More articles from Pediatrics
- Brain Maturation Patterns on Normalized FLAIR MR Imaging in Children and Adolescents
Studies to date have shown signal maturation patterns in the pediatric population using various sequences. However, there is a paucity of information about brain maturation patterns of FLAIR signal intensities across the pediatric range. Additionally, intensities vary widely across FLAIR MR imaging scanners. A FLAIR intensity standardization algorithm would be helpful to normalize intensity across large data sets, allowing comparison of FLAIR intensity in different regions and individuals.
- Epileptogenic Tubers Are Associated with Increased Kurtosis of Susceptibility Values: A Combined Quantitative Susceptibility Mapping and Stereoelectroencephalography Pilot Study
Ten patients with tubers related to tuberous sclerosis complex underwent quantitative susceptibility mapping. The QSM and R2* distributions from tubers studied with stereoelectroencephalography demonstrated that increased kurtosis of quantitative susceptibility mapping values was highly specific and associated with epileptogenicity.
- T2-FLAIR Mismatch Sign in Pediatric Low-Grade Glioma
The T2-FLAIR mismatch sign was not observed in pediatric low-grade gliomas with the common molecular alterations BRAF p.V600E–mutated and KIAA1549-BRAF fused, while it was encountered in low-grade gliomas with rare pediatric molecular alterations.