:10.1038/srep21183 pmid:26878885

    CrossRefPubMed
55. 55.
    1. van der Horn HJ,
    2. Liemburg EJ,
    3. Scheenen ME, et al

    . Brain network dysregulation, emotion, and complaints after mild traumatic brain injury. Hum Brain Mapp 2016;37:1645–54 doi:10.1002/hbm.23126 pmid:26846195

    CrossRefPubMed
56. 56.
    1. Xiong KL,
    2. Zhang JN,
    3. Zhang YL, et al

    . Brain functional connectivity and cognition in mild traumatic brain injury. Neuroradiology 2016;58:733–39 doi:10.1007/s00234-016-1675-0 pmid:27000797

    CrossRefPubMed
57. 57.
    1. Yan H,
    2. Feng Y,
    3. Wang Q

    . Altered effective connectivity of hippocampus-dependent episodic memory network in mTBI survivors. Neural Plast 2016;2016:6353845 doi:10.1155/2016/6353845 pmid:28074162

    CrossRefPubMed
58. 58.
    1. Bharath RD,
    2. Munivenkatappa A,
    3. Gohel S, et al

    . Recovery of resting brain connectivity ensuing mild traumatic brain injury. Front Hum Neurosci 2015;9:513 doi:10.3389/fnhum.2015.00513 pmid:26441610

    CrossRefPubMed
59. 59.
    1. Iraji A,
    2. Benson RR,
    3. Welch RD, et al

    . Resting state functional connectivity in mild traumatic brain injury at the acute stage: independent component and seed-based analyses. J Neurotrauma 2015;32:1031–45 doi:10.1089/neu.2014.3610 pmid:25285363

    CrossRefPubMed
60. 60.
    1. Mayer AR,
    2. Ling JM,
    3. Allen EA, et al

    . Static and dynamic intrinsic connectivity following mild traumatic brain injury. J Neurotrauma 2015;32:1046–55 doi:10.1089/neu.2014.3542 pmid:25318005

    CrossRefPubMed
61. 61.
    1. Sours C,
    2. Chen H,
    3. Roys S, et al

    . Investigation of multiple frequency ranges using discrete wavelet decomposition of resting-state functional connectivity in mild traumatic brain injury patients. Brain Connect 2015;5:442–50 doi:10.1089/brain.2014.0333 pmid:25808612

    CrossRefPubMed
62. 62.
    1. Sours C,
    2. George E,
    3. Zhuo JC, et al

    . Hyper-connectivity of the thalamus during early stages following mild traumatic brain injury. Brain Imaging Behav 2015;9:550–63 doi:10.1007/s11682-015-9424-2 pmid:26153468

    CrossRefPubMed
63. 63.
    1. Sours C,
    2. Rosenberg J,
    3. Kane R, et al

    . Associations between interhemispheric functional connectivity and the Automated Neuropsychological Assessment Metrics (ANAM) in civilian mild TBI. Brain Imaging Behav 2015;9:190–203 doi:10.1007/s11682-014-9295-y pmid:24557591

    CrossRefPubMed
64. 64.
    1. Sours C,
    2. Zhuo J,
    3. Roys S, et al

    . Disruptions in resting state functional connectivity and cerebral blood flow in mild traumatic brain injury patients. PLoS One 2015;10:e0134019 doi:10.1371/journal.pone.0134019 pmid:26241476

    CrossRefPubMed
65. 65.
    1. Vergara VM,
    2. Damaraju E,
    3. Mayer AB, et al

    . The impact of data preprocessing in traumatic brain injury detection using functional magnetic resonance imaging. In: Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, August 25–29, 2015:5432–35 Milan, Italy
66. 66.
    1. Zhan J,
    2. Gao L,
    3. Zhou F, et al

    . Decreased regional homogeneity in patients with acute mild traumatic brain injury: a resting-state fMRI study. J Nerv Ment Dis 2015;203:786–91 doi:10.1097/NMD.0000000000000368 pmid:26348589

    CrossRefPubMed
67. 67.
    1. Zhou Y,
    2. Lui YW,
    3. Zuo XN, et al

    . Characterization of thalamo-cortical association using amplitude and connectivity of functional MRI in mild traumatic brain injury. J Magn Reson Imaging 2014;39:1558–68 doi:10.1002/jmri.24310 pmid:24014176

    CrossRefPubMed
68. 68.
    1. Messe A,
    2. Caplain S,
    3. Pelegrini-Issac M, et al

    . Specific and evolving resting-state network alterations in post-concussion syndrome following mild traumatic brain injury. PLoS One 2013;8:e65470 doi:10.1371/journal.pone.0065470 pmid:23755237

    CrossRefPubMed
69. 69.
    1. Sours C,
    2. Zhuo J,
    3. Janowich J, et al

    . Default mode network interference in mild traumatic brain injury: a pilot resting state study. Brain Res 2013;1537:201–15 doi:10.1016/j.brainres.2013.08.034 pmid:23994210

    CrossRefPubMed
70. 70.↵
    1. Shumskaya E,
    2. Andriessen T,
    3. Norris DG, et al

    . Abnormal whole-brain functional networks in homogeneous acute mild traumatic brain injury. Neurology 2012;79:175–82 doi:10.1212/WNL.0b013e31825f04fb pmid:22744656

    Abstract/FREE Full Text
71. 71.
    1. Zhou Y,
    2. Milham MP,
    3. Lui YW, et al

    . Default-mode network disruption in mild traumatic brain injury. Radiology 2012;265:882–92 doi:10.1148/radiol.12120748 pmid:23175546

    CrossRefPubMed
72. 72.↵
    1. Tang L,
    2. Ge Y,
    3. Sodickson DK, et al

    . Thalamic resting-state functional networks: disruption in patients with mild traumatic brain injury. Radiology 2011;260:831–40 doi:10.1148/radiol.11110014 pmid:21775670

    CrossRefPubMed
73. 73.↵
    1. Wang S,
    2. Gan S,
    3. Yang X, et al

    . Decoupling of structural and functional connectivity in hubs and cognitive impairment after mild traumatic brain injury. Brain Connect 2021;11:745–58 doi:10.1089/brain.2020.0852 pmid:33605188

    CrossRefPubMed
74. 74.↵
    1. Sullivan DR

    . A cerebrovascular hypothesis of neurodegeneration in mTBI. J Head Trauma Rehabil 2019;34:E18–27 doi:10.1097/HTR.0000000000000449 pmid:30499930

    CrossRefPubMed
75. 75.↵
    1. Baker TL,
    2. Agoston DV,
    3. Brady RD, et al

    . Targeting the cerebrovascular system: next-generation biomarkers and treatment for mild traumatic brain injury. Neuroscientist 2021;28:594–612 doi:10.1177/10738584211012264 pmid:33966527

    CrossRefPubMed
76. 76.↵
    1. Chong JS,
    2. Liu S,
    3. Loke YM, et al

    . Influence of cerebrovascular disease on brain networks in prodromal and clinical Alzheimer’s disease. Brain 2017;140:3012–22 doi:10.1093/brain/awx224 pmid:29053778

    CrossRefPubMed