Skip to main content
Advertisement

Main menu

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Other Publications
    • ajnr

User menu

  • Alerts
  • Log in

Search

  • Advanced search
American Journal of Neuroradiology
American Journal of Neuroradiology

American Journal of Neuroradiology

ASHNR American Society of Functional Neuroradiology ASHNR American Society of Pediatric Neuroradiology ASSR
  • Alerts
  • Log in

Advanced Search

  • Home
  • Content
    • Current Issue
    • Accepted Manuscripts
    • Article Preview
    • Past Issue Archive
    • AJNR Case Collection
    • Case of the Week Archive
    • Classic Case Archive
    • Case of the Month Archive
  • Special Collections
    • Spinal CSF Leak Articles (Jan 2020-June 2024)
    • 2024 AJNR Journal Awards
    • Most Impactful AJNR Articles
  • Multimedia
    • AJNR Podcast
    • AJNR Scantastics
    • Video Articles
  • For Authors
    • Submit a Manuscript
    • Author Policies
    • Fast publishing of Accepted Manuscripts
    • Graphical Abstract Preparation
    • Manuscript Submission Guidelines
    • Imaging Protocol Submission
    • Submit a Case for the Case Collection
  • About Us
    • About AJNR
    • Editorial Board
  • More
    • Become a Reviewer/Academy of Reviewers
    • Subscribers
    • Permissions
    • Alerts
    • Feedback
    • Advertisers
    • ASNR Home
  • Follow AJNR on Twitter
  • Visit AJNR on Facebook
  • Follow AJNR on Instagram
  • Join AJNR on LinkedIn
  • RSS Feeds

Welcome to the new AJNR, Updated Hall of Fame, and more. Read the full announcements.


AJNR is seeking candidates for the position of Associate Section Editor, AJNR Case Collection. Read the full announcement.

 

Research ArticleHead and Neck Imaging

Clinical and Imaging Features of Head and Neck Metastasis of High-Grade Glioma: A Single-Center Case Series

Rami W. Eldaya, Diana Kaya, Michelle Williams, Susana Calle and Dawid Schellingerhout
American Journal of Neuroradiology January 2025, 46 (1) 160-165; DOI: https://doi.org/10.3174/ajnr.A8521
Rami W. Eldaya
aFrom the Department of Neuroradiology (R.W.E., D.K., S.C.), The University of Texas MD Anderson Cancer Center, Houston, Texas
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Rami W. Eldaya
Diana Kaya
aFrom the Department of Neuroradiology (R.W.E., D.K., S.C.), The University of Texas MD Anderson Cancer Center, Houston, Texas
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Diana Kaya
Michelle Williams
bDepartment of Anatomical Pathology (M.W.), The University of Texas MD Anderson Cancer Center, Houston, Texas
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Michelle Williams
Susana Calle
aFrom the Department of Neuroradiology (R.W.E., D.K., S.C.), The University of Texas MD Anderson Cancer Center, Houston, Texas
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Susana Calle
Dawid Schellingerhout
cDepartments of Neuroradiology and Imaging Physics (D.S.), The University of Texas MD Anderson Cancer Center, Houston, Texas
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • ORCID record for Dawid Schellingerhout
  • Article
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF
Loading

References

  1. 1.↵
    1. Zhang W,
    2. Cai YY,
    3. Wang XL, et al
    . Bone metastases of glioblastoma: a case report and review of the literature. Front Oncol 2021;11:705455 doi:10.3389/fonc.2021.705455 pmid:34646764
    CrossRefPubMed
  2. 2.↵
    1. Sanson M,
    2. Marie Y,
    3. Paris S, et al
    . Isocitrate dehydrogenase 1 codon 132 mutation is an important prognostic biomarker in gliomas. J Clin Oncol 2009;27:4150–54 doi:10.1200/JCO.2009.21.9832 pmid:19636000
    Abstract/FREE Full Text
  3. 3.↵
    1. Weller M,
    2. Felsberg J,
    3. Hartmann C, et al
    . Molecular predictors of progression-free and overall survival in patients with newly diagnosed glioblastoma: a prospective translational study of the German Glioma Network. J Clin Oncol 2009;27:5743–50 doi:10.1200/JCO.2009.23.0805 pmid:19805672
    Abstract/FREE Full Text
  4. 4.↵
    1. Hertler C,
    2. Felsberg J,
    3. Gramatzki D, et al
    . Long-term survival with IDH wildtype glioblastoma: first results from the ETERNITY Brain Tumor Funders’ Collaborative Consortium (EORTC 1419). Eur J Cancer 2023;189:112913 doi:10.1016/j.ejca.2023.05.002 pmid:37277265
    CrossRefPubMed
  5. 5.↵
    WHO Classification of Tumours Editorial Board. Central Nervous System Tumors. 5th ed. International Agency for Research on Cancer; 2022 (beta online version).
  6. 6.↵
    WHO Classification of Tumours Editorial Board. Genetic Tumour Syndromes. 5th ed. International Agency for Research on Cancer; 2021.
  7. 7.↵
    1. Louis DN,
    2. Aldape K,
    3. Brat DJ, et al
    . cIMPACT-NOW (the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy): a new initiative in advancing nervous system tumor classification. Brain Pathol 2017;27:851–52 doi:10.1111/bpa.12457 pmid:27997995
    CrossRefPubMed
  8. 8.↵
    1. Louis DN,
    2. Aldape K,
    3. Brat DJ, et al
    . Announcing cIMPACT-NOW: the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy. Acta Neuropathol 2017;133:1–3 doi:10.1007/s00401-016-1646-x pmid:27909809
    CrossRefPubMed
  9. 9.↵
    1. Louis DN,
    2. Giannini C,
    3. Capper D, et al
    . cIMPACT-NOW update 2: diagnostic clarifications for diffuse midline glioma, H3 K27M-mutant and diffuse astrocytoma/anaplastic astrocytoma, IDH-mutant. Acta Neuropathol 2018;135:639–42 doi:10.1007/s00401-018-1826-y pmid:29497819
    CrossRefPubMed
  10. 10.↵
    1. Ellison DW,
    2. Hawkins C,
    3. Jones DTW, et al
    . cIMPACT-NOW update 4: diffuse gliomas characterized by MYB, MYBL1, or FGFR1 alterations or BRAFV600E mutation. Acta Neuropathol 2019;137:683–87 doi:10.1007/s00401-019-01987-0 pmid:30848347
    CrossRefPubMed
  11. 11.↵
    1. Brat DJ,
    2. Aldape K,
    3. Colman H, et al
    . cIMPACT-NOW update 3: recommended diagnostic criteria for “Diffuse astrocytic glioma, IDH-wildtype, with molecular features of glioblastoma, WHO grade IV. Acta Neuropathol 2018;136:805–10 doi:10.1007/s00401-018-1913-0 pmid:30259105
    CrossRefPubMed
  12. 12.↵
    1. Louis DN,
    2. Ellison DW,
    3. Brat DJ, et al
    . cIMPACT-NOW: a practical summary of diagnostic points from round 1 updates. Brain Pathol 2019;29:469–72 doi:10.1111/bpa.12732 pmid:31038238
    CrossRefPubMed
  13. 13.↵
    1. Louis DN,
    2. Wesseling P,
    3. Aldape K, et al
    . cIMPACT-NOW update 6: new entity and diagnostic principle recommendations of the cIMPACT-Utrecht meeting on future CNS tumor classification and grading. Brain Pathol 2020;30:844–56 doi:10.1111/bpa.12832 pmid:32307792
    CrossRefPubMed
  14. 14.↵
    1. Vertosick F,
    2. Selker R
    . Brain stem and spinal metastases of supratentorial glioblastoma multiforme: a clinical series. Neurosurgery 1990;27:516–21 doi:10.1227/00006123-199010000-00002 pmid:2172859
    CrossRefPubMedWeb of Science
  15. 15.↵
    1. Hamilton J,
    2. Rapp M,
    3. Schneiderhan T, et al
    . Glioblastoma multiforme metastasis outside the CNS three case reports and possible mechanisms of escape. J Clin Oncol 2014;32:e80–84 doi:10.1200/JCO.2013.48.7546 pmid:24567434
    FREE Full Text
  16. 16.↵
    1. Beauchesne P
    . Extra-neural metastases of malignant gliomas: myth or reality? Cancers (Basel) 2011;3:461–77 doi:10.3390/cancers3010461 pmid:24212625
    CrossRefPubMed
  17. 17.↵
    1. Rajagopalan V,
    2. El Kamar F,
    3. Thayaparan R, et al
    . Bone marrow metastases from glioblastoma multiforme–a case report and review of the literature. J Neurooncol 2005;72:157–61 doi:10.1007/s11060-004-3346-y
    CrossRefPubMed
  18. 18.↵
    1. Noch EK,
    2. Sait SF,
    3. Farooq S, et al
    . A case series of extraneural metastatic glioblastoma at Memorial Sloan Kettering Cancer Center. Neurooncol Pract 2021;8:325–36 doi:10.1093/nop/npaa083 pmid:34055380
    CrossRefPubMed
  19. 19.↵
    1. Lun M,
    2. Lok E,
    3. Gautam S, et al
    . The natural history of extracranial metastasis from glioblastoma multiforme. J Neurooncol 2011;105:261–73 doi:10.1007/s11060-011-0575-8 pmid:21512826
    CrossRefPubMed
  20. 20.↵
    1. Wakabayashi T,
    2. Yoshida J,
    3. Kageyama N, et al
    . Extraneural metastasis of malignant glioma through a ventriculo-peritoneal shunt: growth in peritoneal cavity as ascitic form. Article in Japanese. No Shinkei Geka Neurol Surg 1985;13:547–52
  21. 21.↵
    1. Seo YJ,
    2. Cho WH,
    3. Kang DW, et al
    . Extraneural metastasis of glioblastoma multiforme presenting as an unusual neck mass. J Korean Neurosurg Soc 2012;51:147–50 doi:10.3340/jkns.2012.51.3.147 pmid:22639711
    CrossRefPubMed
  22. 22.↵
    1. González Cámpora R,
    2. Otal Salaverri C,
    3. Vázquez Ramirez F, et al
    . Metastatic glioblastoma multiforme in cervical lymph nodes. Report of a case with diagnosis by fine needle aspiration. Acta Cytol 1993;37:938–42 pmid:8249517
    PubMed
  23. 23.↵
    1. Lah TT,
    2. Novak M,
    3. Breznik B
    . Brain malignancies: glioblastoma and brain metastases. Semin Cancer Biol 2020;60:262–73 doi:10.1016/j.semcancer.2019.10.010 pmid:31654711
    CrossRefPubMed
  24. 24.↵
    1. Ostrom QT,
    2. Gittleman H,
    3. Liao P, et al
    . CBTRUS Statistical Report: primary brain and other central nervous system tumors diagnosed in the United States in 2010-2014. Neuro Oncol 2017;19:v1–v88 doi:10.1093/neuonc/nox158 pmid:29117289
    CrossRefPubMed
  25. 25.↵
    1. Ostrom QT,
    2. Cote DJ,
    3. Ascha M, et al
    . Adult glioma incidence and survival by race or ethnicity in the United States from 2000 to 2014. JAMA Oncol 2018;4:1254–62 doi:10.1001/jamaoncol.2018.1789 pmid:29931168
    CrossRefPubMed
  26. 26.↵
    1. Cunha MLVD,
    2. Maldaun MVC
    . Metastasis from glioblastoma multiforme: a meta-analysis. Rev Assoc Med Bras (1992) 2019;65:424–33 doi:10.1590/1806-9282.65.3.424 pmid:30994843
    CrossRefPubMed
  27. 27.↵
    1. Anzil AP
    . Glioblastoma multiforme with extracranial metastases in the absence of previous craniotomy. Case report. J Neurosurg 1970;33:88–94 doi:10.3171/jns.1970.33.1.0088 pmid:4316740
    CrossRefPubMed
  28. 28.↵
    1. Wassati H,
    2. Loo SW,
    3. Low HL
    . Lymphatic metastasis due to glioblastoma. Neurosciences (Riyadh) 2016;21:168–69 doi:10.17712/nsj.2016.2.20150497 pmid:27094530
    CrossRefPubMed
  29. 29.↵
    1. Mujtaba SS,
    2. Haroon S,
    3. Faridi N
    . Cervical metastatic glioblastoma multiforme. J Coll Physicians Surg Pak 2013;23:160–61 pmid:23374526
    PubMed
  30. 30.↵
    1. Klop WM,
    2. Veenstra HJ,
    3. Vermeeren L, et al
    . Assessment of lymphatic drainage patterns and implications for the extent of neck dissection in head and neck melanoma patients. J Surg Oncol 2011;103:756–60 doi:10.1002/jso.21865 pmid:21283993
    CrossRefPubMed
PreviousNext
Back to top

In this issue

American Journal of Neuroradiology: 46 (1)
American Journal of Neuroradiology
Vol. 46, Issue 1
1 Jan 2025
  • Table of Contents
  • Index by author
  • Complete Issue (PDF)
Advertisement
Print
Download PDF
Email Article

Thank you for your interest in spreading the word on American Journal of Neuroradiology.

NOTE: We only request your email address so that the person you are recommending the page to knows that you wanted them to see it, and that it is not junk mail. We do not capture any email address.

Enter multiple addresses on separate lines or separate them with commas.
Clinical and Imaging Features of Head and Neck Metastasis of High-Grade Glioma: A Single-Center Case Series
(Your Name) has sent you a message from American Journal of Neuroradiology
(Your Name) thought you would like to see the American Journal of Neuroradiology web site.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Cite this article
Rami W. Eldaya, Diana Kaya, Michelle Williams, Susana Calle, Dawid Schellingerhout
Clinical and Imaging Features of Head and Neck Metastasis of High-Grade Glioma: A Single-Center Case Series
American Journal of Neuroradiology Jan 2025, 46 (1) 160-165; DOI: 10.3174/ajnr.A8521

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
0 Responses
Respond to this article
Share
Bookmark this article
Head/Neck Metastasis in High-Grade Gliomas
Rami W. Eldaya, Diana Kaya, Michelle Williams, Susana Calle, Dawid Schellingerhout
American Journal of Neuroradiology Jan 2025, 46 (1) 160-165; DOI: 10.3174/ajnr.A8521
del.icio.us logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One
Purchase

Jump to section

  • Article
    • Abstract
    • ABBREVIATIONS:
    • CASE SERIES
    • RESULTS
    • DISCUSSION
    • CONCLUSIONS
    • Footnotes
    • References
  • Figures & Data
  • Info & Metrics
  • Responses
  • References
  • PDF

Related Articles

  • No related articles found.
  • PubMed
  • Google Scholar

Cited By...

  • No citing articles found.
  • Crossref
  • Google Scholar

This article has not yet been cited by articles in journals that are participating in Crossref Cited-by Linking.

More in this TOC Section

  • CT facial recess and hard cochlear implantation
  • Imaging Hyrtl Fissure: Congenital CSF Otorrhea
  • Vestibular Schwannoma: PostGad Signal & Hearing Loss
Show more Head and Neck Imaging

Similar Articles

Advertisement

Indexed Content

  • Current Issue
  • Accepted Manuscripts
  • Article Preview
  • Past Issues
  • Editorials
  • Editors Choice
  • Fellow Journal Club
  • Letters to the Editor

Cases

  • Case Collection
  • Archive - Case of the Week
  • Archive - Case of the Month
  • Archive - Classic Case

Special Collections

  • Special Collections

Resources

  • News and Updates
  • Turn around Times
  • Submit a Manuscript
  • Author Policies
  • Manuscript Submission Guidelines
  • Evidence-Based Medicine Level Guide
  • Publishing Checklists
  • Graphical Abstract Preparation
  • Imaging Protocol Submission
  • Submit a Case
  • Become a Reviewer/Academy of Reviewers
  • Get Peer Review Credit from Publons

Multimedia

  • AJNR Podcast
  • AJNR SCANtastic
  • Video Articles

About Us

  • About AJNR
  • Editorial Board
  • Not an AJNR Subscriber? Join Now
  • Alerts
  • Feedback
  • Advertise with us
  • Librarian Resources
  • Permissions
  • Terms and Conditions

American Society of Neuroradiology

  • Not an ASNR Member? Join Now

© 2025 by the American Society of Neuroradiology All rights, including for text and data mining, AI training, and similar technologies, are reserved.
Print ISSN: 0195-6108 Online ISSN: 1936-959X

Powered by HighWire